Company type | Ltd |
---|---|
Industry | Biotechnology |
Founded | April 2000 |
Founder | Bennett Greenspan and Max Blankfeld |
Headquarters | , |
Products | Genetic tests |
Parent | myDNA Inc. |
Website | https://genebygene.com/ www |
Gene by Gene is a commercial genetic testing company based in Houston, Texas. [1] The company was owned by Bennett Greenspan and Max Blankfeld, and was the parent company of Family Tree DNA. In January 2021, Gene by Gene was acquired by US based parent company myDNA Inc. [2] Gene by Gene and Australia company myDNA Life Private Ltd. are both subsidiaries of parent company, myDNA Inc. The current Chief Executive Officer of myDNA Inc. is, Dr Lior Rauchberger.
Genealogy by Genetics, Ltd. was formed in 2000 with the creation of FamilyTreeDNA. In September 2012, Greenspan and Blankfeld restructured the company and renamed it Gene by Gene, Ltd. [3] [4] After restructuring, the business comprises four divisions; DNA DTC, DNA Findings, DNA Traits, and Family Tree DNA. [4] [5]
Family Tree DNA was the first commercial company to develop DNA testing for genealogical purposes. [6] It has been operational since April 2000.
Accreditations |
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DNA Findings: NYSDOH accredited for relationship tests |
DNA Findings: AABB accredited for relationship tests |
DNA Traits: CAP/CLIA accredited |
FTDNA: US Department of Commerce Safe Harbor certification |
Family Tree DNA originally partnered with the University of Arizona for testing. [7] [8] However, Greenspan and Blankfeld started their own testing laboratory, the Houston-based Genomics Research Center (GRC), under the Genealogy by Genetics, Ltd. parent company in 2007. [3] [9] [10] As of November 2012 [update] , the GRC processed more than five million discrete DNA tests for over 700,000 individuals and organizations. [11] [12] [13] All public participation kits from the Genographic Project are currently processed at the GRC laboratory. [14] [15] In April 2013, Gene by Gene announced it had signed an agreement with the MD Anderson Cancer Center to provide instruction, training and supervision to the center's undergraduate molecular genetic technology students. [16] [17]
With the opening of the GRC, Greenspan and Blankfeld formed additional business units between 2008 and 2012 under the Genealogy by Genetics company to sell non-genealogical genetic tests. [18] [19] They launched DNA Traits in 2008. In an interview in 2008, Greenspan said "Mendelian disorders are genealogy—we either have had a disaster in our families and therefore we know that someone carries the mutation, or they are hidden and depending upon whom we marry they might create a personal disaster for the family who is a carrier". [18] [19] DNA Traits offers Clinical Laboratory Improvement Amendments (CLIA)-regulated health diagnostic tests to identify genetic disorders and susceptibility to inherited diseases and other characteristics, and serves certified medical professionals and researchers. [20] DNA Findings offers certified relationship tests, including paternity and siblingship tests. DNA DTC was created to serve the Direct-To-Consumer (DTC) market and institutional clients such as life science companies, contract research organizations, academic institutions and public-sector research facilities. [4] [13] [21]
In January 2021 it was announced that myDNA Inc, a genomics company headquartered in Houston, Texas, had acquired Gene by Gene. [2] myDNA, Inc. also has an Australian subsidiary myDNA Life, Private Ltd., that has historically specialized in pharmacogenomics and nutrigenomics. [22] Dr Lior Rauchberger commenced his role as CEO of the newly incorporated myDNA, Inc immediately. While Gene by Gene co-founders Bennett Greenspan and Max Blankfeld joined the myDNA, Inc. Board of Directors.
Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, or through biochemical analysis to measure specific protein output. In a medical setting, genetic testing can be used to diagnose or rule out suspected genetic disorders, predict risks for specific conditions, or gain information that can be used to customize medical treatments based on an individual's genetic makeup. Genetic testing can also be used to determine biological relatives, such as a child's biological parentage through DNA paternity testing, or be used to broadly predict an individual's ancestry. Genetic testing of plants and animals can be used for similar reasons as in humans, to gain information used for selective breeding, or for efforts to boost genetic diversity in endangered populations.
Genetic genealogy is the use of genealogical DNA tests, i.e., DNA profiling and DNA testing, in combination with traditional genealogical methods, to infer genetic relationships between individuals. This application of genetics came to be used by family historians in the 21st century, as DNA tests became affordable. The tests have been promoted by amateur groups, such as surname study groups or regional genealogical groups, as well as research projects such as the Genographic Project.
deCODE genetics is a biopharmaceutical company based in Reykjavík, Iceland. The company was founded in 1996 by Kári Stefánsson with the aim of using population genetics studies to identify variations in the human genome associated with common diseases, and to apply these discoveries "to develop novel methods to identify, treat and prevent diseases."
The Genographic Project, launched on 13 April 2005 by the National Geographic Society and IBM, was a genetic anthropological study that aimed to map historical human migrations patterns by collecting and analyzing DNA samples. The final phase of the project was Geno 2.0 Next Generation. Upon retirement of the site, 1,006,542 participants in over 140 countries had joined the project.
Spencer Wells is an American geneticist, anthropologist, author and entrepreneur. He co-hosts The Insight podcast with Razib Khan. Wells led The Genographic Project from 2005 to 2015, as an Explorer-in-Residence at the National Geographic Society, and is the founder and executive director of personal genomics nonprofit The Insitome Institute.
A genealogical DNA test is a DNA-based genetic test used in genetic genealogy that looks at specific locations of a person's genome in order to find or verify ancestral genealogical relationships, or to estimate the ethnic mixture of an individual. Since different testing companies use different ethnic reference groups and different matching algorithms, ethnicity estimates for an individual vary between tests, sometimes dramatically.
Ancestry.com LLC is an American genealogy company based in Lehi, Utah. The largest for-profit genealogy company in the world, it operates a network of genealogical, historical records, and related genetic genealogy websites. It is owned by The Blackstone Group, which acquired the company on December 4, 2020, in a deal valued at $4.7 billion.
Genetic discrimination occurs when people treat others differently because they have or are perceived to have a gene mutation(s) that causes or increases the risk of an inherited disorder. It may also refer to any and all discrimination based on the genotype of a person rather than their individual merits, including that related to race, although the latter would be more appropriately included under racial discrimination. Some legal scholars have argued for a more precise and broader definition of genetic discrimination: "Genetic discrimination should be defined as when an individual is subjected to negative treatment, not as a result of the individual's physical manifestation of disease or disability, but solely because of the individual's genetic composition." Genetic Discrimination is considered to have its foundations in genetic determinism and genetic essentialism, and is based on the concept of genism, i.e. distinctive human characteristics and capacities are determined by genes.
Myriad Genetics, Inc. is an American genetic testing and precision medicine company based in Salt Lake City, Utah, United States. Myriad employs a number of proprietary technologies that permit doctors and patients to understand the genetic basis of human disease and the role that genes play in the onset, progression and treatment of disease. This information is used to guide the development of new products that assess an individual's risk for developing disease later in life, identify a patient's likelihood of responding to a particular drug therapy, assess a patient's risk of disease progression and disease recurrence, and measure disease activity.
FamilyTreeDNA is a division of Gene by Gene, a commercial genetic testing company based in Houston, Texas. FamilyTreeDNA offers analysis of autosomal DNA, Y-DNA, and mitochondrial DNA to individuals for genealogical purpose. With a database of more than two million records, it is the most popular company worldwide for Y-DNA and mitochondrial DNA, and the fourth most popular for autosomal DNA. In Europe, it is the most common also for autosomal DNA. FamilyTreeDNA as a division of Gene by Gene were acquired by MYDNA, Inc., an Australian company, in January 2021.
23andMe Holding Co. is an American personal genomics and biotechnology company based in South San Francisco, California. It is best known for providing a direct-to-consumer genetic testing service in which customers provide a saliva sample that is laboratory analysed, using single nucleotide polymorphism genotyping, to generate reports relating to the customer's ancestry and genetic predispositions to health-related topics. The company's name is derived from the 23 pairs of chromosomes in a diploid human cell.
DNAPrint Genomics was a genetics company with a wide range of products related to genetic profiling. They were the first company to introduce forensic and consumer genomics products, which were developed immediately upon the publication of the first complete draft of the human genome in the early 2000s. They researched, developed, and marketed the first ever consumer genomics product, based on "Ancestry Informative Markers" which they used to correctly identify the BioGeographical Ancestry (BGA) of a human based on a sample of their DNA. They also researched, developed and marketed the first ever forensic genomics product - DNAWITNESS - which was used to create a physical profile of donors of crime scene DNA. The company reached a peak of roughly $3M/year revenues but ceased operations in February 2009.
Personal genomics or consumer genetics is the branch of genomics concerned with the sequencing, analysis and interpretation of the genome of an individual. The genotyping stage employs different techniques, including single-nucleotide polymorphism (SNP) analysis chips, or partial or full genome sequencing. Once the genotypes are known, the individual's variations can be compared with the published literature to determine likelihood of trait expression, ancestry inference and disease risk.
MyHeritage is an online genealogy platform with web, mobile, and software products and services, introduced by the Israeli company MyHeritage in 2003. Users of the platform can obtain their family trees, upload and browse through photos, and search through over 19.9 billion historical records, among other features. In early 2021 they were acquired by Francisco Partners for $600 million.
Megan Smolenyak Smolenyak, born October 9, is an American genealogist, author, and speaker. She is also a consultant for the FBI and NCIS.
GeneTree was a family history website focused on using DNA testing to trace ancestry. A website account was free, and within their account users could order DNA tests, enter results from other testing companies, search the DNA database, create an online family tree, and correspond with family members – including sharing pictures.
Bennett C. Greenspan is an American businessman. His business ventures have covered industries from real estate to the .com boom. Though he has mainly worked in the fields of photography and genetic testing, he is best known for his pioneering work in genetic genealogy.
The International Society of Genetic Genealogy (ISOGG) is an independent non-commercial nonprofit organization of genetic genealogists run by volunteers. It was founded by a group of surname DNA project administrators in 2005 to promote DNA testing for genealogy. It advocates the use of genetics in genealogical research, provides educational resources for genealogists interested in DNA testing, and facilitates networking among genetic genealogists. As of June 2013, it comprises over 8,000 members in 70 countries. As of July 2013, regional meetings are coordinated by 20 volunteer regional coordinators located in the United States, Australia, Brazil, Canada, England, Egypt, Ireland and Russia.
Investigative genetic genealogy, also known as forensic genetic genealogy, is the emerging practice of utilizing genetic information from direct-to-consumer companies for identifying suspects or victims in criminal cases. As of December 2023, the use of this technology has solved a total of 651 criminal cases, including 318 individual perpetrators who were brought to light. There have also been 464 decedents identified, as well as 4 living Does. The investigative power of genetic genealogy revolves around the use of publicly accessible genealogy databases such as GEDMatch and Family TreeDNA. On GEDMatch, users are able to upload their genetic data from any direct-to-consumer company in an effort to identify relatives that have tested at companies other than their own.
Helix is an American population genomics company.
Once you return your genetic sample, it will be processed at Family Tree DNA, the Genographic Project's testing partner and a leading genetic genealogy company.
Family Tree DNA (FTDNA), a leading genetic testing company, partners with National Geographic on public participation testing for the project. Family Tree DNA also works with the Genographic Project to help address individual questions from public participants regarding participation and results.