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Johann Deisenhofer is a German biochemist who, along with Hartmut Michel and Robert Huber, received the Nobel Prize for Chemistry in 1988 for their determination of the first crystal structure of an integral membrane protein, a membrane-bound complex of proteins and co-factors that is essential to photosynthesis.
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Magnetoreception is a sense which allows an organism to detect a magnetic field to perceive direction, altitude or location. This sensory modality is used by a range of animals for orientation and navigation, and as a method for animals to develop regional maps. In navigation, magnetoreception deals with the detection of the Earth's magnetic field.
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The cuticulosome is a spherical, iron-rich structure located in the cuticular plate of auditory and vestibular hair cells in birds. Cuticulosomes are 300-600 nm in diameter and are composed of ferritin-like granules that in some cases are structured in paracrystalline arrays. Due to its specific location in sensory hair cells of the inner ear and its iron-rich composition it was proposed to be involved in the magnetic sense of birds. However, physical simulations and calculations showed that it lacks sufficient magnetic susceptibility to act as a torque based magnetoreceptor. An alternative hypothesis suggests that the cuticulosome might work as an intracellular electromagnetic oscillator to detect magnetic fields.
David Anthony Keays is an Australian neuroscientist who studies magnetoreception and neurodevelopment. He is currently a group leader at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria, Chair of Organismal and Developmental Neurobiology at the Ludwig Maximilians University (LMU) in Munich, and Honorary Associate Professor at the University of Melbourne.
Ardem Patapoutian is an American molecular biologist, neuroscientist, and Nobel Prize laureate. He is known for his work in characterizing the PIEZO1, PIEZO2, and TRPM8 receptors that detect pressure, menthol, and temperature. Patapoutian is a neuroscience professor and Howard Hughes Medical Institute investigator at Scripps Research in La Jolla, California. In 2021, he won the Nobel Prize in Physiology or Medicine jointly with David Julius.
References
- ↑ Malkemper, E. Pascal; Eder, Stephan H. K.; Begall, Sabine; Phillips, John B.; Winklhofer, Michael; Hart, Vlastimil; Burda, Hynek (May 2015). "Magnetoreception in the wood mouse (Apodemus sylvaticus): influence of weak frequency-modulated radio frequency fields". Scientific Reports. 5 (1): 9917. Bibcode:2015NatSR...4E9917M. doi:10.1038/srep09917. ISSN 2045-2322. PMC 4413948 . PMID 25923312.
- ↑ "The Ig Nobel Prize Winners". Improbable Research. 2006-08-01. Retrieved 2020-04-14.
- ↑ Malkemper, E. Pascal; Kagerbauer, Daniel; Ushakova, Lyubov; Nimpf, Simon; Pichler, Paul; Treiber, Christoph D.; de Jonge, Martin; Shaw, Jeremy; Keays, David A. (January 2019). "No evidence for a magnetite-based magnetoreceptor in the lagena of pigeons". Current Biology. 29 (1): R14–R15. doi: 10.1016/j.cub.2018.11.032 . PMID 30620907.
