Deutsche Sammlung von Mikroorganismen und Zellkulturen

Last updated
Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH
AbbreviationDSMZ
PredecessorCollection of Microorganisms Göttingen (SMG)
Merged intoGerman Collection of Microorganisms (DSM)
Formation1969
TypeIndependent, non-profit organization
PurposeNational culture collection
Location
Fields Microbiology, Cell Biology
LeaderJörg Overmann (scientific director), Bettina Fischer (administrative director)
Affiliations Leibniz Association
Staff
192 (status: December 2020)
Website www.dsmz.de

The Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH (German: Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH), located in Braunschweig, is a research infrastructure in the Leibniz Association. Also the DSMZ is the world's most diverse collection [1] of bioresources (status 2021: 75,000 bioresources). [2] These include microorganisms (including more than 32,000 bacterial strains, 690 archaeal strains, 7,000 strains of yeasts and fungi) as well as more than 840 human and animal cell cultures, over 1. 500 plant viruses, over 940 bacteriophages, and 250 plasmids (status 2021). [3] Since 2010, the scientific director of the Leibniz Institute DSMZ has been Jörg Overmann, a microbiologist with a PhD. [4] He holds a professorship in microbiology at the Technical University of Braunschweig. [5] Since August 2018, he has led the institute in a dual leadership with Bettina Fischer as administrative director. [6]

Contents

History

YearEvent
1969Establishment Collection of Microorganisms Göttingen (SMG) in the Department of Nutritional Physiology of Microorganisms with Microbial Bank (Administrative Head D. Claus) at the Göttingen Institute of Microbiology of the Society for Radiation Research
1973Official name: German Collection of Microorganisms (DSM)
1974Recognition as official depository by the German Patent Office
1976DSM is spun off and run independently at the Institute of Microbiology
1979Transfer to the Society for Biotechnological Research Braunschweig (Director D. Claus)
1981Recognition as international depository for patent purposes according to the Budapest Treaty
1987Establishment of plant cell lines and human and animal cell cultures as new collection areas
1988Renaming to German Collection of Microorganisms and Cell Cultures. DSMZ becomes a GmbH (limited liability company) with the state of Lower Saxony as sole shareholder
1990Plant virus collection added
1996Promotion of the DSMZ as a Blue List institution and subsequently member of the Leibniz Association
2010Establishment of the collection-independent research area Department of Microbial Ecology and Diversity Research
2011Renaming to Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH
2014Establishment of the research department Microbial Genomics as part of DSMZ's participation in the German Center for Infection Research
2016Establishment of the new collection department Bioresources for Bioeconomy and Health Research
2018DSMZ becomes the first registered collection for the implementation of the Nagoya Protocol in the EU
2020Move-in of the Bioresources for Bioeconomy and Health Research Department into the new Center for Drug and Functional Genomics Research. Successful evaluation by the Senate of the Leibniz Association.

Structure

Nearly 200 scientists and technical staff currently work at the DSMZ. [7] It is a company/non-profit organization recognized as a public benefit. [8] In 2018, the Leibniz Institute DSMZ was recognized as the world's first registered collection under Directive (European Union) 511/2014, providing all users with the necessary legal certainty in the handling of their bioresources in accordance with the so-called Nagoya Protocol. [9] [10] The DSMZ is a partner in international organizations such as the European Culture Collections' Organisation (ECCO), the World Federation for Culture Collections (WFCC) and the Global Biodiversity Information Facility (GBIF). [11]

Functions

DSMZ is a global service provider with more than 10,000 customers in over 80 countries and provides microorganisms and cell cultures for university, non-university and industrial research in the life sciences. It also serves as a patent and security depository for biological material (a total of over 11,700 bioresources) in accordance with the guidelines of the Budapest Treaty. [12] It is the only patent depository for bioresources in Germany. [13] The DSMZ only holds bioresources in biosafety level 1 and 2.

In 2012, the freely accessible database BacDive (The Bacterial Diversity Metadatabase) [14] was established, which is maintained and curated by the DSMZ. The database contains information on a wide variety of strains of prokaryotes; in 2016, information on 53,978 strains could be found there, [15] and by 2021, the number had increased to more than 82,000. [16]

Departments

In addition to the research departments Microbial Ecology and Diversity Research [17] and Microbial Genome Research, [18] the eight departments of the DSMZ include the collection departments Microorganisms, [19] Bioresources for Bioeconomy and Health Research, [20] Human and Animal Cell Lines [21] and Plant Viruses [22] as well as the departments Services [23] and Bioinformatics and Databases. [24] The establishment of independent junior research groups (as of 2021: VirusInteract (interactions of plant viruses with their hosts) and Microbial Biotechnology) provides qualification opportunities for young scientists conducting research on selected, current topics.

Related Research Articles

<span class="mw-page-title-main">ATCC (company)</span>

ATCC or the American Type Culture Collection is a nonprofit organization which collects, stores, and distributes standard reference microorganisms, cell lines and other materials for research and development. Established in 1925 to serve as a national center for depositing and distributing microbiological specimens, ATCC has since grown to distribute in over 150 countries. It is now the largest general culture collection in the world.

<i>Venenivibrio stagnispumantis</i> Species of bacterium

Venenivibrio stagnispumantis strain CP.B2 is the first microorganisms isolated from the terrestrial hot spring Champagne Pool in Waiotapu, New Zealand.

Providencia stuartii, is a Gram negative bacillus that is commonly found in soil, water, and sewage. P. stuartii is the most common of the 5 species found in the genus Providencia, with Providencia rettgeri, Providencia alcalifaciens, Providencia rustigianii, P heimbachae. Providencia stuartii can be incubated at 37 °C in nutrient agar or nutrient broth. P. stuartii is the genomic source for the restriction endonuclease, PstI. Some other important information about P. stuartii is that it is motile via flagella, non-sporulating, non-lactose fermenting, catalase positive and oxidase negative. It can also grow in anaerobic conditions and on Simmon’s Citrate Agar.

Afifella is a genus in the phylum Pseudomonadota (Bacteria). Afifella are found in marine and estuarine settings, including microbial mats. They are anaerobes, with one cultured representative capable of photosynthesis.

The Microbial Culture Collection is a microbial culture collection centre in Pune, India. The facility acts as a national depository, supplying authentic microbial cultures and providing related services to research institutions, universities, industries and the scientific community in general. It is funded by the Department of Biotechnology (DBT).

Limnohabitans australis is an aerobic, nonmotile bacterium from the genus Limnohabitans and family Comamonadaceae, which was isolated from a freshwater pond in São Carlos, São Paulo state, Brazil.

Castellaniella caeni is a Gram-negative, oxidase-positive, catalase-negative, facultatively anaerobic, denitrifying, nonmotile bacterium from the genus Castellaniella, isolated from the sludge of the aerobic treatment tanks of a municipal leachate treatment plant in Daejeon in the Republic of Korea.

Thauera humireducens is a gram-negative, non-spore-forming, humus-reducing, rod-shaped, bacterium from the genus of Thauera which was isolated from a microbial fuel cell.

Legionella jamestowniensis is a Gram-negative bacterium from the genus Legionella which was isolated from wet soil in Jamestown, New York.

Bryocella elongata is a bacterium, a type species of genus Bryocella. Cells are Gram-negative, non-motile pink-pigmented rods that multiply by normal cell division and form rosettes. The type strain is SN10(T). B. elongata was first isolated in 2011 from a methanotropic enrichment culture.

Legionella tunisiensis is a Gram-negative bacterium from the genus Legionella isolated from hypersaline lake water from the Lake Sabkha in Tunisia.

Aeromonas enteropelogenes is a Gram-negative, motile bacterium of the genus Aeromonas isolated from human stool in Varanasi, in India.


Bradyrhizobium denitrificans is a bacterium from the genus Bradyrhizobium which was isolated from surface lake water in Germany.

Streptomyces mutabilis is a bacterium species from the genus of Streptomyces which has been isolated from soil. Streptomyces mutabilis produces the antibiotic mutalomycin. Streptomyces mutabilis UAE1 has been found to promote plant growth in gray mangroves under greenhouse conditions by producing polyamines putrescine (Put), spermidine (Spd), and spermine (Spm).

<span class="mw-page-title-main">BacDive</span> Online database for bacteria

BacDive is a bacterial metadatabase that provides strain-linked information about bacterial and archaeal biodiversity.

Eggerthia catenaformis is an anaerobic, Gram-positive, non-spore-forming rod-shaped bacterium. It is an uncommon cause of infection in humans and is known to be associated with dental abscess.

Muribaculum intestinale is a strictly anaerobic bacterium from the genus of Muribaculum which has been isolated from the caecal content of a mouse in Zurich in Switzerland.

Azorhizophilus paspali is a bacterium from the genus of Azorhizophilus which has been isolated from rhizosphere soil from the plant Paspalum notatum in Brazil.

The 'German Network for Bioinformatics Infrastructure – de.NBI' is a national, academic and non-profit infrastructure initiated by the Federal Ministry of Education and Research funding 2015-2021. The network provides bioinformatics services to users in life sciences research and biomedicine in Germany and Europe. The partners organize training events, courses and summer schools on tools, standards and compute services provided by de.NBI to assist researchers to more effectively exploit their data. From 2022, the network will be integrated into Forschungszentrum Jülich.

Phaeobacter porticola is a bacterium from the genus of Phaeobacter which has been isolated from barnacle from Neuharlingersiel in Germany.) Phaeobacter porticola produces antibiotics.

References

  1. "German Collection of Microorganisms and Cell Cultures GMBH: Mission".
  2. "German Collection of Microorganisms and Cell Cultures GMBH: Catalogue".
  3. https://www.dsmz.de/
  4. "German Collection of Microorganisms and Cell Cultures GMBH: Management".
  5. "German Collection of Microorganisms and Cell Cultures GMBH: Management".
  6. "German Collection of Microorganisms and Cell Cultures GMBH: Management".
  7. "Bakterien für ein besseres und gesünderes Leben".
  8. "German Collection of Microorganisms and Cell Cultures GMBH: Mission".
  9. "German Collection of Microorganisms and Cell Cultures GMBH: Collection".
  10. "German Collection of Microorganisms and Cell Cultures GMBH: Nagoya Protocol".
  11. "German Collection of Microorganisms and Cell Cultures GMBH: Network".
  12. "Guide to the Deposit of Microorganisms under the Budapest Treaty".
  13. "German Collection of Microorganisms and Cell Cultures GMBH: Patent Deposit".
  14. "German Collection of Microorganisms and Cell Cultures GMBH: BacDive".
  15. Söhngen, Carola; Podstawka, Adam; Bunk, Boyke; Gleim, Dorothea; Vetcininova, Anna; Reimer, Lorenz Christian; Ebeling, Christian; Pendarovski, Cezar; Overmann, Jörg (4 January 2016). "Bac Dive – the Bacterial Diversity Metadatabase in 2016". Nucleic Acids Research. 44 (D1): D581–D585. doi:10.1093/nar/gkv983. PMC   4702946 . PMID   26424852.
  16. https://bacdive.dsmz.de/
  17. "German Collection of Microorganisms and Cell Cultures GMBH: Microbial Ecology and Diversity Research".
  18. "German Collection of Microorganisms and Cell Cultures GMBH: Microbial Genome Research".
  19. "German Collection of Microorganisms and Cell Cultures GMBH: Microorganisms".
  20. "German Collection of Microorganisms and Cell Cultures GMBH: Bioresources for Bioeconomy and Health Research".
  21. "German Collection of Microorganisms and Cell Cultures GMBH: Human and Animal Cell Lines".
  22. "German Collection of Microorganisms and Cell Cultures GMBH: Plant Viruses".
  23. "German Collection of Microorganisms and Cell Cultures GMBH: Analytics".
  24. "German Collection of Microorganisms and Cell Cultures GMBH: Bioinformatics".