GRIP domain

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

GRIP domain
GRIP domain
	structure of a complex of the golgin-245 grip domain with arl1
Identifiers
Symbol	GRIP
Pfam	PF01465
InterPro	IPR000237
SCOP2	1upt / SCOPe / SUPFAM
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Last updated July 06, 2021

In molecular biology, the GRIP domain is a conserved protein domain. The GRIP (golgin-97, RanBP2alpha, Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. It contains a completely conserved tyrosine residue.^[1]^[2]^[3]

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References

↑ Munro S, Nichols BJ (April 1999). "The GRIP domain - a novel Golgi-targeting domain found in several coiled-coil proteins". Curr. Biol. 9 (7): 377–80. doi: 10.1016/S0960-9822(99)80166-3 . PMID 10209120. S2CID 14905585.
↑ Barr FA (April 1999). "A novel Rab6-interacting domain defines a family of Golgi-targeted coiled-coil proteins". Curr. Biol. 9 (7): 381–4. doi: 10.1016/S0960-9822(99)80167-5 . PMID 10209123. S2CID 14404566.
↑ Kjer-Nielsen L, Teasdale RD, van Vliet C, Gleeson PA (April 1999). "A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins". Curr. Biol. 9 (7): 385–8. doi: 10.1016/S0960-9822(99)80168-7 . PMID 10209125. S2CID 14342088.

This article incorporates text from the public domain Pfam and InterPro: IPR000237

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[pmid10209120-1] Munro S, Nichols BJ (April 1999). "The GRIP domain - a novel Golgi-targeting domain found in several coiled-coil proteins". Curr. Biol. 9 (7): 377–80. doi: 10.1016/S0960-9822(99)80166-3 . PMID 10209120. S2CID 14905585.

[pmid10209123-2] Barr FA (April 1999). "A novel Rab6-interacting domain defines a family of Golgi-targeted coiled-coil proteins". Curr. Biol. 9 (7): 381–4. doi: 10.1016/S0960-9822(99)80167-5 . PMID 10209123. S2CID 14404566.

[pmid10209125-3] Kjer-Nielsen L, Teasdale RD, van Vliet C, Gleeson PA (April 1999). "A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins". Curr. Biol. 9 (7): 385–8. doi: 10.1016/S0960-9822(99)80168-7 . PMID 10209125. S2CID 14342088.

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