The Grammy Award for Best R&B Instrumental Performance was awarded from 1970 to 1990 and in 1993. The award had several minor name changes:
Years reflect the year in which the Grammy Awards were presented, for works released in the previous year.
| Year | Winner(s) | Title | Nominees | Ref. | 
|---|---|---|---|---|
| 1970 | King Curtis | "Games People Play" | 
  | [1] | 
| 1971 | No Award Given | |||
| 1972 | No Award Given | |||
| 1973 | Paul Riser & The Temptations | "Papa Was a Rollin' Stone (Instrumental)" | 
  | [2] | 
| 1974 | Ramsey Lewis | "Hang On Sloopy" | 
  | [3] | 
| 1975 | MFSB | "TSOP (The Sound of Philadelphia)" | 
  | [4] | 
| 1976 | Silver Convention | "Fly, Robin, Fly" | 
  | [5] | 
| 1977 | George Benson | "Theme From Good King Bad" | 
  | [6] | 
| 1978 | The Brothers Johnson | "Q" | 
  | [7] | 
| 1979 | Earth, Wind & Fire | "Runnin'" | 
  | [8] | 
| 1980 | Earth, Wind & Fire | "Boogie Wonderland" | 
  | [9] | 
| 1981 | George Benson | "Off Broadway" | 
  | [10] | 
| 1982 | David Sanborn | "All I Need Is You" | 
  | [11] | 
| 1983 | Marvin Gaye | "Sexual Healing (Instrumental Version)" | 
  | [12] | 
| 1984 | Herbie Hancock | "Rockit" | 
  | [13] | 
| 1985 | Herbie Hancock | "Sound-System" | 
  | [14] | 
| 1986 | Ernie Watts | "Musician" | 
  | [15] | 
| 1987 | Yellowjackets | "And You Know That" | 
  | [16] | 
| 1988 | David Sanborn | "Chicago Song" | 
  | [17] | 
| 1989 | Chick Corea | "Light Years" | 
  | [18] | 
| 1990 | Soul II Soul | "African Dance" | 
  | [19] | 
| 1991 | No Award Given | |||
| 1992 | No Award Given | |||
| 1993 | Miles Davis | "Doo-Bop" | 
  | [20] |