DNA Solutions is a DNA testing company [1] created by biotechnologist Vern Muir B.Sc. in 1996, and incorporated in 1998. The company created a home paternity kit in 1997 and has since expanded its services to include DNA sample storage.
DNA Solutions created the 'home paternity kit' in 1997, which was a new concept where people for the first time could take samples for DNA testing at home, instead of in the laboratory. Originally the kits worked by people taking a hair sample, and posting into the laboratory for testing. The kit was first reported in the Australian newspaper The Herald in 1998.
These home testing kits have since revolutionized DNA testing,[ citation needed ] and the industry has subsequently adopted DNA Solutions' terminology of using "home kit" and "home paternity kit" a term now used by virtually all DNA testing companies and laboratories for the "use at home" DNA testing services.
This new type of DNA testing led to a great deal of controversy, especially in the year 2000, when the Vice President of the Australian Medical Association issued a press releasing calling for a ban of DNA Solutions's services due to issues of privacy and consent. [2] News of the new tests, and their availability online spread worldwide [3] [4]
Over the next decade while DNA testing kits were being adopted by most DNA laboratories, DNA Solutions spread its services to such countries as Russia, France and China. [5] [6] [7]
In 2007, DNA Solutions profiled 800 elephant dung samples from the jungles of Cambodia in order to calculate the number of wild elephants remaining in the wild. [8]
In 2008, DNA Solutions won the tender to store DNA samples for the Australian military and at the same time launched a service to store DNA samples for the public. [9]
DNA Solutions offers the analysis of Y-DNA for identification geographic and ethnic origin [10] of paternal lineage. The use of Y-DNA testing is useful for discerning biological relationships between people with the alleged same paternal lineage (i.e. Uncle-nephew, or grandfather-grandson DNA testing).
DNA Solutions offers the analysis of mitochondrial DNA (mtDNA); whilst only inherited maternally, mtDNA is found in both men and women. DNA Solutions sequences both the HVR1 and HVR2 regions for maternal ancestral and ethnic analysis. Mt-DNA testing is also used for proving biological relationships (i.e. cousins, granddaughter-grandmother, etc.)
DNA Solutions offers analysis of autosomal DNA STRs used for DNA profiling, paternity testing and other biological relationship tests, such as sibling tests.
DNA profiling is the process of determining an individual's deoxyribonucleic acid (DNA) characteristics. DNA analysis intended to identify a species, rather than an individual, is called DNA barcoding.
DNA paternity testing is the use of DNA profiles to determine whether an individual is the biological parent of another individual. Paternity testing can be especially important when the rights and duties of the father are in issue and a child's paternity is in doubt. Tests can also determine the likelihood of someone being a biological grandparent. Though genetic testing is the most reliable standard, older methods also exist, including ABO blood group typing, analysis of various other proteins and enzymes, or using human leukocyte antigen antigens. The current techniques for paternity testing are using polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP). Paternity testing can now also be performed while the woman is still pregnant from a blood draw.
Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, or through biochemical analysis to measure specific protein output. In a medical setting, genetic testing can be used to diagnose or rule out suspected genetic disorders, predict risks for specific conditions, or gain information that can be used to customize medical treatments based on an individual's genetic makeup. Genetic testing can also be used to determine biological relatives, such as a child's biological parentage through DNA paternity testing, or be used to broadly predict an individual's ancestry. Genetic testing of plants and animals can be used for similar reasons as in humans, to gain information used for selective breeding, or for efforts to boost genetic diversity in endangered populations.
Archaeogenetics is the study of ancient DNA using various molecular genetic methods and DNA resources. This form of genetic analysis can be applied to human, animal, and plant specimens. Ancient DNA can be extracted from various fossilized specimens including bones, eggshells, and artificially preserved tissues in human and animal specimens. In plants, ancient DNA can be extracted from seeds and tissue. Archaeogenetics provides us with genetic evidence of ancient population group migrations, domestication events, and plant and animal evolution. The ancient DNA cross referenced with the DNA of relative modern genetic populations allows researchers to run comparison studies that provide a more complete analysis when ancient DNA is compromised.
Genetic genealogy is the use of genealogical DNA tests, i.e., DNA profiling and DNA testing, in combination with traditional genealogical methods, to infer genetic relationships between individuals. This application of genetics came to be used by family historians in the 21st century, as DNA tests became affordable. The tests have been promoted by amateur groups, such as surname study groups or regional genealogical groups, as well as research projects such as the Genographic Project.
Forensic identification is the application of forensic science, or "forensics", and technology to identify specific objects from the trace evidence they leave, often at a crime scene or the scene of an accident. Forensic means "for the courts".
A genealogical DNA test is a DNA-based genetic test used in genetic genealogy that looks at specific locations of a person's genome in order to find or verify ancestral genealogical relationships, or to estimate the ethnic mixture of an individual. Since different testing companies use different ethnic reference groups and different matching algorithms, ethnicity estimates for an individual vary between tests, sometimes dramatically.
Forensic biology is a branch of forensics where biology is applied to associate a person — whether suspect or victim, to a location, an item, another person.
Paternity fraud, also known as misattributed paternity or paternal discrepancy, occurs when a man is incorrectly identified as the biological father of a child. The underlying assumption of "paternity fraud" is that the mother deliberately misidentified the biological father, while "misattributed paternity" may be accidental.
New England Biolabs (NEB) produces and supplies recombinant and native enzyme reagents for the life science research, as well as providing products and services supporting genome editing, synthetic biology and next-generation sequencing. NEB also provides free access to research tools such as REBASE, InBASE, and Polbase.
FamilyTreeDNA is a division of Gene by Gene, a commercial genetic testing company based in Houston, Texas. FamilyTreeDNA offers analysis of autosomal DNA, Y-DNA, and mitochondrial DNA to individuals for genealogical purpose. With a database of more than two million records, it is the most popular company worldwide for Y-DNA and mitochondrial DNA, and the fourth most popular for autosomal DNA. In Europe, it is the most common also for autosomal DNA. FamilyTreeDNA as a division of Gene by Gene were acquired by MYDNA, Inc., an Australian company, in January 2021.
A DNA database or DNA databank is a database of DNA profiles which can be used in the analysis of genetic diseases, genetic fingerprinting for criminology, or genetic genealogy. DNA databases may be public or private, the largest ones being national DNA databases.
The Sorenson Molecular Genealogy Foundation (SMGF) was an independent DNA and genealogical research institution with the goal of demonstrating how the peoples of the world are related. SMGF collected DNA samples and genealogical information from individuals across the globe to establish these connections.
Laboratory Corporation of America Holdings, more commonly known as Labcorp, is an American healthcare company headquartered in Burlington, North Carolina. It operates one of the largest clinical laboratory networks in the world, with a United States network of 36 primary laboratories. Before a merger with National Health Laboratory in 1995, the company operated under the name Roche BioMedical. Labcorp performs its largest volume of specialty testing at its Center for Esoteric Testing in Burlington, North Carolina, where the company is headquartered. As of 2018, Labcorp processes 2.5 million lab tests weekly.
BRT Laboratories, Inc. is a Baltimore, Maryland-based biotechnology company that performs DNA testing. The company has three divisions: Relationship Testing, Forensics, and Clinical Services. It is a privately held, wholly owned subsidiary of Baltimore RH Typing Laboratory, Inc.
GeneTree was a family history website focused on using DNA testing to trace ancestry. A website account was free, and within their account users could order DNA tests, enter results from other testing companies, search the DNA database, create an online family tree, and correspond with family members – including sharing pictures.
In paternity testing, Paternity Index (PI) is a calculated value generated for a single genetic marker or locus and is associated with the statistical strength or weight of that locus in favor of or against parentage given the phenotypes of the tested participants and the inheritance scenario. Phenotype typically refers to physical characteristics such as body plan, color, behavior, etc. in organisms. However, the term used in the area of DNA paternity testing refers to what is observed directly in the laboratory. Laboratories involved in parentage testing and other fields of human identity employ genetic testing panels that contain a battery of loci each of which is selected due to extensive allelic variations within and between populations. These genetic variations are not assumed to bestow physical and/or behavioral attributes to the person carrying the allelic arrangement(s) and therefore are not subject to selective pressure and follow Hardy Weinberg inheritance patterns.
Institute for Genetic Engineering and Biotechnology (INGEB) is a Bosnian public research institute, member of Sarajevo University (UNSA), and affiliate center of International Centre for Genetic Engineering and Biotechnology (ICGEB).
DNA profiling is the determination of a DNA profile for legal and investigative purposes. DNA analysis methods have changed numerous times over the years as technology improves and allows for more information to be determined with less starting material. Modern DNA analysis is based on the statistical calculation of the rarity of the produced profile within a population.