Honey Bee Genome Sequencing Consortium

Last updated

The Honey Bee Genome Sequencing Consortium is an international collaborative group of genomics scientists, scientific organisations and universities trying to decipher the genome sequences of the honey bee ( Apis mellifera ). It was formed in 2001 by American scientists. In the US, the project is funded by the National Human Genome Research Institute (a division of the National Institutes of Health (NIH)), the United States Department of Agriculture (USDA), the Texas Agricultural Experiment Station, the University of Illinois Sociogenomics Initiative, and various beekeepers association and the bee industry.

First scientific findings show that the honey bee genome may have evolved more slowly than the genomes of the fruit fly and malaria mosquito. [1] The bee genome contains versions of some important mammalian genes.

The complete genome of Apis mellifera has been sequenced and consists of 10,000 genes with approximately 236 million base pairs. The size of the genome is a tenth of the human genome. [2] The Western honey bee gene sequence showed 163 chemical receptors for smell but only 10 for taste. Besides the discovery of new genes for the use of pollen and nectar, researchers found that, in comparison with other insects, Apis mellifera has fewer genes for immunity, detoxification and the development of the cuticula. [3] The population genetic analysis showed Africa as the origin and hypothesized that the spread into Europe happened in at least two independent waves. [4]

Data from the scientific collaboration was made available on BeeBase led by Texas A&M University. [5]

BeeSpace led by the University of Illinois [6] is an effort to complete a web navigable catalog of related information.

See also

Sources

  1. Robinson, Gene and Weaver, Daniel, The Honey Bee Genome Project: A Model of Cooperation between Academia, Government, and Industry; American Bee Journal Oct. 2006 pg. 870ff
  2. Weinstock et al., Insights into social insects from the genome of the honeybee Apis mellifera Nature 443, 931-949, 2006
  3. Robertson, Hugh M. and Wanner, Kevin W. The chemoreceptor superfamily in the honey bee, Apis mellifera: Expansion of the odorant, but not gustatory, receptor family Genome Research, Volume 16, Page 1395, 2006
  4. Whitfield, Charles W. et al.: Thrice Out of Africa: Ancient and Recent Expansions of the Honey Bee, Apis mellifera. Science, Vol. 314. no. 5799, pp. 642 - 645, 2006
  5. BeeBase
  6. "BeeSpace". Archived from the original on 2016-05-22. Retrieved 2006-11-24.

Related Research Articles

<span class="mw-page-title-main">Honey bee</span> Colonial flying insect of genus Apis

A honey bee is a eusocial flying insect within the genus Apis of the bee clade, all native to mainland Afro-Eurasia. After bees spread naturally throughout Africa and Eurasia, humans became responsible for the current cosmopolitan distribution of honey bees, introducing multiple subspecies into South America, North America, and Australia.

<span class="mw-page-title-main">Africanized bee</span> Hybrid species of bee

The Africanized bee, also known as the Africanized honey bee and colloquially as the "killer bee", is a hybrid of the western honey bee, produced originally by crossbreeding of the East African lowland honey bee (A. m. scutellata) with various European honey bee subspecies such as the Italian honey bee (A. m. ligustica) and the Iberian honey bee (A. m. iberiensis).

Nosema apis is a microsporidian, a small, unicellular parasite recently reclassified as a fungus that mainly affects honey bees. It causes nosemosis, also called nosema, which is the most common and widespread of adult honey bee diseases. The dormant stage of N. apis is a long-lived spore which is resistant to temperature extremes and dehydration, and cannot be killed by freezing the contaminated comb. Nosemosis is a listed disease with the Office International des Epizooties (OIE).

Warwick Estevam Kerr was a Brazilian agricultural engineer, geneticist, entomologist, professor and scientific leader, notable for his discoveries in the genetics and sex determination of bees. The Africanized bee in the western hemisphere is directly descended from 26 Tanzanian queen bees accidentally released by a replacement bee-keeper in 1957 in Rio Claro, São Paulo in the southeast of Brazil from hives operated by Kerr, who had interbred honey bees from Europe and southern Africa.

<span class="mw-page-title-main">Cape honey bee</span> Subspecies of honey bee

The Cape honey bee or Cape bee is a southern South African subspecies of the western honey bee. They play a major role in South African agriculture and the economy of the Western Cape by pollinating crops and producing honey in the Western Cape region of South Africa. The species is endemic to the Western Cape region of South Africa on the coastal side of the Cape Fold mountain range.

<span class="mw-page-title-main">Bees and toxic chemicals</span>

Bees can suffer serious effects from toxic chemicals in their environments. These include various synthetic chemicals, particularly insecticides, as well as a variety of naturally occurring chemicals from plants, such as ethanol resulting from the fermentation of organic materials. Bee intoxication can result from exposure to ethanol from fermented nectar, ripe fruits, and manmade and natural chemicals in the environment.

BeeBase was an online bioinformatics database that hosted data related to Apis mellifera, the European honey bee along with some pathogens and other species. It was developed in collaboration with the Honey Bee Genome Sequencing Consortium. In 2020 it was archived and replaced by the Hymenoptera Genome Database.

Nosema ceranae is a microsporidian, a small, unicellular parasite that mainly affects Apis cerana, the Asiatic honey bee. Along with Nosema apis, it causes the disease nosemosis, the most widespread of the diseases of adult honey bees. N. ceranae can remain dormant as a long-lived spore which is resistant to temperature extremes and dehydration. This fungus has been shown to act in a synergistic fashion with diverse insecticides such as fipronil or neonicotinoids, by increasing the toxicity of pesticides for bees, leading to higher bee mortality. It may thus play an indirect role in colony collapse disorder. In addition, the interaction between fipronil and N. ceranae induces changes in male physiology leading to sterility.

<span class="mw-page-title-main">May Berenbaum</span> American entomologist

May Roberta Berenbaum is an American entomologist whose research focuses on the chemical interactions between herbivorous insects and their host plants, and the implications of these interactions on the organization of natural communities and the evolution of species. She is particularly interested in nectar, plant phytochemicals, honey and bees, and her research has important implications for beekeeping.

<span class="mw-page-title-main">East African lowland honey bee</span> Subspecies of honey bee native to Africa

The East African lowland honey bee is a subspecies of the western honey bee. It is native to central, southern and eastern Africa, though at the southern extreme it is replaced by the Cape honey bee. This subspecies has been determined to constitute one part of the ancestry of the Africanized bees spreading through North and South America.

<span class="mw-page-title-main">Western honey bee</span> European honey bee

The western honey bee or European honey bee is the most common of the 7–12 species of honey bees worldwide. The genus name Apis is Latin for "bee", and mellifera is the Latin for "honey-bearing" or "honey carrying", referring to the species' production of honey.

The genetics of social behavior is an area of research that attempts to address the question of the role that genes play in modulating the neural circuits in the brain which influence social behavior. Model genetic species, such as D.melanogaster and Apis mellifera, have been rigorously studied and proven to be instrumental in developing the science of genetics. Many examples of genetic factors of social behavior have been derived from a bottom-up method of altering a gene and observing the change it produces in an organism. Sociogenomics is an integrated field that accounts for the complete cellular genetic complement of an organism from a top-down approach, accounting for all biotic influences that effect behavior on a cellular level.

Gene Ezia Robinson is an American entomologist, Director of the Carl R. Woese Institute for Genomic Biology and National Academy of Sciences member. He pioneered the application of genomics to the study of social behavior and led the effort to sequence the honey bee genome. On February 10, 2009, his research was famously featured in an episode of The Colbert Report whose eponymous host referred to the honey Dr. Robinson sent him as "pharmaceutical-grade hive jive".

<span class="mw-page-title-main">Thiacloprid</span> Chemical compound

Thiacloprid is an insecticide of the neonicotinoid class. Its mechanism of action is similar to other neonicotinoids and involves disruption of the insect's nervous system by stimulating nicotinic acetylcholine receptors. Thiacloprid was developed by Bayer CropScience for use on agricultural crops to control of a variety of sucking and chewing insects, primarily aphids and whiteflies.

<i>Apis mellifera intermissa</i> Subspecies of honey bee

Apis mellifera intermissa is an African subspecies of the western honey bee.

<span class="mw-page-title-main">Robert E. Page Jr.</span> Honey bee geneticist

Robert E. Page Jr. is one of the foremost honey bee geneticists in the world and a Foundation Chair of Life Sciences of Arizona State University. An author of more than 250 research papers and articles, his work on the self-organizing regulatory networks of honey bees has been outlined in his book, "The Spirit of the Hive: The Mechanisms of Social Evolution," published by Harvard University Press in 2013. Page currently holds the titles of Arizona State University Provost Emeritus and Regents Professor Emeritus. He is also chair and professor emeritus at the University of California-Davis and an external professor at the Santa Fe Institute.

Epigenetics in insects is the role that epigenetics plays in insects.

Bartonella apis is a bacterium from the genus Bartonella. Bartonella apis was first isolated from the gut of the honey bee in 2015 by Swiss researchers at the University of Lausanne. To date, it has been found only as a gut symbiont of honey bees, including the Western honey bee, and the Eastern or Asiatic honey bee.

Alison Ruth Mercer is a New Zealand zoologist based at the University of Otago, with a particular interest in the brain physiology of bees. She was elected a member of the National Academy of Sciences in 2022.

<i>Black queen cell virus</i> Species of virus

The black queen cell virus (BQCV) is a virus that infects honey bees, specifically Apis mellifera, Apis florea, and Apis dorsata. Infection of the latter two species is more recent and can be attributed to genetic similarity and geographical closeness. It is important to learn about this virus because it is one of the most common bee viruses and bees are the most important pollinators. The agricultural industry depends on the bee's pollination to increase its economic value.