Daniel O. Griffin

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Daniel O. Griffin
Dr. Daniel O. Griffin.jpg

Daniel O'Connell Griffin (born 15 July 1967) is an American physician-scientist and infectious disease specialist. He is president of the nonprofit organization Parasites Without Borders, Chief of the Division of Infectious Disease at Island Infectious Disease Medical, and former Chief of Infectious Disease at Optum Tri-State. [1]

Contents

Griffin is also an instructor of clinical medicine at Columbia University Irving Medical Center and a former associate research scientist in its Department of Biochemistry and Molecular Biophysics. He is board-certified in Internal Medicine and Infectious Disease, and holds certification in Travel Medicine (CTH) and Clinical Tropical Medicine (CTropMed).

Education

Griffin earned his BA in Philosophy from the University of Colorado Boulder in 1989. [2] [3] He received his MD degree [4] from New York University School of Medicine and completed an internal medicine residency at the University of Utah. [4] He completed a PhD in Molecular medicine from the Elmezzi Graduate School of Molecular Medicine, Manhasset, New York in 2012. [5] In 2014, he completed a fellowship in infectious diseases from North Shore-Long Island Jewish Health System-Hofstra University in Manhasset. [6]

He also completed a Certificate in the Business of Medicine at the Johns Hopkins Carey Business School in 2000, and an ASTMH-approved course in Clinical Tropical Medicine and Travel Medicine through the University of Minnesota in 2016. [6] [7]

Research and career

Griffin is a co-director of the life science podcast network Microbe.TV, where he co-hosts several shows, including This Week in Virology (TWiV), This Week in Parasitism, and The Infectious Disease Puscast. [8] His weekly COVID Clinical Update podcast has been cited for its role in translating emerging clinical knowledge during the pandemic. [9]

Griffin co-authored the textbook Parasitic Diseases (7th edition 2019), [10] [11] available in more than 100 countries. In 2017, he published the paper Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70 in the Journal of Experimental Medicine. He also contributed chapters to major infectious disease texts, including the AAP Red Book (2021, 2024, and 2027 editions) and Elsevier's Textbook of SARS-CoV-2 and COVID-19 (2023). [12]

He is senior fellow in infectious disease at United Health Group, [13] Instructor in Clinical Medicine, Columbia University Irving Medical Centre, and Infectious Disease Clinician Chief, Pro Health Care. [7]

Griffin's work includes investigating the potential role of human B1 cells and natural antibodies in the development of HIV-associated malignancies. [4] [14] He has a special focus on HIV and tropical medicine. [15] His research interests are broad and include studies on infectious disease and immunology, molecular medicine, and tropical medicine.[ citation needed ] As of 2021, his research focused on HIV-1, stem cell latency, stem cell gene therapy using retroviral vectors, and COVID-19. [16] [17] He has since published extensively on Long COVID, COVID-19 vaccine effectiveness, monoclonal antibody therapies, and public health policy. Notable recent publications have appeared in Nature Communications, BMJ Open, Open Forum Infectious Diseases, and Blood Advances.

Griffin has volunteered with the nonprofit Foundation for International Medical Relief of Children, including conducting mandatory health education sessions for its staff. [18] [19] [20] He joined the biomedical research community of the Vagelos College of Physicians and Surgeons of Columbia University.[ citation needed ] He is an associate research scientist in Columbia's Department of Biochemistry and Molecular Biophysics, instructor of clinical medicine, and a member of the division of infectious diseases. [21] [4]

Science communication

Griffin co-authored at least two editions of a textbook on parasitology, Parasitic Diseases, with Dickson Despommier. [22] The two men decided to found the nonprofit organization Parasites Without Borders to disseminate clinical information about parasitic disease, including the textbook. [23] [24] [22] [25] As of June 2021, 40,000 copies had been distributed to over 100 countries. [25]

He has co-hosted This Week in Parasitism since episode 80 and joined This Week in Virology in March 2020 to deliver weekly clinical updates on COVID-19. He later became a host of The Infectious Disease Puscast, further expanding his public engagement in infectious disease education. [26]

In early March 2020 as the COVID-19 pandemic began to seriously affect the New York City area, Griffin began providing clinical updates about the virus based on his practice and correspondence with medical colleagues around the world on another podcast hosted by Racaniello, This Week in Virology (TWiV). [27] Eventually the popularity of the clinical updates resulted in Racaniello publishing them in standalone episodes of TWiV. [28] As of May 2022, Griffin had provided 112 such clinical updates on TWiV. [9]

In 2024, he gave keynote addresses for the Maine Medical Association and the Taiwanese Medical Association, and spoke at the Asia Pacific Regional Conference of WONCA in Singapore.

Affiliations

Griffin is a member in the following scientific societies or associations:

Patents

Griffin is co-inventor on the patent "Human B1 cells and uses thereof," issued in 2013. [31]

Awards

Selected publications

References

  1. "Education for Parasitic Diseases | Parasites Without Borders". parasiteswithoutborders.com. 5 February 2020. Retrieved 2022-05-02.
  2. "Notes from the Class of 1989". Alumni Association. Retrieved 2022-05-01.
  3. ecropolis (2020-02-05). "Daniel Griffin, MD, PhD | Parasites without Borders" . Retrieved 2022-05-01.
  4. 1 2 3 4 5 "Daniel Griffin, M.D., Ph.D." ASM.org. Retrieved 2022-05-01.
  5. "Elmezzi Graduate School of Molecular Medicine". The Elmezzi Foundation. Retrieved 2022-05-01.
  6. 1 2 "Dr. Daniel Griffin, MD – Lake Success, NY | Infectious Disease on Doximity". Doximity. Retrieved 2021-02-04.
  7. 1 2 "Daniel Griffin, MD". www.prohealthcare.com. Retrieved 2022-05-02.
  8. "The Latest Podcasts in the Microbe.TV Network". 2015-12-01. Retrieved 2022-05-02.
  9. 1 2 "TWiV 895: COVID-19 clinical update #112 with Dr. Daniel Griffin". 2022-04-30. Retrieved 2022-05-02.
  10. Griffin, Daniel; Gwadz, Robert; DESPOMMIER, DICKSON; Hotez, Peter; Knirsch, Charles (2017-03-25). Parasitic Diseases 6th Edition. Independently Published. ISBN   978-1-5208-8997-9.
  11. ecropolis (2020-02-05). "Books | Parasites without Borders" . Retrieved 2022-05-02.
  12. Griffin, Daniel O.; Holodick, Nichol E.; Rothstein, Thomas L. (2011-01-17). "Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70−". The Journal of Experimental Medicine. 208 (1): 67–80. doi:10.1084/jem.20101499. ISSN   0022-1007. PMC   3023138 . PMID   21220451.
  13. "Antibody Research & Treatment: How We're Fighting COVID-19". www.unitedhealthgroup.com. Retrieved 2022-05-02.
  14. 1 2 Rothstein, Thomas L.; Griffin, Daniel O.; Holodick, Nichol E.; Quach, Tam D.; Kaku, Hiroaki (May 2013). "Human B-1 cells take the stage". Annals of the New York Academy of Sciences. 1285 (1): 97–114. Bibcode:2013NYASA1285...97R. doi:10.1111/nyas.12137. ISSN   1749-6632. PMC   4429725 . PMID   23692567.
  15. "Bio". www.diabetestechnology.org. Retrieved 2021-02-04.
  16. Ngo, Binh T.; Marik, Paul; Kory, Pierre; Shapiro, Leland; Thomadsen, Raphael; Iglesias, Jose; Ditmore, Stephen; Rendell, Marc; Varon, Joseph; Dubé, Michael; Nanda, Neha (2021-01-23). "The time to offer treatments for COVID-19". pp. 505–518. medRxiv   10.1101/2020.05.27.20115238v9 .
  17. Griffin, Daniel O.; Rothstein, Thomas L. (2012). "Human b1 cell frequency: isolation and analysis of human b1 cells". Frontiers in Immunology. 3: 122. doi: 10.3389/fimmu.2012.00122 . ISSN   1664-3224. PMC   3360193 . PMID   22654880.
  18. "Parasites Without Borders Creates Pop-Up Fundraiser for FIMRC". www.fimrc.org. Retrieved 2022-05-01.
  19. "Uganda Volunteer". www.fimrc.org. Retrieved 2022-05-01.
  20. "Celebrating World NTD Day". www.fimrc.org. Retrieved 2022-05-01.
  21. "Columbia University: Directory". directory.columbia.edu. Retrieved 2022-05-01.
  22. 1 2 Rosenthal, Philip J. (2018-03-07). "Book Review". The American Journal of Tropical Medicine and Hygiene. 98 (3): 933–934. doi:10.4269/ajtmh.17-1003. ISSN   0002-9637. PMC   5930926 .
  23. Borders, Parasites Without. "Directors of Parasites Without Borders Helping Fight COVID-19". www.prnewswire.com (Press release). Retrieved 2022-05-01.
  24. "Parasites Without Borders Inc". IRS. 1 May 2022. Retrieved 1 May 2022.
  25. 1 2 "ASTMH - Q&A with Parasites Without Borders". www.astmh.org. Retrieved 2022-05-02.
  26. "TWiP 80: Daniel in the parasites' den | This Week in Parasitism". 2015-01-08. Retrieved 2022-05-02.
  27. "TWiV Special: Coronavirus SARS-CoV-2 and COVID-19 update | This Week in Virology". 2020-03-05. Retrieved 2022-05-02.
  28. "TWiV 686: COVID-19 clinical update #38 with Dr. Daniel Griffin | This Week in Virology". 2020-11-28. Retrieved 2022-05-02.
  29. "2016 Cerficiate of Tropical Medicine Recipients" (PDF). American Society of Tropical Medicine and Hygiene. 2 May 2022. Retrieved 2 May 2022.
  30. "The International Society of Travel Medicine". www.istm.org. Retrieved 2022-05-02.
  31. CA 2812416,Rothstein, Thomas L.; Griffin, Daniel O.& Holodick, Nichol E.,"Human B1 cells and uses thereof",published 2012-03-29,issued 2011-09-22, assigned to The Feinstein Institute for Medical Research
  32. "Northwell Health Foundation". support.northwell.edu. Retrieved 2021-02-04.
  33. "Daniel Griffin, MD, HIMSS 2006 Davies award for excellence in Electronic Medical Records | EMR Software | Praxis EMR, EHR Software". www.praxisemr.com. Retrieved 2021-02-04.
  34. "Providers". Optum - Health Services Innovation Company. Retrieved 2025-05-14.
  35. "malcolm baldrige quality: Topics by Science.gov". www.science.gov. Retrieved 2025-05-14.
  36. Grady, Connor B.; Bhattacharjee, Bornali; Silva, Julio; Jaycox, Jillian; Lee, Lik Wee; Silva Monteiro, Valter; Sawano, Mitsuaki; Massey, Daisy; Caraballo, César; Gehlhausen, Jeff R.; Tabachnikova, Alexandra; Mao, Tianyang; Lucas, Carolina; Peña-Hernandez, Mario A.; Xu, Lan (2025-05-09). "Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naïve individuals with Long COVID". Communications Medicine. 5 (1): 163. doi:10.1038/s43856-025-00829-3. ISSN   2730-664X. PMC   12064684 . PMID   40346201.
  37. Griffin, Daniel O. (September 2024). "Postacute Sequelae of COVID (PASC or Long COVID): An Evidenced-Based Approach". Open Forum Infectious Diseases. 11 (9) ofae462. doi:10.1093/ofid/ofae462. ISSN   2328-8957. PMC   11363684 . PMID   39220656.
  38. Griffin, Daniel; McNeil, Chace; Okusa, James; Berrent, Diana; Guo, Yinglong; Daugherty, Sarah E. (2023-08-08). "Does monoclonal antibody treatment for COVID-19 impact short and long-term outcomes in a large generalisable population? A retrospective cohort study in the USA". BMJ Open. 13 (8) e069247. doi:10.1136/bmjopen-2022-069247. ISSN   2044-6055. PMC   10414114 . PMID   37553188.
  39. Griffin, Daniel O.; Holodick, Nichol E.; Rothstein, Thomas L. (2011-01-17). "Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70−". Journal of Experimental Medicine. 208 (1): 67–80. doi:10.1084/jem.20101499. ISSN   0022-1007. PMC   3023138 . PMID   21220451.
  40. Lyng, Gregory D.; Sheils, Natalie E.; Kennedy, Caleb J.; Griffin, Daniel; Berke, Ethan M. (2020-10-12). "Identifying Optimal COVID-19 Testing Strategies for Schools and Businesses: Balancing Testing Frequency, Individual Test Technology, and Cost". medRxiv   10.1101/2020.10.11.20211011v2 .
  41. Griffin, Daniel O.; Rothstein, Thomas L. (2011-12-19). "A small CD11b+ human B1 cell subpopulation stimulates T cells and is expanded in lupus". Journal of Experimental Medicine. 208 (13): 2591–2598. doi:10.1084/jem.20110978. ISSN   0022-1007. PMC   3244038 . PMID   22110167.
  42. Griffin, Daniel O.; Rothstein, Thomas L. (June 2012). "Human "Orchestrator" CD11b + B1 Cells Spontaneously Secrete Interleukin-10 and Regulate T-Cell Activity". Molecular Medicine. 18 (6): 1003–1008. doi:10.2119/molmed.2012.00203. ISSN   1528-3658. PMC   3459484 . PMID   22634719.
  43. Griffin, Daniel; Rothstein, Thomas L. (2012). "Human B1 Cell Frequency: Isolation and Analysis of Human B1 Cells". Frontiers in Immunology. 3: 122. doi: 10.3389/fimmu.2012.00122 . ISSN   1664-3224. PMC   3360193 . PMID   22654880.
  44. Griffin, Daniel O.; Holodick, Nichol E.; Rothstein, Thomas L. (2011-12-19). "Human B1 cells are CD3−: A reply to "A human equivalent of mouse B-1 cells?" and "The nature of circulating CD27+CD43+ B cells"". Journal of Experimental Medicine. 208 (13): 2566–2569. doi:10.1084/jem.20111761. ISSN   0022-1007. PMC   3244032 . PMID   22184682.