Endoluminal capsule monitoring

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Endoluminal capsule monitoring

Endoluminal capsule monitoring is a non-invasive medical diagnostic procedure which uses a miniaturized wireless radio transmitter embedded into an ingestible water-tight capsule. [1] [2] The patient ingests the capsule and while it transits through the gastrointestinal system, it sends signals to the outside, which are captured by a radio receiver, processed, displayed and stored in a computer.

According to the type or type(s) of biomedical sensors which are built into the capsule, several physiological parameters can be measured and transmitted by the capsule:

A wireless motility capsule (WMC) can measure gastric emptying time to diagnose gastroparesis or gastric dumping syndrome, and it can also measure transit time in the small intestine and colon. The WMC uses pH to detect passage through the pyloric sphincter and through the ileocecal valve, and it uses a temperature sensor to detect elimination from the body. [3]

Modern capsules, called video pills or endoscopic capsules can also transmit endoscopic images from a miniature video camera.

The system is normally used for research purposes or for diagnosing long term changes in gastrointestinal physiological parameters. In some cases, the capsule is recovered in the feces, sterilized, and can be used again. In other cases, the capsule is discarded with the feces, serving as a disposable medical device. [3]

Related Research Articles

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Gastroenterology is the branch of medicine focused on the digestive system and its disorders. The digestive system consists of the gastrointestinal tract, sometimes referred to as the GI tract, which includes the esophagus, stomach, small intestine and large intestine as well as the accessory organs of digestion which include the pancreas, gallbladder, and liver. The digestive system functions to move material through the GI tract via peristalsis, break down that material via digestion, absorb nutrients for use throughout the body, and remove waste from the body via defecation. Physicians who specialize in the medical specialty of gastroenterology are called gastroenterologists or sometimes GI doctors. Some of the most common conditions managed by gastroenterologists include gastroesophageal reflux disease, gastrointestinal bleeding, irritable bowel syndrome, inflammatory bowel disease (IBD) which includes Crohn's disease and ulcerative colitis, peptic ulcer disease, gallbladder and biliary tract disease, hepatitis, pancreatitis, colitis, colon polyps and cancer, nutritional problems, and many more.

<span class="mw-page-title-main">Large intestine</span> Last part of the digestive system in vertebrates

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<span class="mw-page-title-main">Gastrointestinal tract</span> Organ system within humans and other animals

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<span class="mw-page-title-main">Endoscope</span> Instrument to visually examine the interior of a hollow space

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<span class="mw-page-title-main">Fecal occult blood</span> Medical condition

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<span class="mw-page-title-main">Malabsorption</span> Medical condition

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Colic in horses is defined as abdominal pain, but it is a clinical symptom rather than a diagnosis. The term colic can encompass all forms of gastrointestinal conditions which cause pain as well as other causes of abdominal pain not involving the gastrointestinal tract. What makes it tricky is that different causes can manifest with similar signs of distress in the animal. Recognizing and understanding these signs is pivotal, as timely action can spell the difference between a brief moment of discomfort and a life-threatening situation. The most common forms of colic are gastrointestinal in nature and are most often related to colonic disturbance. There are a variety of different causes of colic, some of which can prove fatal without surgical intervention. Colic surgery is usually an expensive procedure as it is major abdominal surgery, often with intensive aftercare. Among domesticated horses, colic is the leading cause of premature death. The incidence of colic in the general horse population has been estimated between 4 and 10 percent over the course of the average lifespan. Clinical signs of colic generally require treatment by a veterinarian. The conditions that cause colic can become life-threatening in a short period of time.

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<span class="mw-page-title-main">Capsule endoscopy</span> Medical imaging procedure

Capsule endoscopy is a medical procedure used to record internal images of the gastrointestinal tract for use in disease diagnosis. Newer developments are also able to take biopsies and release medication at specific locations of the entire gastrointestinal tract. Unlike the more widely used endoscope, capsule endoscopy provides the ability to see the middle portion of the small intestine. It can be applied to the detection of various gastrointestinal cancers, digestive diseases, ulcers, unexplained bleedings, and general abdominal pains. After a patient swallows the capsule, it passes along the gastrointestinal tract, taking a number of images per second which are transmitted wirelessly to an array of receivers connected to a portable recording device carried by the patient. General advantages of capsule endoscopy over standard endoscopy include the minimally invasive procedure setup, ability to visualize more of the gastrointestinal tract, and lower cost of the procedure.

<span class="mw-page-title-main">Gastroparesis</span> Medical condition

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<span class="mw-page-title-main">Given Imaging</span>

Given Imaging is an Israeli medical technology company that manufactures and markets diagnostic products for the visualization and detection of disorders of the gastrointestinal tract. Until March 2014, it was dual-listed on both the NASDAQ and the Tel Aviv Stock Exchange, where it was a component of the TA-100 Index and the TA BlueTech Index. In March 2014 it was acquired by Covidien and became a private company. In 2015 Covidien was purchased by Medtronic.

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Esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment. It can also be used in diagnosing laryngopharyngeal reflux.

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Chromoendoscopy is a medical procedure wherein dyes are instilled into the gastrointestinal tract at the time of visualization with fibre-optic endoscopy. The purposes of chromoendoscopy is chiefly enhance the characterization of tissues, although dyes may be used for other functional purposes. The detail achieved with chromoendoscopy can often allow for identification of the tissue type or pathology based upon the pattern uncovered.

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A digital pill is a pharmaceutical dosage form that contains an ingestible sensor inside of a pill. The sensor begins transmitting medical data after it is consumed. The technology that makes up the pill, as well as the data transmitted by the pill's sensor, are considered to be part of digital medicine. The purpose of the sensor is to determine whether the person is taking their medication or not. There are privacy concerns with respect to who receives the data and what is done with it. Such privacy concerns, along with uncertain economic benefits, have made the broad introduction of digital pills in the healthcare practice challenging, despite accumulating body of clinical evidence indicating their efficacy and safety.

References

  1. Mostafanezhad, Isar; Boric-Lubecke, Olga; Lin, Jenshan (2017-12-07). Medical and Biological Microwave Sensors and Systems. Cambridge University Press. p. 4. ISBN   978-1-316-98260-0.
  2. Nilmini, Wickramasinghe; Eliezer, Geisler (2008-06-30). Encyclopedia of Healthcare Information Systems. IGI Global. p. 889. ISBN   978-1-59904-890-1.
  3. 1 2 "SmartPill Information for Healthcare Professionals by MedTronic".