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Surgery is a medical specialty that uses manual and/or instrumental techniques to physically reach into a subject's body in order to investigate or treat pathological conditions such as a disease or injury, to alter bodily functions, to improve appearance, or to remove/replace unwanted tissues or foreign bodies. The subject receiving the surgery is typically a person, but can also be a non-human animal.
Anesthesia or anaesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia, paralysis, amnesia, and unconsciousness. An individual under the effects of anesthetic drugs is referred to as being anesthetized.
Chloroform, or trichloromethane, is an organic compound with the formula CHCl3 and a common solvent. It is a very volatile, colorless, strong-smelling, dense liquid produced on a large scale as a precursor to refrigerants and PTFE. Chloroform is a trihalomethane that serves as a powerful anesthetic, euphoriant, anxiolytic, and sedative when inhaled or ingested. Chloroform was used as an anesthetic between the 19th century and the first half of the 20th century. It is miscible with many solvents but it is only very slightly soluble in water.
Dissociatives, colloquially dissos, are a subclass of hallucinogens which distort perception of sight and sound and produce feelings of detachment – dissociation – from the environment and/or self. Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include dissociation, a general decrease in sensory experience, hallucinations, dream-like states or anesthesia. Despite most dissociatives' main mechanism of action being tied to NMDA receptor antagonism, some of these substances, which are nonselective in action and affect the dopamine and/or opioid systems, may be capable of inducing more direct and repeatable euphoria or symptoms which are more akin to the effects of typical "hard drugs" or common drugs of abuse. This is likely why dissociatives are considered to be addictive with a fair to moderate potential for abuse, unlike psychedelics. Despite some dissociatives, such as phencyclidine (PCP) possessing stimulating properties, most dissociatives seem to have a general depressant effect and can produce sedation, respiratory depression, nausea, disorientation, analgesia, anesthesia, ataxia, cognitive and memory impairment as well as amnesia.
Anesthesiology, anaesthesiology, or anaesthesia is the medical specialty concerned with the total perioperative care of patients before, during and after surgery. It encompasses anesthesia, intensive care medicine, critical emergency medicine, and pain medicine. A physician specialized in anesthesiology is called an anesthesiologist, anaesthesiologist, or anaesthetist, depending on the country. In some countries the terms are synonymous, while in other countries they refer to different positions and anesthetist is only used for non-physicians, such as nurse anesthetists.
William Thomas Green Morton was an American dentist and physician who first publicly demonstrated the use of inhaled ether as a surgical anesthetic in 1846. The promotion of his questionable claim to have been the discoverer of anesthesia became an obsession for the rest of his life.
Horace Wells was an American dentist who pioneered the use of anesthesia in dentistry, specifically the use of nitrous oxide.
John Snow was an English physician and a leader in the development of anaesthesia and medical hygiene. He is considered one of the founders of modern epidemiology and early germ theory, in part because of his work in tracing the source of a cholera outbreak in London's Soho, which he identified as a particular public water pump. Snow's findings inspired fundamental changes in the water and waste systems of London, which led to similar changes in other cities, and a significant improvement in general public health around the world.
An inhalational anesthetic is a chemical compound possessing general anesthetic properties that is delivered via inhalation. They are administered through a face mask, laryngeal mask airway or tracheal tube connected to an anesthetic vaporiser and an anesthetic delivery system. Agents of significant contemporary clinical interest include volatile anesthetic agents such as isoflurane, sevoflurane and desflurane, as well as certain anesthetic gases such as nitrous oxide and xenon.
Sir James Young Simpson, 1st Baronet,, was a Scottish obstetrician and a significant figure in the history of medicine. He was the first physician to demonstrate the anaesthetic properties of chloroform on humans and helped to popularise its use in medicine.
James Marion Sims was an American physician in the field of surgery. His most famous work was the development of a surgical technique for the repair of vesicovaginal fistula, a severe complication of obstructed childbirth. He is also remembered for inventing the Sims speculum, Sims sigmoid catheter, and the Sims position. Against significant opposition, he established, in New York, the first hospital specifically for women. He was forced out of the hospital he founded because he insisted on treating cancer patients; he played a small role in the creation of the nation's first cancer hospital, which opened after his death.
Curare is a common name for various alkaloid arrow poisons originating from plant extracts. Used as a paralyzing agent by indigenous peoples in Central and South America for hunting and for therapeutic purposes, curare only becomes active when it contaminates a wound or is introduced directly to the bloodstream; it is not active when ingested orally. These poisons cause weakness of the skeletal muscles and, when administered in a sufficient dose, eventual death by asphyxiation due to paralysis of the diaphragm. Curare is prepared by boiling the bark of one of the dozens of plant sources, leaving a dark, heavy paste that can be applied to arrow or dart heads. In medicine, curare has been used as a treatment for tetanus and strychnine poisoning and as a paralyzing agent for surgical procedures.
A halogenated ether is a subcategory of a larger group of chemicals known as ethers. An ether is an organic chemical that contains an ether group—an oxygen atom connected to two (substituted) alkyl groups. A good example of an ether is the solvent diethyl ether. What differentiates a halogenated ether from other types of ethers is the substitution (halogenation) of one or more hydrogen atoms with a halogen atom. Halogen atoms include fluorine, chlorine, bromine, and iodine.
John Collins Warren was an American surgeon. In 1846 he gave permission to William T.G. Morton to provide ether anesthesia while Warren performed a minor surgical procedure. News of this first public demonstration of surgical anesthesia quickly circulated around the world. He was a founder of the New England Journal of Medicine and was the third president of the American Medical Association. He was the first Dean of Harvard Medical School and a founding member of the Massachusetts General Hospital.
Harold Randall Griffith was a Canadian anesthesiologist and a leader in the fields of anesthesiology.
Joseph Thomas Clover was an English doctor and innovator of anaesthesia. He invented a variety of pieces of apparatus to deliver anaesthetics, including ether and chloroform, safely and controllably. By 1871 he had administered anaesthetics 13,000 times without a fatality.
ACE mixture is an historical anaesthetic agent for general anaesthesia. It was first suggested by George Harley and first used in England around 1860. In 1864 it was recommended for use by the Royal Medical and Surgical Society's Chloroform Committee. It was rarely used after the 19th century, except in Germany, where it was used for slightly longer.
Throughout recorded history, attempts at producing a state of general anesthesia can be traced back to the writings of ancient Sumerians, Babylonians, Assyrians, Egyptians, Indians, and Chinese. Despite significant advances in anatomy and surgical technique during the Renaissance, surgery remained a last-resort treatment largely due to the pain associated with it. However, scientific discoveries in the late 18th and early 19th centuries paved the way for the development of modern anesthetic techniques.
Obstetric anesthesia or obstetric anesthesiology, also known as ob-gyn anesthesia or ob-gyn anesthesiology, is a sub-specialty of anesthesiology that provides peripartum pain relief (analgesia) for labor and anesthesia for cesarean deliveries ('C-sections').
Isabella Coler Herb was an American medical pioneer in the fields of pathology and anesthesiology. Her career spanned more than half a century, ending with her retirement in 1941. She was the first woman physician to specialize in anesthesiology, and the first Mayo Clinic specialist in her areas of expertise. In 1933, Herb designed the Herb–Mueller apparatus for administering ether to patients. She was the head of the Department of Anesthesia at Presbyterian Hospital, and the first woman president of the American Association of Anesthetists.
References
- 1 2 Thomas, K Bryn (August 1974). "Chloroform: Commissions and Omissions". Proceedings of the Royal Society of Medicine. 67 (8): 723–730. doi:10.1177/003591577406700816. PMC 1645794 . PMID 4609043.
- ↑ Pearce, David (2008). "Chloroform". Utopian Surgery: Early arguments against anaesthesia in surgery, dentistry and childbirth. BLTC Research. Archived from the original on 2011-05-01. Retrieved 2010-12-24.
In 1864, the Report of Chloroform Committee of Royal Medical and Chirurgical Society endorsed chloroform as Britain's favourite anaesthetic. But ether was safer for patients.
- ↑ Wawersik, Juergen (1991). "History of Anesthesia in Germany". Journal of Clinical Anesthesia. 3 (3): 235–244. doi:10.1016/0952-8180(91)90167-L. PMID 1878238.
Chloroform committees and commissions | ||
|---|---|---|
| 1847 | (Chloroform first used) |  |
| 1864 | ||
| 1877 | ||
| 1888 |
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| 1889 |
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| 1891 | ||
| 1893 |
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| 1901 | ||
| 1912 |
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The list shown in this table is referenced.to view its references see: Template:Chloroform committees and commissions. | ||