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A cholekinetic drug is a pharmaceutical drug which increases the contractile power of the bile duct. [1]
| | This article needs additional citations for verification .(February 2024) |
A cholekinetic drug is a pharmaceutical drug which increases the contractile power of the bile duct. [1]
Cocaine is a tropane alkaloid that acts as a central nervous system (CNS) stimulant. As an extract, it is mainly used recreationally, and often illegally for its euphoric and rewarding effects. It is also used in medicine by Indigenous South Americans for various purposes and rarely, but more formally, as a local anaesthetic or diagnostic tool by medical practitioners in more developed countries. It is primarily obtained from the leaves of two Coca species native to South America: Erythroxylum coca and E. novogranatense. After extraction from the plant, and further processing into cocaine hydrochloride, the drug is administered by being either snorted, applied topically to the mouth, or dissolved and injected into a vein. It can also then be turned into free base form, in which it can be heated until sublimated and then the vapours can be inhaled.
3,4-Methyl
The United States Food and Drug Administration is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, prescription and over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, animal foods & feed and veterinary products.
Heroin, also known as diacetylmorphine and diamorphine among other names, is a morphinan opioid substance synthesized from the dried latex of the Papaver somniferum plant; it is mainly used as a recreational drug for its euphoric effects. Medical-grade diamorphine is used as a pure hydrochloride salt. Various white and brown powders sold illegally around the world as heroin are routinely diluted with cutting agents. Black tar heroin is a variable admixture of morphine derivatives—predominantly 6-MAM (6-monoacetylmorphine), which is the result of crude acetylation during clandestine production of street heroin. Heroin is used medically in several countries to relieve pain, such as during childbirth or a heart attack, as well as in opioid replacement therapy.
Oxycodone, sold under various brand names such as Roxicodone and OxyContin, is a semi-synthetic opioid used medically for treatment of moderate to severe pain. It is highly addictive and is a commonly abused drug. It is usually taken by mouth, and is available in immediate-release and controlled-release formulations. Onset of pain relief typically begins within fifteen minutes and lasts for up to six hours with the immediate-release formulation. In the United Kingdom, it is available by injection. Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin.
Pharmacology is a science of medical drug and medication, including a substance's origin, composition, pharmacokinetics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals.
Phencyclidine or phenylcyclohexyl piperidine (PCP), also known in its use as a street drug as angel dust among other names, is a dissociative anesthetic mainly used recreationally for its significant mind-altering effects. PCP may cause hallucinations, distorted perceptions of sounds, and violent behavior. As a recreational drug, it is typically smoked, but may be taken by mouth, snorted, or injected. It may also be mixed with cannabis or tobacco.
Fentanyl is a potent synthetic piperidine opioid primarily used as an analgesic. It is 50 times more potent than heroin and 100 times more potent than morphine; its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries. Fentanyl is also used as a sedative. Depending on the method of delivery, fentanyl can be very fast acting and ingesting a relatively small quantity can cause overdose. Fentanyl works by activating μ-opioid receptors. Fentanyl is sold under the brand names Actiq, Duragesic and Sublimaze, among others.
The Drug Enforcement Administration is a United States federal law enforcement agency under the U.S. Department of Justice tasked with combating illicit drug trafficking and distribution within the U.S. It is the lead agency for domestic enforcement of the Controlled Substances Act, sharing concurrent jurisdiction with the Federal Bureau of Investigation, the U.S. Immigration and Customs Enforcement, and U.S. Customs and Border Protection. However, the DEA has sole responsibility for coordinating and pursuing U.S. drug investigations both domestically and internationally.
A medication is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management.
The illegal drug trade, drug trafficking, or narcotrafficking is a global black market dedicated to the cultivation, manufacture, distribution and sale of prohibited drugs. Most jurisdictions prohibit trade, except under license, of many types of drugs through the use of drug prohibition laws. The think tank Global Financial Integrity's Transnational Crime and the Developing World report estimates the size of the global illicit drug market between US$426 and US$652 billion in 2014 alone. With a world GDP of US$78 trillion in the same year, the illegal drug trade may be estimated as nearly 1% of total global trade. Consumption of illegal drugs is widespread globally, and it remains very difficult for local authorities to reduce the rates of drug consumption.
The Medellín Cartel was a powerful and highly organized Colombian drug cartel and terrorist organization originating in the city of Medellín, Colombia, that was founded and led by Pablo Escobar. It is often considered to be the first major "drug cartel" and was referred to as such; due to the organization's upper echelons and overall power-structure being built on a partnership between multiple Colombian traffickers operating alongside Escobar. Included were Jorge Luis Ochoa Vásquez, Fabio Ochoa Vásquez, Juan David Ochoa Vásquez, José Gonzalo Rodríguez Gacha and Carlos Lehder. Escobar's main partner in the organization however was his cousin Gustavo Gaviria who handled much of the cartel's shipping arrangements and the more general and detailed logistical aspects of the cocaine trafficking routes and international smuggling networks which were supplying at least 80% of the world's cocaine during its peak. Gustavo, also known as León seems to have also had a strong hand in the cartel's unprecedented acts of narcoterrorism, right alongside his cousin Pablo and was considered to be second in command of the cartel and therefore one of Colombia's most wanted men, with both him and Escobar having arrest warrants pending from other nations where their criminal activity had spread to, such as in Spain and the U.S. Meanwhile, Pablo Escobar's brother Roberto Escobar acted as the organization's accountant. The cartel operated from 1976 to 1993 in Colombia (Antioquia), Bolivia, Panama, Central America, Peru, the Bahamas, the United States, as well as in Canada.
The war on drugs is the policy of a global campaign, led by the United States federal government, of drug prohibition, military aid, and military intervention, with the aim of reducing the illegal drug trade in the United States. The initiative includes a set of drug policies that are intended to discourage the production, distribution, and consumption of psychoactive drugs that the participating governments, through United Nations treaties, have made illegal.
Cannabis, also known as marijuana or weed among other names, is a psychoactive drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both recreational and entheogenic purposes and in various traditional medicines for centuries. Tetrahydrocannabinol (THC) is the main psychoactive component of cannabis, which is one of the 483 known compounds in the plant, including at least 65 other cannabinoids, such as cannabidiol (CBD). Cannabis can be used by smoking, vaporizing, within food, or as an extract.
Joaquín Archivaldo Guzmán Loera, commonly known as "El Chapo" and "JGL", is a Mexican former drug lord and a former leader within the Sinaloa Cartel, an international crime syndicate. He is considered to have been one of the most powerful drug traffickers in the world.
The Mexican drug war is an ongoing asymmetric low-intensity conflict between the Mexican government and various drug trafficking syndicates. When the Mexican military intervened in 2006, the government's main objective was to reduce drug-related violence. The Mexican government has asserted that their primary focus is dismantling the cartels and preventing drug trafficking. The conflict has been described as the Mexican theater of the global war on drugs, as led by the United States federal government.
A drug is any chemical substance that when consumed causes a change in an organism's physiology, including its psychology, if applicable. Drugs are typically distinguished from food and other substances that provide nutritional support. Consumption of drugs can be via inhalation, injection, smoking, ingestion, absorption via a patch on the skin, suppository, or dissolution under the tongue.
Methamphetamine is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. Methamphetamine was discovered in 1893 and exists as two enantiomers: levo-methamphetamine and dextro-methamphetamine. Methamphetamine properly refers to a specific chemical substance, the racemic free base, which is an equal mixture of levomethamphetamine and dextromethamphetamine in their pure amine forms, but the hydrochloride salt, commonly called crystal meth, is widely used. Methamphetamine is rarely prescribed over concerns involving human neurotoxicity and potential for recreational use as an aphrodisiac and euphoriant, among other concerns, as well as the availability of safer substitute drugs with comparable treatment efficacy such as Adderall and Vyvanse. Dextromethamphetamine is a stronger CNS stimulant than levomethamphetamine.
The Sinaloa Cartel, also known as the Guzmán-Zambada Organization, the Federation, the Blood Alliance, or the Pacific Cartel, is a large, international organized crime syndicate based in the city of Culiacán, Sinaloa, that specializes in illegal drug trafficking and money laundering. It was established in Mexico during the late 1980s as one of a various number of subordinate "plazas" operating under a predecessor organization known as the Guadalajara Cartel. It is currently headed by Ismael Zambada García and is based in the city of Culiacán, Sinaloa, with operations in many world regions but primarily in the Mexican states of Sinaloa, Baja California, Durango, Sonora, and Chihuahua. and presence in a number of other regions in Latin America as well as in cities across the U.S. The United States Intelligence Community generally considers the Sinaloa Cartel to be the largest and most powerful drug trafficking organization in the world, making it perhaps even more influential and capable than Pablo Escobar's infamous Medellín Cartel of Colombia was during its prime. According to the National Drug Intelligence Center and other sources within the U.S. the Sinaloa Cartel is primarily involved in the distribution of cocaine, heroin, methamphetamine, fentanyl, cannabis and MDMA.
A drug lord, drug baron, kingpin, or lord of drugs is a type of crime boss, who is in charge of a drug-trafficking network, organization, or enterprise.
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