Han Jiahuai

Last updated
Han Jiahuai
韩家淮
Born (1960-11-15) 15 November 1960 (age 61)
Huainan, Anhui, China
Alma mater
Awards Changjiang Scholar Award (2009)
Xiamen May 1st Labor Medal (2012)
Overseas Chinese Contribution Award (2012)
Tan Jiazhen Life Science Achievement Award (2013)
Scientific career
Fieldscell biology
Institutions

Han Jiahuai is a Chinese cell biologist and professor of the School of Life Sciences, Xiamen University. He was elected as a member of the Chinese Academy of Sciences in 2013. He is also a foreign member of the American Association of Immunologists and the American Society for Microbiology. Han is mainly known for his work in innate immune signaling, especially the discovery of p38 signaling pathway. [1]

Contents

Han was born in January 1960 in Huainan, Anhui Province, China. He earned a master's degree at Peking University in 1985, and a doctor's degree at Université libre de Bruxelles in 1990. From 1990 to 1992 he did his postdoctoral research at the University of Texas Southwestern Medical Center. From 1993 to 2007 he worked at The Scripps Research Institute. He became a professor of Xiamen University in 2007, and also served as an adjunct professor at Scripps. [2] [3]

Most cited papers

Related Research Articles

Mitogen-activated protein kinase 9

Mitogen-activated protein kinase 9 is an enzyme that in humans is encoded by the MAPK9 gene.

p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell differentiation, apoptosis and autophagy. Persistent activation of the p38 MAPK pathway in muscle satellite cells due to ageing, impairs muscle regeneration.

RAF kinase

RAF kinases are a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes. The mouse sarcoma virus 3611 contains a RAF kinase-related oncogene that enhances fibrosarcoma induction. RAF is an acronym for Rapidly Accelerated Fibrosarcoma.

MAPK1

Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme that in humans is encoded by the MAPK1 gene.

MAPK14

Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene.

MAPK3

Mitogen-activated protein kinase 3, also known as p44MAPK and ERK1, is an enzyme that in humans is encoded by the MAPK3 gene.

MAPK8

Mitogen-activated protein kinase 8 is a ubiquitous enzyme that in humans is encoded by the MAPK8 gene.

MAP2K1

Dual specificity mitogen-activated protein kinase kinase 1 is an enzyme that in humans is encoded by the MAP2K1 gene.

MAPK7

Mitogen-activated protein kinase 7 also known as MAP kinase 7 is an enzyme that in humans is encoded by the MAPK7 gene.

DUSP1

Dual specificity protein phosphatase 1 is an enzyme that in humans is encoded by the DUSP1 gene.

MAP2K6

Dual specificity mitogen-activated protein kinase kinase 6 also known as MAP kinase kinase 6 or MAPK/ERK kinase 6 is an enzyme that in humans is encoded by the MAP2K6 gene, on chromosome 17.

MAP2K3

Dual specificity mitogen-activated protein kinase kinase 3 is an enzyme that in humans is encoded by the MAP2K3 gene.

MAP3K11

Mitogen-activated protein kinase kinase kinase 11 is an enzyme that in humans is encoded by the MAP3K11 gene.

Activating transcription factor 2

Activating transcription factor 2, also known as ATF2, is a protein that, in humans, is encoded by the ATF2 gene.

RPS6KA2

Ribosomal protein S6 kinase alpha-2 is an enzyme that in humans is encoded by the RPS6KA2 gene.

TAB1

Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 is an enzyme that in humans is encoded by the TAB1 gene.

MAP2K5

Dual specificity mitogen-activated protein kinase kinase 5 is an enzyme that in humans is encoded by the MAP2K5 gene.

MAP3K2

Mitogen-Activated Protein Kinase Kinase Kinase 2 also known as MEKK2 is an enzyme that in humans is encoded by the MAP3K2 gene.

MAPK11

Mitogen-activated protein kinase 11 is an enzyme that in humans is encoded by the MAPK11 gene.

Candidalysin is a cytolytic 31-amino acid α-helical amphipathic peptide toxin secreted by the opportunistic pathogen Candida albicans. This toxin is a fungal example of a classical virulence factor. Hyphal morphogenesis in C. albicans is associated with damage to host epithelial cells; during this process Candidalysin is released and intercalates in host membranes. Candidalysin promotes damage of oral epithelial cells and induces lactate dehydrogenase release and calcium ion influx. It is unique in the fact that it is the first peptide toxin to be identified in any human fungal pathogen.

References

  1. ↑ 韩家淮实验室. Xiamen University. Retrieved 27 September 2021.
  2. ↑ 韩家淮教授：低调爱国的生科人. Dingxiangyuan. Retrieved 27 September 2021.
  3. ↑ 专访韩家淮. Ebiotrade. Retrieved 27 September 2021.
  4. 1 2 3 4 Google Scholar Author page, Accessed Oct.27 2021
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