Related Research Articles
Monosodium glutamate (MSG), also known as sodium glutamate, is the sodium salt of glutamic acid. MSG is found naturally in some foods including tomatoes and cheese in this glutamic acid form. MSG is used in cooking as a flavor enhancer with an umami taste that intensifies the meaty, savory flavor of food, as naturally occurring glutamate does in foods such as stews and meat soups.
A supertaster is a person whose sense of taste is of far greater intensity than the average person.
Salt is a mineral composed primarily of sodium chloride (NaCl), a chemical compound belonging to the larger class of salts; salt in the form of a natural crystalline mineral is known as rock salt or halite. Salt is present in vast quantities in seawater. The open ocean has about 35 g (1.2 oz) of solids per liter of sea water, a salinity of 3.5%.
An astringent is a chemical that shrinks or constricts body tissues. The word derives from the Latin adstringere, which means "to bind fast". Calamine lotion, witch hazel, and yerba mansa, a Californian plant, are astringents, as are the powdered leaves of the myrtle.
Oleocanthal is a phenylethanoid, or a type of natural phenolic compound found in extra-virgin olive oil. It appears to be responsible for the burning sensation that occurs in the back of the throat when consuming such oil. Oleocanthal is a tyrosol ester and its chemical structure is related to oleuropein, also found in olive oil.
The Monell Chemical Senses Center is a non-profit independent scientific institute located at the University City Science Center campus in Philadelphia, in Pennsylvania. Monell conducts and publishes interdisciplinary basic research on taste, smell, and chemesthesis.
Chemesthesis is the chemical sensitivity of the skin and mucous membranes. Chemesthetic sensations arise when chemical compounds activate receptors associated with other senses that mediate pain, touch, and thermal perception. These chemical-induced reactions do not fit into the traditional sense categories of taste and smell.
Taste receptor 2 member 38 is a protein that in humans is encoded by the TAS2R38 gene. TAS2R38 is a bitter taste receptor; varying genotypes of TAS2R38 influence the ability to taste both 6-n-propylthiouracil (PROP) and phenylthiocarbamide (PTC). Though it has often been proposed that varying taste receptor genotypes could influence tasting ability, TAS2R38 is one of the few taste receptors shown to have this function.
Danielle Renee Reed is an American geneticist employed at the Monell Chemical Senses Center in Philadelphia, Pennsylvania. She is most notable for her papers regarding genetic variation in taste and obesity in mice and humans.
Dr. Alexander Bachmanov studied veterinary medicine at the Saint Petersburg Veterinary Institute, Russia (1977-1982), received his Ph.D. in biological sciences from the Pavlov Institute of Physiology in Saint Petersburg, Russia in 1990. He completed postdoctoral fellowships at the Physiological Laboratory at Cambridge University in 1993 and at the Monell Chemical Senses Center, Philadelphia, Pennsylvania, in the United States from 1994 to 1997. He later joined Monnell's faculty.
Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Wasabi Receptor, is a protein that in humans is encoded by the TRPA1 gene.
George Preti was an analytical organic chemist who worked at the Monell Chemical Senses Center in Philadelphia, Pennsylvania. For more than four decades, his research focused on the nature, origin, and functional significance of human odors. Dr. Preti's laboratory has identified characteristic underarm odorants, and his later studies centered upon a bioassay-guided approach to the identification of human pheromones, odors diagnostic of human disease, human malodor identification and suppression and examining the “odor-print” of humans.
Dr. Morley Richard Kare (1922–1990) was a physiologist and biologist.
Dr. Michael G. Tordoff is a psychobiologist working at the Monell Chemical Senses Center. His research deals with the genetics and physiology of taste and nutrition. His early work addressed (a) how and what animals learn about the value of their food, (b) how artificial sweeteners influence appetite and body weight, (c) how salt intake is regulated, and (d) how dietary calcium influences salt intake. Recently, he has been investigating calcium taste and appetite. He is the primary proponent of the notion that calcium is a basic taste, equivalent to sweet, sour, salty, and bitter.
Julie Mennella is a biopsychologist specializing in the development of food and flavor preferences in humans and the effects of alcohol and tobacco on women's health and infant development. She currently works at the Monell Chemical Senses Center in Philadelphia, PA.
Charles J. Wysocki, Ph.D., is a biologist and psychologist, and an emeritus member of the Monell Chemical Senses Center. He is notable for his work with the genetics of olfaction in mice and humans, the vomeronasal organ and the major histocompatibility complex. He has worked with Drs. George Preti and Gary Beauchamp in the past.
Pamela Dalton is a cognitive psychologist. She has a Ph.D. in experimental psychology and a Masters in Public Health. Dalton is frequently quoted by the popular press as an authority on environmental odors. She has done extensive research in the fields of sick building syndrome and multiple chemical sensitivity. In the past she has worked with the United States Department of Defense on nonlethal weapons development, or the enhancement of bad odors as weapons. She currently works at the Monell Chemical Senses Center.
The gustatory system or sense of taste is the sensory system that is partially responsible for the perception of taste (flavor). Taste is the perception produced or stimulated when a substance in the mouth reacts chemically with taste receptor cells located on taste buds in the oral cavity, mostly on the tongue. Taste, along with olfaction and trigeminal nerve stimulation, determines flavors of food and other substances. Humans have taste receptors on taste buds and other areas, including the upper surface of the tongue and the epiglottis. The gustatory cortex is responsible for the perception of taste.
Sodium ions are necessary in small amounts for some types of plants, but sodium as a nutrient is more generally needed in larger amounts by animals, due to their use of it for generation of nerve impulses and for maintenance of electrolyte balance and fluid balance. In animals, sodium ions are necessary for the aforementioned functions and for heart activity and certain metabolic functions. The health effects of salt reflect what happens when the body has too much or too little sodium. Characteristic concentrations of sodium in model organisms are: 10 mM in E. coli, 30 mM in budding yeast, 10 mM in mammalian cell and 100 mM in blood plasma.
Robert F. Margolskee is an American academic. He is the director of the Monell Chemical Senses Center and adjunct professor in the Department of Neuroscience at the Mount Sinai School of Medicine. Margolskee is also the a co-founder of Redpoint Bio. Margolskee has been a pioneer in the application of molecular biology and transgenic animal models to the study of taste transduction and chemosensation. He has made numerous seminal discoveries in the taste field, including the identification and molecular cloning of taste specific receptors, G proteins, channels and other taste signal transduction elements.
References
- ↑ Mossop, Brian (2011-07-13). "Can We Be Trained to Like Healthy Foods?". Scientific American.
- ↑ Committee on Strategies to Reduce Sodium Intake, Institute of Medicine, Strategies to Reduce Sodium Intake in the United States, Jane E. Henry and Christine L. Taylor, Eds. 2010.
- ↑ A summary of the report's recommendations can be found in "Sodium Intake Among Adults – United States, 2005−2006", Morbidity and Mortality Weekly Report (MMWR) 59: 24 ( June 25, 2010): 746-49, published by the Centers for Disease Control and Prevention.
| International | |
|---|---|
| National | |
| Academics | |
