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Proton computed tomography (pCT), or proton CT, is an imaging modality first proposed by Cormack in 1963 and initial experiment explorations identified several advantages over conventional X-ray CT (xCT). However, particle interactions such as multiple Coulomb scattering (MCS) and (in)elastic nuclear scattering events deflect the proton trajectory, resulting in nonlinear paths which can only be approximated via statistical assumptions, leading to lower spatial resolution than X-ray tomography. Further experiments were largely abandoned until the advent of proton radiation therapy in the 1990s which renewed interest in the topic due to the potential benefits of imaging and treating patients with the same particle.
Hrvoje Brkić, Croatian biophysicist. He was born in Vinkovci, where he attended elementary school and Gymnasium Matija Antun Reljković. In 2007. he finished Physics department of J. J. Strossmayer University of Osijek, and approached to the PhD in Faculty of natural sciences in Zagreb. PhD thesis named Computational studies of Iron dependent dioxygenases, under mentor prof. Sanja Tomić, was defended in 2014th. Till now has co-authored approximately 30 internationally reviewed scientific papers.
References
- ↑ The official FLUKA site: FLUKA home FLUKA Team
- ↑ Battistoni, Giuseppe; Boehlen, Till; Cerutti, Francesco; Chin, Pik Wai; Esposito, Luigi Salvatore; Fassò, Alberto; Ferrari, Alfredo; Lechner, Anton; Empl, Anton; Mairani, Andrea; Mereghetti, Alessio; Ortega, Pablo Garcia; Ranft, Johannes; Roesler, Stefan; Sala, Paola R.; Vlachoudis, Vasilis; Smirnov, George (2015). "Overview of the FLUKA code". Annals of Nuclear Energy. 82: 10–18. doi: 10.1016/j.anucene.2014.11.007 . ISSN 0306-4549.
- ↑ Fassò, A.; Ferrari, A.; Ranft, Johannes; Sala, Paola R. (2005). FLUKA: a multi-particle transport code, CERN 2005-10 (2005), INFN/TC_05/11, SLAC-R-773. CERN Yellow Reports: Monographs. doi:10.5170/CERN-2005-010. ISBN 9789290832607.
- ↑ Battistoni, G.; Cerutti, F.; Fassò, A.; Ferrari, A.; Muraro, S.; Ranft, J.; Roesler, S.; Sala, P. R. (2007). "The FLUKA code: description and benchmarking". AIP Conference Proceedings. Vol. 896. pp. 31–49. doi:10.1063/1.2720455. ISSN 0094-243X.
{{cite book}}:|journal=ignored (help) - ↑ Battistoni, Giuseppe; Margiotta, Annarita; Muraro, Silvia; Sioli, Maximiliano (2011). "FLUKA as a new high energy cosmic ray generator". Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 626–627: S191–S192. arXiv: 1002.4655 . Bibcode:2011NIMPA.626S.191B. doi:10.1016/j.nima.2010.05.019. ISSN 0168-9002. S2CID 119208962.
- ↑ Battistoni, G.; Ferrari, A.; Montaruli, T.; Sala, P.R. (2002). "Comparison of the FLUKA calculations with CAPRICE94 data on muons in atmosphere". Astroparticle Physics. 17 (4): 477–488. arXiv: hep-ph/0107241 . Bibcode:2002APh....17..477B. doi:10.1016/S0927-6505(01)00176-1. ISSN 0927-6505. S2CID 204927907.
- ↑ Roesler, S.; Heinrich, W.; Schraube, H. (2002). "Monte Carlo Calculation of the Radiation Field at Aircraft Altitudes" (PDF). Radiation Protection Dosimetry. 98 (4): 367–388. doi:10.1093/oxfordjournals.rpd.a006728. ISSN 0144-8420. PMID 12120665.
- ↑ Battistoni, Giuseppe; Bauer, Julia; Boehlen, Till T.; Cerutti, Francesco; Chin, Mary P. W.; Dos Santos Augusto, Ricardo; Ferrari, Alfredo; Ortega, Pablo G.; Kozłowska, Wioletta; Magro, Giuseppe; Mairani, Andrea; Parodi, Katia; Sala, Paola R.; Schoofs, Philippe; Tessonnier, Thomas; Vlachoudis, Vasilis (2016). "The FLUKA Code: An Accurate Simulation Tool for Particle Therapy". Frontiers in Oncology. 6: 116. doi: 10.3389/fonc.2016.00116 . ISSN 2234-943X. PMC 4863153 . PMID 27242956.
- ↑ Zhang, Qinghui; Lee, Chaeyeong; Lee, Sangmin; Lee, Seung-Jae; Song, Hankyeol; Kim, Dae-Hyun; Cho, Sungkoo; Jo, Kwanghyun; Han, Youngyih; Chung, Yong Hyun; Kim, Jin Sung (2017). "Monte Carlo simulation of secondary neutron dose for scanning proton therapy using FLUKA". PLOS ONE. 12 (10): e0186544. Bibcode:2017PLoSO..1286544L. doi: 10.1371/journal.pone.0186544 . ISSN 1932-6203. PMC 5646843 . PMID 29045491.
- ↑ "A Monte Carlo code for ion beam therapy". CERN Document Server. Retrieved 22 October 2023.
- ↑ Battistoni, Giuseppe; Broggi, Francesco; Brugger, Markus; Campanella, Mauro; Carboni, Massimo; Empl, Anton; Fassò, Alberto; Gadioli, Ettore; Cerutti, Francesco; Ferrari, Alfredo; Ferrari, Anna; Garzelli, Maria Vittoria; Lantz, Mattias; Mairani, Andrea; Margiotta, M. (1 October 2011). "The Application of the Monte Carlo Code FLUKA in Radiation Protection Studies for the Large Hadron Collider" (PDF). Progress in Nuclear Science and Technology. 2 (0): 358–364. doi:10.15669/pnst.2.358. ISSN 2185-4823.
- ↑ Jeffrey R. Davis, Robert Johnson, Jan Stepanek - Fundamentals of Aerospace Medicine (2008) - Page 228-230 (Google Books Link 2010)
- 1 2 Randeniya, S. D.; Taddei, P. J.; Newhauser, W. D.; Yepes, P. (2009). "Intercomparision of Monte Carlo Radiation Transport Codes MCNPX, GEANT4, and FLUKA for Simulating Proton Radiotherapy of the Eye". Nuclear Technology. 168 (3): 810–814. doi:10.13182/NT09-A9310. PMC 2943388 . PMID 20865141.
- 1 2 Gloster, Colin Paul (2023). "Comment on "Gamma-ray spectroscopy using angular distribution of Compton scattering" [Nucl. Instr. and Meth. A 1031 (2022) 166502]". Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 1049: 167923. doi:10.1016/j.nima.2022.167923. S2CID 255262511.
- ↑ Fippel, Matthias; Soukup, Martin (2004). "A Monte Carlo dose calculation algorithm for proton therapy" . Medical Physics. 31 (8): 2263–2273. doi:10.1118/1.1769631. PMID 15377093.
