Douglas L. Mann

Last updated
Douglas L.Mann
Alma mater
Scientific career
Institutions Washington University School of Medicine
Website

Douglas L. Mann is an American physician. He is currently the Ada L. Steininger Professor of Cardiology [1] and professor of medicine, cell biology and physiology at Washington University School of Medicine in St. Louis. [2]

Contents

Education

Mann received his undergraduate training at Lafayette College, in Easton, Pennsylvania and his Medical degree from Temple University School of Medicine, Philadelphia, Pennsylvania.  After finishing his residency in medicine at Temple University Hospital, he completed his cardiology fellowship at the University of California, San Diego.

He was a clinical and research fellow at the Massachusetts General Hospital, Boston, Massachusetts and a research fellow in cardiology at Temple University Hospital. Prior to joining the faculty at Washington University School of Medicine in St. Louis, he was on staff at the Medical University of South Carolina and Baylor College of Medicine. He is on the faculty at Washington University School of Medicine in St. Louis, where he was the chief of the cardiovascular division from 2009 to 2019. [3]

Research and career

Mann's research on the cellular and molecular basis for heart failure uncovered an important role for innate immunity in disease progression in the failing heart. [4] His work in the field of cardio-immunology demonstrated that the heart expresses pro-inflammatory cytokines following cardiac injury and that the expression of pro-inflammatory cytokines mimics the heart failure phenotype in experimental models. [5] [6] Clinically, Mann has translated his basic research observations into phase I and phase III trials that have targeted inflammatory pathways in heart failure. [7]

Awards and honors

Mann is a member of the American Society for Clinical Investigation, the American Association of Physicians, the Heart Failure Society of America, the American Clinical and Climatological Association and is a fellow of the American College of Cardiology. His is the editor-in-chief of JACC: Basic to Translational Science , and an editor for Braunwald’s Heart Disease. [8] [9] [10]

He has received numerous awards including the Michael E. DeBakey award for excellence in research, the Distinguished Mentor Award, American College of Cardiology, and the 2019 Lifetime achievement award from the Heart Failure Society of America and the 2020 lifetime achievement award from the European Heart Failure Association. [11] [12] He is the past president of the Heart Failure Society and the Medical Alumnus of the Year award from Temple University School of Medicine. He was recognized by Forbes magazine as one of the top 27 cardiologists in the United States. [13] [14]

Related Research Articles

<span class="mw-page-title-main">Myocarditis</span> Inflammation of the heart muscle

Myocarditis, also known as inflammatory cardiomyopathy, is an acquired cardiomyopathy due to inflammation of the heart muscle. Symptoms can include shortness of breath, chest pain, decreased ability to exercise, and an irregular heartbeat. The duration of problems can vary from hours to months. Complications may include heart failure due to dilated cardiomyopathy or cardiac arrest.

<span class="mw-page-title-main">Paul Ridker</span> American epidemiologist and academic

Paul M. Ridker is a cardiovascular epidemiologist and biomedical researcher. He is currently the Eugene Braunwald Professor of Medicine at Harvard University and Brigham and Women's Hospital, where he directs the Center for Cardiovascular Disease Prevention. Ridker also holds an appointment as Professor in the Department of Epidemiology at the Harvard T.H. Chan School of Public Health.

Avijit Lahiri is a researcher in cardiology in the UK.

The Canadian Cardiovascular Society (CCS) is the national voice for cardiovascular physicians and scientists in Canada. The CCS is a membership organization that represents more than 1,800 professionals in the cardiovascular field. Its mission is to promote cardiovascular health and care through knowledge translation, professional development and leadership in health policy.

<span class="mw-page-title-main">Libin Cardiovascular Institute</span>

The Libin Cardiovascular Institute is an entity of Alberta Health Services and the University of Calgary. It connects all cardiovascular research, education and patient care in Southern Alberta, serving a population of about two million. Its more than 1,500 members include physicians, clinicians and other health professionals, researchers and trainees.

<span class="mw-page-title-main">Valentín Fuster</span> Spanish cardiologist

Valentín Fuster Carulla, 1st Marquess of Fuster is a Spanish cardiologist and aristocrat.

Annapoorna Kini is an American cardiologist. She is Professor of Cardiology and Interventional Director of Structural Heart Program at Mount Sinai School of Medicine in New York City.

<i>Journal of the American College of Cardiology</i> Academic journal

The Journal of the American College of Cardiology is a peer-reviewed medical journal covering all aspects of cardiovascular disease, including original clinical studies, translational investigations with clear clinical relevance, state-of-the-art papers, review articles, and editorials interpreting and commenting on the research presented, published by the American College of Cardiology.

Jonathan L. Halperin is an American cardiologist and the author of Bypass (ISBN 0-89586-509-2), among the most comprehensive works on the subject of coronary artery bypass surgery. In addition, he is the Robert and Harriet Heilbrunn Professor of Medicine at The Mount Sinai School of Medicine as well as Director of Clinical Cardiology in the Zena and Michael A. Wierner Cardiovascular Institute at The Mount Sinai Medical Center, both in New York City. Halperin was the principal cardiologist responsible for both the design and execution of the multi-center Stroke Prevention in Atrial Fibrillation (SPAF) clinical trials, funded by the National Institutes of Health, which helped develop antithrombotic strategies to prevent stroke, and he subsequently directed the SPORTIF clinical trials, which evaluated the first oral direct thrombin inhibitor for prevention of stroke in patients with atrial fibrillation.

John S. Rumsfeld is an American cardiologist. He is the Chief Innovation Officer for the American College of Cardiology, and Professor of Medicine at the University of Colorado School of Medicine. He was previously the National Director of Cardiology for the U.S. Veterans Health Administration. Rumsfeld was named as Chief Innovation Officer for American College of Cardiology in 2015.

<span class="mw-page-title-main">Heart failure with preserved ejection fraction</span> Medical condition

Heart failure with preserved ejection fraction (HFpEF) is a form of heart failure in which the ejection fraction – the percentage of the volume of blood ejected from the left ventricle with each heartbeat divided by the volume of blood when the left ventricle is maximally filled – is normal, defined as greater than 50%; this may be measured by echocardiography or cardiac catheterization. Approximately half of people with heart failure have preserved ejection fraction, while the other half have a reduction in ejection fraction, called heart failure with reduced ejection fraction (HFrEF).

Clyde Warren Yancy is an American cardiologist and the Magerstadt Professor at Northwestern University Feinberg School of Medicine. He has previously served as the Past President of the American Heart Association. His research considers heart failure, heart transplantation and ways to prevent heart failure. He is Vice Dean of Diversity and Inclusion.

Milton Packer is an American cardiologist who is known for his clinical research concerning heart failure.

<span class="mw-page-title-main">Béla Merkely</span> Hungarian cardiologist (born 1966)

Dr. Béla Merkely is a Hungarian interventional cardiologist and sports cardiologist, a university professor, director of Semmelweis University's Heart and Vascular Centre and the current rector of Semmelweis University since 1 July 2018.

Ayodele Olajide Falase is a Nigerian cardiologist and academic. He is a former vice chancellor of the University of Ibadan. He served as a WHO Expert committee member on cardiopathies and on a WHO expert panel on cardiovascular disease. Professor Ayodele Falase got the Honorary fellowship award at the University of Ibadan 71st founder’s day held in 2019.

Dr. Robert S. Rosenson is a Professor of Medicine and also lending his services as the Director of cardio metabolic disorders at the Icahn School of Medicine at Mount Sinai.

<span class="mw-page-title-main">Richard Gorlin</span> American cardiologist

Richard Gorlin was an American cardiologist known for his contributions to the fields of valvular heart disease, coronary artery disease and cardiac catheterization, digitalis and vasodilators in congestive heart failure, and thrombolysis in myocardial infarctions. Along with his father, developed the Gorlin formula used to calculate valve areas in aortic valve stenosis and mitral valve stenosis.

Partho P. Sengupta is an Indian-American cardiologist. He is the Henry Rutgers Professor of Cardiology and Chief of the Division of Cardiovascular Disease & Hypertension at the Robert Wood Johnson Medical School (RWJMS) and the Chief of Cardiology, Robert Wood Johnson University Hospital (RWJUH) since July 1, 2021. Between 2019 and 2021, Dr. Sengupta was the Abnash C. Jain Chair & Professor of Cardiology at West Virginia University School of Medicine and the Chief of Division of Cardiology, Chair of Cardiovascular Innovation and Director of Cardiac Imaging at West Virginia University Heart and Vascular Institute.

Michelle Asha Albert is an American physician who is the Walter A. Haas Lucie-Stern Endowed Chair in Cardiology and professor of medicine at the University of California, San Francisco. Albert is director of the UCSF Center for the Study of Adversity and Cardiovascular Disease. She is president of the American Heart Association. She served as the president of the Association of Black Cardiologists in 2020–2022 and as president of the Association of University Cardiologists (2021–2022). Albert is an elected member of the National Academy of Medicine, the American Society of Clinical Investigators and the Association of American Physicians.

<span class="mw-page-title-main">Roxana Mehran</span> Cardiologist

Roxana Mehran is an Iranian-American cardiologist and Mount Sinai Endowed Professor of Medicine at the Icahn School of Medicine at Mount Sinai. She is known for her work in interventional cardiology.

References

  1. ↑ Strait, Julia Evangelou (21 February 2022). "Mann honored by American College of Cardiology". Washington University School of Medicine .
  2. ↑ "Washington People: Douglas L. Mann | The Source | Washington University in St. Louis". The Source. 2011-08-26. Retrieved 2020-05-26.
  3. ↑ "Douglas L. Mann, MD". Cardiovascular Division. Retrieved 2020-05-26.
  4. ↑ Today, Cardiology; November 2010. "Douglas L. Mann, MD, leader, scholar and innovator in HF therapeutics". www.healio.com. Retrieved 2020-05-26.{{cite web}}: CS1 maint: numeric names: authors list (link)
  5. ↑ Kapadia, S.; Lee, J.; Torre-Amione, G.; Birdsall, H. H.; Ma, T. S.; Mann, D. L. (1995-08-01). "Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration". The Journal of Clinical Investigation. 96 (2): 1042–1052. doi:10.1172/JCI118090. ISSN   0021-9738. PMC   286384 . PMID   7635940.
  6. ↑ Torre-Amione, Guillermo; Kapadia, Samir; Benedict, Claude; Oral, Hakan; Young, James B.; Mann, Douglas L. (1996-04-01). "Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD)". Journal of the American College of Cardiology. 27 (5): 1201–1206. doi: 10.1016/0735-1097(95)00589-7 . ISSN   0735-1097. PMID   8609343.
  7. ↑ Dl, Mann; Jj, McMurray; M, Packer; K, Swedberg; Js, Borer; Ws, Colucci; J, Djian; H, Drexler; A, Feldman (2004-04-06). "Targeted Anticytokine Therapy in Patients With Chronic Heart Failure: Results of the Randomized Etanercept Worldwide Evaluation (RENEWAL)". Circulation. 109 (13): 1594–602. doi: 10.1161/01.CIR.0000124490.27666.B2 . PMID   15023878. S2CID   2158143.
  8. ↑ "Medicine Grand Rounds, Visiting Professor in Cardiology Asks, 'Is It Time to Rethink Heart Failure Classification?' | Department of Medicine". deptmedicine.arizona.edu. Retrieved 2019-05-17.
  9. ↑ "Douglas L. Mann Named Editor-in-Chief of New JACC: Basic Translational Research Journal". American College of Cardiology. Retrieved May 13, 2020.
  10. ↑ "Douglas Mann". PracticeUpdate. Retrieved 2020-05-26.
  11. ↑ "bcm.edu". Archived from the original on 2019-07-12.
  12. ↑ "Lifetime Achievement Award Spotlight: Douglas L. Mann, MD, FHFSA | HFSA". hfsa.org. Retrieved 2020-05-26.
  13. ↑ "Douglas L. Mann, MD". Cardiovascular Division. Retrieved 2019-05-17.
  14. ↑ Herper, Matthew. "27 Top Cardiologists, Picked By Big Data". Forbes. Retrieved 2020-05-26.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.