Grace Bio-Labs is a global supplier of pharmaceutical, biomedical, and biochemical research products based in Bend, Oregon, United States. They develop the thin-cast nitrocellulose biochip (aka: nitrocellulose slide, nitrocellulose film slide)[1][2] and the modern hybridization and incubation chambers for glass microscope slides.[3]
Originally based near Detroit, Michigan, and founded by Charles McGrath in 1986, Grace Bio Labs relocated to Bend, Oregon in May, 1990.
With the aid of SBIR funding, Grace Bio-Labs was built on two main product types. The first is the incubation chamber for cell culture and analysis; the second is the ONCYTE Nitrocellulose Film Slide. Their incubation and hybridization chambers are fluid delivery and containment products that increase sensitivity and efficiency in fluorescence and color-based protein and cell analyte assays.[4]
The ONCYTE Nitrocellulose microporous film (nitrocellulose slide) is a biochip platform that captures and protects the 3-dimensional (tertiary) structure of biological material. Originally designed for tissue printing[1] and cell lysate capture, the film has flourished in proteomics. It is commonly used in automated and manual protein microarrays, and continues to increase throughput in proteomics research.[5]
Customer Base
Grace Bio-Labs sells to university research laboratories, biotech companies, private researchers and pharmaceutical companies. They mainly distribute to North America, Western and Central Europe, East Asia, and Southeast Asia.
1 2 Cytometrically coherent transfer of receptor proteins on microporous membrane. BioTechniques Vol. 11, No 3: 352-361, 1991.
↑ High Definition cell analysis in situ using microporous films. Cell Vision, vol. 2, No 6: 499-590, 1995.
↑ McGrath, Charles M.; Grudzien, Jennipher L.; Levine, Allan. Influence of Surface: Volume ratio of Reaction Chambers on Stoichiometry of Antibody-Based Reactions in Situ. Cell Vision, Vol 2, No. 2. 165-169, 1995.
↑ Janitz, M. The HybriWell Sealing System from Grace Bio-Labs. BioCompare, January 1, 03.
↑ Assay: Protein Microarrays on Nitrocellulose Slides. Genetic Engineering and Biotechnology News, Vol. 26, No 2. Mary Ann Liebert, Inc. Publishers: Jan 15, 2006.
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