Claudius Regaud

Last updated
Claudius Regaud
Claudius Regaud.png
Born(1870-01-30)January 30, 1870
DiedDecember 29, 1940(1940-12-29) (aged 70)
Nationality French
Occupation(s)Doctor and Biologist
Known forFounder of the Curie Institute of Paris

Claudius Regaud (born 30 January 1870 in Lyons, France; died 29 December 1940 in Couzon-au-Mont-d'Or, France) was a French medical doctor and biologist, one of the pioneers in radiotherapy at the Curie Institute.

Scientific work

In 1906, Regaud discovered that one of the effects of X-ray treatment is sterility. He deduced that X-rays could also be used against rapidly growing cells other than gametes and, thus, against cancerous tumors. [1] He proceeded to conduct the first experiments in this area. [2] In 1912, at the Curie Institute, he was given responsibility for the Pasteur Laboratory, with the mission to study the biological and medical effects of radioactivity. The Curie laboratory, in contrast, dealt with research in the fields of physics and chemistry. [3]

In addition, he started a program to fight neoplasia and conducted research to determine the optimal duration and dosage for radiation therapy. [4]

Related Research Articles

<span class="mw-page-title-main">Marie Curie</span> Polish-French physicist and chemist (1867–1934)

Marie Salomea Skłodowska–Curie was a Polish and naturalized-French physicist and chemist who conducted pioneering research on radioactivity. She was the first woman to win a Nobel Prize, the first person to win a Nobel Prize twice, and the only person to win a Nobel Prize in two scientific fields. Her husband, Pierre Curie, was a co-winner of her first Nobel Prize, making them the first-ever married couple to win the Nobel Prize and launching the Curie family legacy of five Nobel Prizes. She was, in 1906, the first woman to become a professor at the University of Paris.

<span class="mw-page-title-main">Pierre Curie</span> French physicist (1859–1906)

Pierre Curie was a French physicist, a pioneer in crystallography, magnetism, piezoelectricity, and radioactivity. In 1903, he received the Nobel Prize in Physics with his wife, Marie Skłodowska–Curie, and Henri Becquerel, "in recognition of the extraordinary services they have rendered by their joint researches on the radiation phenomena discovered by Professor Henri Becquerel". With their win, the Curies became the first ever married couple to win the Nobel Prize, launching the Curie family legacy of five Nobel Prizes.

<span class="mw-page-title-main">Henri Becquerel</span> French physicist and engineer (1852–1908)

Antoine Henri Becquerel was a French engineer, physicist, Nobel laureate, and the first person to discover evidence of radioactivity. For work in this field he, along with Marie Skłodowska-Curie and Pierre Curie, received the 1903 Nobel Prize in Physics. The SI unit for radioactivity, the becquerel (Bq), is named after him.

<span class="mw-page-title-main">Irène Joliot-Curie</span> French scientist (1897–1956)

Irène Joliot-Curie was a French chemist, physicist and politician, the elder daughter of Pierre Curie and Marie Skłodowska–Curie, and the wife of Frédéric Joliot-Curie. Jointly with her husband, Joliot-Curie was awarded the Nobel Prize in Chemistry in 1935 for their discovery of induced radioactivity, making them the second-ever married couple to win the Nobel Prize, while adding to the Curie family legacy of five Nobel Prizes. This made the Curies the family with the most Nobel laureates to date. She was also one of the first three women to be a member of a French government, becoming undersecretary for Scientific Research under the Popular Front in 1936. Both children of the Joliot-Curies, Hélène and Pierre, are also prominent scientists.

<span class="mw-page-title-main">Curie Institute (Paris)</span> French scientific research center

Institut Curie is one of the leading medical, biological and biophysical research centres in the world. It is a private non-profit foundation operating a research center on biophysics, cell biology and oncology and a hospital specialized in treatment of cancer. It is located in Paris, France.

Harold Elford Johns was a Canadian medical physicist, noted for his extensive contributions to the use of ionizing radiation to treat cancer.

Induced radioactivity, also called artificial radioactivity or man-made radioactivity, is the process of using radiation to make a previously stable material radioactive. The husband and wife team of Irène Joliot-Curie and Frédéric Joliot-Curie discovered induced radioactivity in 1934, and they shared the 1935 Nobel Prize in Chemistry for this discovery.

<span class="mw-page-title-main">William Duane (physicist)</span> American physicist

William Duane was an American physicist who conducted research on radioactivity and X-rays and their usage in the treatment of cancer. He developed the Duane-Hunt Law and Duane's hypothesis. He worked with Pierre and Marie Curie in their University of Paris laboratory for six years and developed a method for generating quantities of radon-222 "seeds" from radium for usage in early forms of brachytherapy.

Sir Stanford Cade, was a British surgeon of Russian origin, who pioneered the combined use of surgery and radiotherapy in the treatment of cancer in England. He was born in what was then the Russian Empire, educated in Antwerp, and started his medical training in Brussels. His training was interrupted by the First World War, and he was evacuated to England. Cade's medical education continued at Westminster Hospital Medical School, and following qualification he did various jobs at Westminster Hospital, finally being appointed consultant surgeon. He pioneered the combined use of radium or X rays in the treatment of cancer. During the Second World War, Cade was a member of the Royal Air Force Volunteer Reserve. In addition to his medical work, he also advised on improvements in the design of the cockpits of fighter planes, for which he was awarded a knighthood. After the war, Cade's work led to him gaining several honours and appointments. Cade wrote two books on the treatment of cancer.

<span class="mw-page-title-main">Horia Hulubei</span> Romanian nuclear physicist

Horia Hulubei was a Romanian nuclear physicist, known for his contributions to the development of X-ray spectroscopy.

Maurice Lenz was a pioneer in the field of radiation therapy. Born in Kovno, Russian Empire, Lenz studied at New York University and Bellevue Medical College, and received his medical degree from Columbia University College of Physicians and Surgeons in 1913. He was a professor of radiation oncology at the Columbia University College of Physicians and Surgeons, a past president of the American Radium Society and held many other clinical and administrative roles throughout a long career in medicine.

<span class="mw-page-title-main">Yvette Cauchois</span> French physicist

Yvette Cauchois was a French physicist known for her contributions to x-ray spectroscopy and x-ray optics, and for pioneering European synchrotron research.

The history of radiation therapy or radiotherapy can be traced back to experiments made soon after the discovery of X-rays (1895), when it was shown that exposure to radiation produced cutaneous burns. Influenced by electrotherapy and escharotics — the medical application of caustic substances — doctors began using radiation to treat growths and lesions produced by diseases such as lupus, basal cell carcinoma, and epithelioma. Radiation was generally believed to have bactericidal properties, so when radium was discovered, in addition to treatments similar to those used with x-rays, it was also used as an additive to medical treatments for diseases such as tuberculosis where there were resistant bacilli.

Jean-François Rossignol is a French scientist, a medicinal chemist and a physician, born in France on September 5, 1943. He was educated at the University of Paris, later specializing in tropical medicine. He then pursued a career in academia and in the pharmaceutical industry discovering and developing new drugs for the treatment of parasitic diseases such as halofantrine in the treatment of multidrug resistant Falciparum malaria or albendazole and nitazoxanide for the treatment of intestinal protozoan and helminthic infections. In 1993, he co-created his own pharmaceutical company, Romark Laboratories, L.C., to develop his own invention nitazoxanide, the first of the thiazolides. At Romark, he is the Chairman of the Board of Directors of the company and its Chief Science Officer. Following the discovery of the antiviral activity of the thiazolides Rossignol went to Stanford University in California to study interferon stimulated gene pathways and chronic viral hepatitis under Prof. Emmet Keeffe and Prof. Jeffery Glenn. It was in the Glenn laboratory that the mechanism of antiviral activity of nitazoxanide against the hepatitis C virus was discovered.

<span class="mw-page-title-main">Ștefania Mărăcineanu</span> Romanian physicist (1882–1944)

Ștefania Mărăcineanu was a Romanian physicist. She worked with Marie Curie studying the element named for Curie's homeland Polonium. She made proposals that would lead to Irène Joliot-Curie's Nobel Prize. Mărăcineanu believed that Joliot-Curie had taken her work on Induced radioactivity to gain the prize.

<span class="mw-page-title-main">Álvaro Alvim</span>

Álvaro Freire de Villalba Alvim was a Brazilian physician, pioneer in radiology and radiotherapy. He studied in France with Pierre and Marie Curie and performed the first radiograph in Brazil, which was on the xiphopagus case for Brazilian surgeon Eduardo Chapot Prévost.

Léon Zadoc-Kahn was a French doctor, the Chief Medical Officer of the Rothschild Hospital, Paris, treasurer of the Curie Foundation and the Chair of the Central Committee of Keren haYesod, France. During the time of Vichy France, he was arrested and transported with his wife from his homeland to Auschwitz Concentration Camp where they were murdered.

Alain-Jacques Valleron (born 24 August 1943 in Neuilly-sur-Seine is Professor Emeritus at the Pierre-et-Marie-Curie University and a member of the French Academy of sciences, of which he was Delegate for Scientific Information and Communication. He is the founder of the "Sentinel Network".

<span class="mw-page-title-main">Henri Coutard</span> French radiation therapist

Henri Coutard was a French radiation therapist. He is known for his studies of radiation therapy for the treatment of laryngeal cancer and the development of the "protracted-fractional method" of radiation dosing.

Marie Curie, une femme sur le front is a Franco-Belgian drama historical television film directed by Alain Brunard and starring Dominique Reymond. It was broadcast on April 25, 2014 on RTBF and November 11, 2014 on France 2.

References

  1. "Portrait de Médecins" [Portraits of Physicians]. Medarus (in French). Archived from the original on 10 September 2013. Retrieved 25 April 2014.
  2. Prigent, Anne (10 August 2012). "Marie Curie à l'origine de la radiothérapie" [Marie Curie on the origin of radiotherapy]. Le Figaro (in French). Retrieved 25 April 2014.
  3. "2009, Centenaire de l'Institut Curie" [2009: Centenary of the Curie Institute]. Curie Institute of Paris (in French). 8 June 2010. Archived from the original on 25 July 2014. Retrieved 25 April 2014.
  4. "Claudius Regaud (1870-1940)" (in French). Musée Curie . Retrieved 25 April 2014.