Susan Lee Lindquist,ForMemRS was an American professor of biology at MIT specializing in molecular biology,particularly the protein folding problem within a family of molecules known as heat-shock proteins,and prions. Lindquist was a member and former director of the Whitehead Institute and was awarded the National Medal of Science in 2010.
George Wells Beadle was an American geneticist. In 1958 he shared one-half of the Nobel Prize in Physiology or Medicine with Edward Tatum for their discovery of the role of genes in regulating biochemical events within cells. He also served as the 7th President of the University of Chicago.
Sir Peter James Donnelly is an Australian-British mathematician and Professor of Statistical Science at the University of Oxford,and the CEO of Genomics PLC. He is a specialist in applied probability and has made contributions to coalescent theory. His research group at Oxford has an international reputation for the development of statistical methodology to analyze genetic data.
The Feinberg School of Medicine is the medical school of Northwestern University and is located in the Streeterville neighborhood of Chicago,Illinois. Founded in 1859,Feinberg offers a full-time Doctor of Medicine degree program,multiple dual degree programs,graduate medical education,and continuing medical education.
Mary-Claire King is an American geneticist. She was the first to show that breast cancer can be inherited due to mutations in the gene she called BRCA1. She studies human genetics and is particularly interested in genetic heterogeneity and complex traits. She studies the interaction of genetics and environmental influences and their effects on human conditions such as breast and ovarian cancer,inherited deafness,schizophrenia,HIV,systemic lupus erythematosus and rheumatoid arthritis. She has been the American Cancer Society Professor of the Department of Genome Sciences and of Medical Genetics in the Department of Medicine at the University of Washington since 1995.
Elaine V. Fuchs is an American cell biologist known for her work on the biology and molecular mechanisms of mammalian skin and skin diseases,who helped lead the modernization of dermatology. Fuchs pioneered reverse genetics approaches,which assess protein function first and then assess its role in development and disease. In particular,Fuchs researches skin stem cells and their production of hair and skin. She is an investigator at the Howard Hughes Medical Institute and the Rebecca C. Lancefield Professor of Mammalian Cell Biology and Development at The Rockefeller University.
Elizabeth Fondal Neufeld is a French-American geneticist whose research has focused on the genetic basis of metabolic disease in humans.
Huda Yahya Zoghbi,born Huda El-Hibri,is a Lebanese-born American geneticist,and a professor at the Departments of Molecular and Human Genetics,Neuroscience and Neurology at the Baylor College of Medicine. She is the director of the Jan and Dan Duncan Neurological Research Institute. She became the editor of the Annual Review of Neuroscience as of 2018.
Rajesh Vasantlal Thakker is May Professor of Medicine in the Nuffield Department of Clinical Medicine at the University of Oxford and a fellow of Somerville College,Oxford. Thakker is also a Consultant physician at the Churchill Hospital and the John Radcliffe Hospital,Principal investigator (PI) at the Oxford Centre for Diabetes,Endocrinology and Metabolism (OCDEM) and was Chairman of the NIHR/MRC Efficacy and Mechanism Evaluation (EME) Board until Spring 2016.
Stuart Holland Orkin is an American physician,stem cell biologist and researcher in pediatric hematology-oncology. He is the David G. Nathan Distinguished Professor of Pediatrics at Harvard Medical School. Orkin's research has focused on the genetic basis of blood disorders. He is a member of the National Academy of Sciences and the Institute of Medicine,and an Investigator of the Howard Hughes Medical Institute.
A human disease modifier gene is a modifier gene that alters expression of a human gene at another locus that in turn causes a genetic disease. Whereas medical genetics has tended to distinguish between monogenic traits,governed by simple,Mendelian inheritance,and quantitative traits,with cumulative,multifactorial causes,increasing evidence suggests that human diseases exist on a continuous spectrum between the two.
Teresa Kaye Woodruff is an American medical researcher in human reproduction and oncology,with a focus on ovarian biology,endocrinology,and women's health. She joined Michigan State University as the Provost and Executive Vice President for Academic Affairs in August 2020. Woodruff served as the interim President of Michigan State University from November 4,2022 to March 4,2024,following the resignation of Samuel L. Stanley. She was previously the Thomas J. Watkins Memorial Professor and Vice Chair for Research and Chief of the Division of Reproductive Science in Medicine in the Department of Obstetrics and Gynecology at the Feinberg School of Medicine at Northwestern University in Chicago,Illinois.
Charis Eng is a Singapore-born physician-scientist and geneticist at the Cleveland Clinic,notable for identifying the PTEN gene. She is the Chairwoman and founding Director of the Genomic Medicine Institute of the Cleveland Clinic,founding Director and attending clinical cancer geneticist of the institute’s clinical component,the Center for Personalized Genetic Healthcare,and Professor and Vice Chairwoman of the Department of Genetics and Genome Sciences at Case Western Reserve University School of Medicine.
Thomas Wesley McDade is an American biological anthropologist. He is a Fellow of the American Association for the Advancement of Science,the National Academy of Sciences,and the American Academy of Arts and Sciences.
Johanna Rommens is a Canadian geneticist who was on the research team which identified and cloned the CFTR gene,which when mutated,is responsible for causing cystic fibrosis (CF). She later discovered the gene responsible for Shwachman-Diamond syndrome,a rare genetic disorder that causes pancreatic and hematologic problems. She is a Senior Scientist Emeritus at SickKids Research Institute and a professor in the Department of Molecular Genetics at the University of Toronto.
Melina R. Kibbe is an American clinician and researcher in the field of vascular surgery. She currently serves as Dean of the University of Virginia School of Medicine. She previously held the Colin G. Thomas Jr. Distinguished Professorship and Chair of the Department of Surgery at UNC School of Medicine.
Katalin Susztak (Suszták) is a Hungarian American scientist and nephrologist at the Perelman School of Medicine at the University of Pennsylvania. She is a professor of medicine and genetics,and currently the codirector of the Complications Unit at the Institute for Diabetes,Obesity and Metabolism. Her laboratory made major contributions to the current understanding of kidney disease development. She is also the founder of the Transformative Research In DiabEtic NephropaThy (TRIDENT),a collaborative network of physicians and basic scientists,to find cures for diabetic kidney disease.
Wylie Burke is a Professor Emerita and former Chair of the Department of Bioethics and Humanities at the University of Washington and a founding co-director of the Northwest-Alaska Pharmacogenomics Research Network,which partners with underserved populations in the Pacific Northwest and Alaska.
Dimitri Krainc is a Slovenian-born American physician-scientist who is the Aaron Montgomery Ward Professor and Chairman of the Ken &Ruth Davee Department of Neurology and Director of the Feinberg Neuroscience Institute and the Simpson Querrey Center for Neurogenetics at Northwestern University Feinberg School of Medicine. After completing his medical training at the University of Zagreb,Krainc spent more than two decades at the Massachusetts General Hospital and Harvard Medical School,where he completed his research and clinical training and served on faculty until relocating to Northwestern University in 2013. He has dedicated his scientific career to studying molecular pathways in the pathogenesis of neurodegeneration. Informed by genetic causes of disease,his work has uncovered key mechanisms across different neurodegenerative disorders that have led to pioneering design and development of targeted therapies. He has received numerous awards and recognitions for his work,including the Javits Neuroscience Investigator Award and the Outstanding Investigator award from NIH,and was elected to the Association of American Physicians,the National Academy of Medicine,and the National Academy of Inventors. He is the principal founding scientist of two biotech companies and serves as Venture Partner at OrbiMed. Krainc is President-elect of the American Neurological Association.
Anne Goriely is a British geneticist who is a professor of human genetics at the University of Oxford. Her research investigates the molecular mechanisms that underpin genetic variation,particularly mutations in the male germline.
