Chondroitin

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A chondroitin, as the sulfate, is a component of bamacan, a proteoglycan (sugar-protein conjugate) that comprises some membranes. [1] Condroitin is a chondrin derivative. [2]

Types include:

Chondroitin as a supplement is now commonly used (often in combination with glucosamine) in treating the joint disease of osteoarthritis. [3] In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in the patient which it can be used as an alternative medicine. [3] Chondroitin's effect toward the articular cartilage integrity as it is part of the proteoglycan molecules. [4] The cartilage proteoglycan synthesis can speed up as chondroitin is going through the pathway of the alimentary canal. [4] Research has been conducted to show the effectiveness of chondroitin and results indicate that it helps to manage pain in knee and hip, slow down the progression and also recovery. [5] However, the effectiveness of the drugs is still doubtful. [4]

References

  1. Iozzo, Renato V. (1998). "MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function". Annual Review of Biochemistry. 67: 609–652. doi:10.1146/annurev.biochem.67.1.609. PMID   9759499.
  2. Chondroitin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
  3. 1 2 Vasiliadis, Haris S; Tsikopoulos, Konstantinos (2017). "Glucosamine and chondroitin for the treatment of osteoarthritis". World Journal of Orthopedics. 8 (1): 1–11. doi: 10.5312/wjo.v8.i1.1 . ISSN   2218-5836. PMC   5241539 . PMID   28144573.
  4. 1 2 3 Tavakol, Kamran. "Glucosamine and Chondroitin for Treatment of Osteoarthritis: A Systematic Quality Assessment and Meta-analysis". Physical Therapy. 80 (10): 1049.
  5. Zhu, Xiaoyue; Sang, Lingli; Wu, Dandong; Rong, Jiesheng; Jiang, Liying (December 2018). "Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials". Journal of Orthopaedic Surgery and Research. 13 (1): 170. doi: 10.1186/s13018-018-0871-5 . ISSN   1749-799X. PMC   6035477 . PMID   29980200.