Transfusion medicine is the branch of medicine that encompasses all aspects of the transfusion of blood and blood components including aspects related to hemovigilance. It includes issues of blood donation, immunohematology and other laboratory testing for transfusion-transmitted diseases, management and monitoring of clinical transfusion practices, patient blood management, therapeutic apheresis, stem cell collections, cellular therapy, and coagulation. Laboratory management and understanding of state and federal regulations related to blood products are also a large part of the field.
A blood donation occurs when a person voluntarily has blood drawn and used for transfusions and/or made into biopharmaceutical medications by a process called fractionation. Donation may be of whole blood, or of specific components directly (apheresis). Blood banks often participate in the collection process as well as the procedures that follow it.
AABB is an international, not-for-profit organization representing individuals and institutions involved in the field of transfusion medicine and biotherapies.
A cord blood bank is a facility which stores umbilical cord blood for future use. Both private and public cord blood banks have developed in response to the potential for cord blood in treating diseases of the blood and immune systems. Public cord blood banks accept donations to be used for anyone in need, and as such function like public blood banks. Traditionally, public cord blood banking has been more widely accepted by the medical community. Private cord blood banks store cord blood solely for potential use by the donor or donor's family. Private banks typically charge around $2,000 for the collection and around $200 a year for storage.
Intraoperative blood salvage (IOS), also known as cell salvage, is a specific type of autologous blood transfusion. Specifically IOS is a medical procedure involving recovering blood lost during surgery and re-infusing it into the patient. It is a major form of autotransfusion.
Transfusion-associated graft-versus-host disease (TA-GvHD) is a rare complication of blood transfusion, in which the immunologically competent donor T lymphocytes mount an immune response against the recipient's lymphoid tissue. These donor lymphocytes engraft, recognize recipient cells as foreign and mount an immune response against recipient tissues. Donor lymphocytes are usually identified as foreign and destroyed by the recipient's immune system. However, in situations where the recipient is severely immunocompromised, or when the donor and recipient HLA type is similar, the recipient's immune system is not able to destroy the donor lymphocytes. This can result in transfusion associated graft-versus-host disease. This is in contrast with organ/tissue transplant associated GvHD, where matching HLA reduces the incident of the complication.
The New York Blood Center (NYBC) is a community, nonprofit blood bank based in New York City. Established in 1964 by Dr. Aaron Kellner, NYBC supplies blood to approximately 200 hospitals in the Northeast United States. NYBC and its operating divisions also provide transfusion-related medical services to over 500 hospitals nationally.
Packed red blood cells, also known as packed cells, are red blood cells that have been separated for blood transfusion. The packed cells are typically used in anemia that is either causing symptoms or when the hemoglobin is less than usually 70–80 g/L. In adults, one unit brings up hemoglobin levels by about 10 g/L. Repeated transfusions may be required in people receiving cancer chemotherapy or who have hemoglobin disorders. Cross-matching is typically required before the blood is given. It is given by injection into a vein.
The New Zealand Blood Service is the provider of blood services for New Zealand. The service is a Crown entity responsible to New Zealand's Parliament and is governed by a Board appointed by the Minister of Health.
Founded in 1962, America's Blood Centers (ABC) is an association of independent non-profit blood centers that operates in Canada and the United States. ABC member organizations operate more than 600 blood collection sites providing close to 60 percent of the U.S., and a quarter of the Canadian, blood supply. These blood centers serve more than 150 million people and provide blood products and services to more than 3,500 hospitals and healthcare facilities across North America. All ABC U.S. members are licensed and regulated by the U.S. Food and Drug Administration. Kate Fry, MBA, CAE, currently leads the organization as Chief Executive Officer.
Patient Blood Management (PBM) is a set of medical practices designed to optimise the care of patients who might need a blood transfusion. Patient blood management programs use an organized framework to improve blood health, thus increasing patient safety and quality of life, reducing costs, and improving clinical outcomes. Some strategies to accomplish this include ensuring that anemia is treated prior to a surgical operation, using surgical techniques that limit blood loss, and returning blood lost during surgery to the patient via intraoperative blood salvage.
The Gift of Life Marrow Registry is a non-profit organization founded in 1991 and headquartered in Boca Raton, Florida that operates a public blood stem cell and bone marrow registry while facilitating transplants for children and adults battling life-threatening illnesses, including leukemia, lymphoma, other cancers and genetic diseases.
Carter BloodCare is a 501(c)(3) nonprofit organization headquartered in Bedford, Texas. Carter BloodCare currently provides more than 440,000 blood products annually to over 200 hospitals serving patients in more than 50 counties across North, Central and East Texas. One of the largest blood centers in operation in the United States, Carter BloodCare’s mission is “we save lives by making transfusion possible.”.
Blood donation in Bangladesh is an activity conducted by several different organisations. As of 2011, about 25% of the nation's blood supply came from voluntary donation, 20–25% from paid donors, and 50–55% from one-time donation for a specific patient.
Bloodworks Northwest is a blood bank and medical research institute headquartered in Seattle, Washington, that serves 90 hospitals in western Washington and Oregon. It has formerly been known as the Puget Sound Blood Center and King County Central Blood Bank.
Young blood transfusion refers to transfusing blood specifically from a young person into an older one with the intention of creating a health benefit. The scientific community currently views the practice as essentially pseudoscientific, with comparisons to snake oil. There are also concerns of harm. The U.S. Food and Drug Administration, in 2019, cautioned "consumers against receiving young donor plasma infusions" stating that they are an "unproven treatment".
A granulocyte transfusion is a medical procedure in which granulocytes are infused into a person's blood. Granulocyte transfusions were historically used to prevent and treat infections in people with neutropenia, but the practice declined in popularity in the 1980s. Interest in the procedure increased in the 1990s due to the development of more effective methods for harvesting granulocytes and a growing population of people with severe neutropenia from chemotherapy. However, the treatment's efficacy remains poorly understood and its use is controversial.
The Iranian Blood Transfusion Organization or acronymly IBTO is the highest and only decision-making authority in the field of supply and distribution of healthy blood and blood products in Iran. This organization was established in July 31, 1974.
The Blood Emergency Readiness Corps consists of 36 U.S.-based community blood centers that work together to provide an emergency reserve of blood products to respond to a mass shooting or mass casualty event. The program is administered by the Alliance for Community Transfusion Services (ACTS). To date, the BERC reserve has responded to supply blood products needed as a result of the Collierville Kroger shooting, the 2021 Oxford High School shooting, the Tornado outbreak of December 10–11, 2021, the Robb Elementary School Shooting on May 14, 2022, the tornado outbreak sequence primarily impacting Perrytown, TX in the Texas Panhandle on June 15, 2023, and the tornado outbreak in North Texas on May 26, 2024.
