Gail Mandel

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Gail Mandel is a senior scientist at the Vollum Institute and a professor in the Department of Biochemistry and Molecular Biology at Oregon Health & Science University. [1] From 1997 to 2016 she was an investigator with Howard Hughes Medical Institute. [2] In 2008 she was elected a member of the National Academy of Sciences. [3]

In the department of neurobiology and behavior at Stony Brook University, she identified the protein REST, which is responsible for regulation of sodium channel expression and the acquisition of cellular excitability. These discoveries have helped unlock the mechanisms through which embryonic cell types differentiate specifically into neurons. [4]

Research in the Mandel Lab is focused on understanding how neuronal cell identity is established and maintained. Most recently, the lab uncovered a role for glia in inducing neuronal dysfunction in Rett syndrome, one of the most common causes of intellectual disability in young girls.

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Oregon Health & Science University (OHSU) is a public research university focusing primarily on health sciences with a main campus, including two hospitals, in Portland, Oregon. The institution was founded in 1887 as the University of Oregon Medical Department and later became the University of Oregon Medical School. In 1974, the campus became an independent, self-governed institution called the University of Oregon Health Sciences Center, combining state dentistry, medicine, nursing, and public health programs into a single center. It was renamed Oregon Health Sciences University in 1981 and took its current name in 2001, as part of a merger with the Oregon Graduate Institute (OGI), in Hillsboro. The university has several partnership programs including a joint PharmD Pharmacy program with Oregon State University in Corvallis.

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References

  1. "Gail Mandel Ph.D. | OHSU People | OHSU". www.ohsu.edu. Retrieved 2020-02-21.
  2. "Gail Mandel". HHMI.org. Retrieved 2020-02-21.
  3. "Gail Mandel". www.nasonline.org. Retrieved 2020-02-21.
  4. "Gail Mandel". Simons Foundation. 2017-08-15. Retrieved 2020-02-21.