H. Nida Sen | |
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| Alma mater | Hacettepe University Medical School (MD) Duke University School of Medicine (MHSc) |
| Scientific career | |
| Fields | Ophthalmology, clinical trials |
| Institutions | National Eye Institute |
Hatice Nida Sen is an ophthalmologist researching mechanisms involved in different forms of human uveitis. She is a clinical investigator at the National Eye Institute.
Hatice Nida Sen obtained a M.D. degree from Hacettepe University Medical School and a Master of Health Sciences from Duke University School of Medicine. She completed an ophthalmology residency at George Washington University and her uveitis and ocular immunology fellowship at the National Eye Institute (NEI). [1]
Sen is a Lasker Clinical Research Scholar and clinical investigator in the clinical and translational immunology unit at the NEI. Her research primarily focuses on understanding the mechanisms involved in different forms of human uveitis. [1] Sen designs and manages clinical trials (Phase 1, 2 and 3) at the NEI Clinical Center. She is the principal investigator on several natural history studies and clinical trials on new treatment methods for ocular inflammatory diseases. [2] Sen is a collaborator on several NIH grants. [1] [3] She is involved in the MUST (Multicenter Uveitis Systemic Treatment) trial and SUN (Standardization of Uveitis Nomenclature) working group at NEI. [2]
In addition to her research activities, Sen is a clinician and an educator. She is the director of the Uveitis Clinic and Uveitis and Ocular Immunology Fellowship Program at NEI. She is a board certified ophthalmologist and is a participating member of American Academy of Ophthalmology and international research networks. [1]
Sen has received awards for her research including senior achievement award of the American Academy of Ophthalmology, Prevention of Blindness (POB) society of Metropolitan Washington Research Award, and NIH Lasker Clinical Research Scholar Award. She is an NIH Distinguished Scholar. [4] [1]
Ophthalmology is a surgical subspecialty within medicine that deals with the diagnosis and treatment of eye disorders.
The National Eye Institute (NEI) was established in 1968. It is located in Bethesda, Maryland. The NEI is one of 27 institutes and centers of the US National Institutes of Health (NIH), an agency of the US Department of Health and Human Services. The mission of NEI is to prolong and protect the vision of the American people. The NEI conducts and performs research into treating and preventing diseases affecting the eye or vision.
Uveitis is inflammation of the uvea, the pigmented layer of the eye between the inner retina and the outer fibrous layer composed of the sclera and cornea. The uvea consists of the middle layer of pigmented vascular structures of the eye and includes the iris, ciliary body, and choroid. Uveitis is described anatomically, by the part of the eye affected, as anterior, intermediate or posterior, or panuveitic if all parts are involved. Anterior uveitis (iridocyclytis) is the most common, with the incidence of uveitis overall affecting approximately 1:4500, most commonly those between the ages of 20-60. Symptoms include eye pain, eye redness, floaters and blurred vision, and ophthalmic examination may show dilated ciliary blood vessels and the presence of cells in the anterior chamber. Uveitis may arise spontaneously, have a genetic component, or be associated with an autoimmune disease or infection. While the eye is a relatively protected environment, its immune mechanisms may be overcome resulting in inflammation and tissue destruction associated with T-cell activation.
Presumed ocular histoplasmosis syndrome (POHS) is a syndrome affecting the eye, which is characterized by peripheral atrophic chorioretinal scars, atrophy or scarring adjacent to the optic disc and maculopathy.
New York Eye and Ear Infirmary of Mount Sinai (NYEE) is located at East 14th Street and Second Avenue in lower Manhattan, New York City. Founded on August 14, 1820, NYEE is America's first specialty hospital and one of the most prominent in the fields of ophthalmology and otolaryngology in the world, providing primary inpatient and outpatient care in those specialties. Previously affiliated with New York Medical College, as of 2013 it is affiliated with the Icahn School of Medicine at Mount Sinai as a part of the membership in the Mount Sinai Health System.
The Illinois Eye & Ear Infirmary (IEEI) is a center of ophthalmology and otolaryngology research and clinical practice.
Douglas Jabs is an American ophthalmologist and an expert in clinical research in the fields of ophthalmology and uveitis.
Bascom Palmer Eye Institute is the University of Miami School of Medicine's ophthalmic care, research, and education center. The institute is based in the Health District of Miami, Florida, and has been ranked consistently as the best eye hospital and vision research center in the nation.
Reza Dana is the Claes H. Dohlman Professor of Ophthalmology, senior scientist and W. Clement Stone Clinical Research Scholar at Massachusetts Eye and Ear, Harvard Medical School, and director of the Harvard-Vision Clinical Scientist Development Program.
Emily Ying Chew, M.D., is an American ophthalmologist and an expert on the human retina with a strong clinical and research interest in diabetic eye disease and age-related eye diseases. She currently works for the National Eye Institute (NEI) at the National Institutes of Health (NIH) in Bethesda, Maryland, where she serves as deputy director of the Division of Epidemiology and Clinical Applications (DECA) and the Institute's deputy clinical director. She designs and implements Phase 1, 2 and 3 clinical trials at the NIH Clinical Center. Chew is board certified in ophthalmology.
C. Stephen Foster is an American ophthalmologist, known for his research and treatment of ocular inflammatory disease (OID) with immunomodulatory therapy. He has published over 700 peer reviewed journal articles and authored 3 textbooks in his field.
Virender Singh Sangwan is an Indian ophthalmologist and the Dr. Paul Dubord Chair professor and director of the L. V. Prasad Eye Institute, Hyderabad. Known for his research on limbal stem cells, Sangwan is the founder secretary and an adviser of the Uveitis Society of India. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 2006.
Paul A. Sieving is a former director of the National Eye Institute, part of the U.S. National Institutes of Health. Prior to joining the NIH in 2001, he served on the faculty of the University of Michigan Medical School as the Paul R. Lichter Professor of Ophthalmic Genetics. He also was the founding director of the Center for Retinal and Macular Degeneration in the university's Department of Ophthalmology and Visual Sciences.
Janine Austin Clayton is an American ophthalmologist. She is the NIH associate director for research on women’s health and director of the Office of Women's Health. Clayton was previously the deputy clinical director of the National Eye Institute.
Lim Wee Kiak is a Singaporean politician and ophthalmologist. A member of the governing People's Action Party (PAP), he has been the Member of Parliament (MP) representing the Canberra division of Sembawang GRC since 2006.
Nirali N. Shah is an American physician-scientist and pediatric hematologist-oncologist, serving as head of the hematologic malignancies section of the pediatric oncology branch at the National Cancer Institute. She researches the translation of immunotherapeutic approaches to treat high-risk hematologic malignancies in children, adolescents and young adults.
Chi-Chao Chan is a Chinese-born American ophthalmologist and physician-scientist specialized in the diagnosis and pathology of eye diseases. She joined the National Eye Institute (NEI) as a postdoctoral researcher in 1982 and remained until her retirement in 2015. Chan was promoted in 1999 to senior investigator and chief of the NEI immunopathology section and the histopathology core.
Uveitic glaucoma is most commonly a progression stage of noninfectious anterior uveitis or iritis.
Adrienne Williams Scott is an American ophthalmologist specialized in diabetic retinopathy, epiretinal membranes, and macular degeneration. She is chief of the Wilmer Eye Institute in Bel Air, Harford County, Maryland. She is an associate professor of ophthalmology at Johns Hopkins School of Medicine.
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