Hossein Baharvand

Last updated

Hossein Baharvand
Prof. Hossein Baharvand.png
Hossein Baharvand
Born (1972-02-25) February 25, 1972 (age 51)
Isfahan, Iran
NationalityIranian
Alma mater Shiraz University
Shahid Beheshti University
Kharazmi University
Awards Mustafa Prize 2019 [1]
Scientific career
Fields Stem cells and Developmental Biology
Institutions Royan Institute
University of Science and Culture

Hossein Baharvand is an Iranian stem cell and developmental biologist. He received his B.Sc. in biology from Shiraz University in 1994, and M.Sc. in Developmental Biology from Shahid Beheshti University, Tehran in 1996. He then obtained his Ph.D. in Cell and Developmental Biology from Khwarizmi University (former Tarbiat Moallem University) in 2004. He first joined the Royan Institute in 1995 in which he founded Royan Institute for Stem Cell Biology and Technology. [2] [3]

For the first time, he generated the mouse and human embryonic stem cells (2003) and induced pluripotent stem cells (2008) in Iran. [4] This has enabled his team to pursue many avenues of research into translational research and regenerative medicine. He has focused his research on improving the translational research and regenerative medicine mainly through the understanding of Stem Cells and Developmental Biology and Biologically inspired Engineering. [5] He has been working on pluripotent stem cell differentiation into cardiomyocytes, neural cells, hepatocytes, and the pluripotency mechanism. He has also been making numerous contributions to clinical trials and tissue-specific stem cell transplantation; as well as developing cell manufacturing. [6]

He has given numerous tutorials and invited talks in many congresses such as ISSCR (2018). [7] He is the editor of four international books which were published by Springer (2010 and 2012) and John Wiley, USA (2015). He has published 450 international[ citation needed ] and 100 national peer-reviewed papers, as well as seven chapters in international books, seventeen books in Persian, and eight translated English text books into Persian. Eight figures of his peer-reviewed publications were selected as cover pages of international journals. [8]

As of April 2022, Google Scholar reports over 20,000 citations and h-index 65 to his work. [9] He is the editorial board member of eight international journals (e.g., Journal of Biological Chemistry [10] and Scientific Reports from Nature Publishing Group [11] ). He has received 36 international and national awards including 10th (2004), 12th (2006), and 17th (2012) annual Razi research award on medical science hosted by Iran Ministry of Health and Medical Education, 26th and 32nd Khwarizmi International Award (2013 and 2019), hosted by Iran Ministry of Science, Research and Technology, 27th annual book of the year of the Islamic republic of Iran (2010), distinguished scientist in Iranian Biotechnology (2015) and Genetics (2016) national award. He is the winner of the Islamic Educational, Scientific, and Cultural Organization (ISESCO) Prize for research in the field of Biology (2010). Moreover, he was introduced as Prominent Professor in 3rd term of Allameh Tabatabaei's Award hosted by Iran vice Presidency for Science and Technology and National Elite Foundation (2014). He is the winner of the United Nations educational, scientific and cultural organization (UNESCO)-Equatorial Guinea International Prize (2014) for Research in Life Sciences aimed at improving the quality of human life with his stem cell research and its numerous applications in regenerative medicine. [12] He was also selected as one of the 20 stem cell person of the year 2017 award nominees hosted by THE NICHE site. [13] He is also the winner of the World Academy of Sciences (TWAS) prize in Biology (2019) for his fundamental contribution to the understanding of how pluripotency and differentiation are established and maintained in stem cells. [14] and has been featured as Highly Cited Researcher based on the rank in the global top 1% of scientists in ESI, Web of Science (July 2019). [15] Recently, he has been awarded the top science and technology award in the Islamic world, Mustafa Prize (2019), for his efforts to promote translational research using stem cells with the goal to improve human life. [1] He was elected as a Fellow of TWAS for his outstanding contribution to science and its promotion in the developing world (2020). [16] He also awarded national “science medal” from Medical Council of Iran (2020) and Abu Reyhan Biruni research festival on medical sciences hosted by Shahid Beheshti medical sciences university (2021). He was also awarded the honorary fellowship of the Islamic World Academy of Sciences (2022), as a Mustafa Prize laureate and in appreciation of the efforts that he has made to the field of stem cell biology. [17]

Moreover, as of now two companies are spun off from the work he initiated and directed at the Royan Institute for Stem Cell Biology and Technology including Cell Tech Pharmed as a cell factory for cell therapy, [18] and Royan Stem Cell Technology for banking of cord blood stem cells. [19]

Furthermore, he has had several efforts in publicizing the stem cell biology in Iran and in this regard he with his team established a lab entitled "Stem Cells for all" and a "mobile adventure lab" by an equipped bus. [20] The aim of these participatory teaching and learning methods is to motivate and empower learners to acquire the knowledge, skills, attitudes and values necessary to shape a sustainable future for stem cells and their potentials in regenerative medicine. He has also established “annual international summer school” program since 2010. The participants are trained by invited speakers from abroad to increase international and national interactions and training methods in this field. [21]


Controvery

As of 2020 many of his published papers came under controversy due to potential imagine fraud [22] leading to the retraction of several studies. [23] Retractions were mainly based on image problems and occurred in several journals such as Scientific reports, [24] Molecular Biotechnology, [25] Stem cell and development [26] and Cell and Tissue Research [27]

Related Research Articles

<span class="mw-page-title-main">Embryonic stem cell</span> Pluripotent stem cell of the inner cell mass of the blastocyst

Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre-implantation embryo. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells. Isolating the inner cell mass (embryoblast) using immunosurgery results in destruction of the blastocyst, a process which raises ethical issues, including whether or not embryos at the pre-implantation stage have the same moral considerations as embryos in the post-implantation stage of development.

<span class="mw-page-title-main">James Thomson (cell biologist)</span> American developmental biologist

James Alexander Thomson is an American developmental biologist best known for deriving the first human embryonic stem cell line in 1998 and for deriving human induced pluripotent stem cells (iPS) in 2007.

<span class="mw-page-title-main">Rudolf Jaenisch</span> German biologist

Rudolf Jaenisch is a Professor of Biology at MIT and a founding member of the Whitehead Institute for Biomedical Research. He is a pioneer of transgenic science, in which an animal’s genetic makeup is altered. Jaenisch has focused on creating genetically modified mice to study cancer and neurological diseases.

<span class="mw-page-title-main">Anthony Atala</span>

Anthony Atala, M.D., is an American bioengineer, urologist, and pediatric surgeon. He is the W.H. Boyce professor of urology, the founding director of the Wake Forest Institute for Regenerative Medicine, and the chair of the Department of Urology at Wake Forest School of Medicine in North Carolina. His work focuses on the science of regenerative medicine: "a practice that aims to refurbish diseased or damaged tissue using the body's own healthy cells".

<span class="mw-page-title-main">Shinya Yamanaka</span> Japanese stem cell researcher

Shinya Yamanaka is a Japanese stem cell researcher and a Nobel Prize laureate. He is the former director of Center for iPS Cell Research and Application and a professor at the Institute for Frontier Medical Sciences at Kyoto University; as a senior investigator at the UCSF-affiliated Gladstone Institutes in San Francisco, California; and as a professor of anatomy at University of California, San Francisco (UCSF). Yamanaka is also a past president of the International Society for Stem Cell Research (ISSCR).

<span class="mw-page-title-main">Janet Rossant</span> Biologist

Janet Rossant, is a developmental biologist well known for her contributions to the understanding of the role of genes in embryo development. She is a world renowned leader in developmental biology. Her current research interests focus on stem cells, molecular genetics, and developmental biology. Specifically, she uses cellular and genetic manipulation techniques to study how genes control both normal and abnormal development of early mouse embryos. Rossant has discovered information on embryo development, how multiple types of stem cells are established, and the mechanisms by which genes control development. In 1998, her work helped lead to the discovery of the trophoblast stem cell, which has assisted in showing how congenital anomalies in the heart, blood vessels, and placenta can occur.

Hans Robert Schöler is a molecular biologist and stem cell researcher. He is director at the Max Planck Institute for Molecular Biomedicine in Münster.

<span class="mw-page-title-main">Cell potency</span> Ability of a cell to differentiate into other cell types

Cell potency is a cell's ability to differentiate into other cell types. The more cell types a cell can differentiate into, the greater its potency. Potency is also described as the gene activation potential within a cell, which like a continuum, begins with totipotency to designate a cell with the most differentiation potential, pluripotency, multipotency, oligopotency, and finally unipotency.

<span class="mw-page-title-main">George Q. Daley</span>

George Quentin Daley is the Dean of the Faculty of Medicine, Caroline Shields Walker Professor of Medicine, and Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. He was formerly the Robert A. Stranahan Professor of Pediatrics at Harvard Medical School, Director of the Stem Cell Transplantation Program at Boston Children's Hospital, and an investigator of the Howard Hughes Medical Institute, Associate Director of Children's Stem Cell Program, a member of the Executive Committee of the Harvard Stem Cell Institute. He is a past president of the International Society for Stem Cell Research (2007–2008).

Mahendra Rao is a researcher known for his work involving human embryonic stem cells and other somatic stem cells. In 2011, Rao was appointed Director of the National Institutes of Health Center for Regenerative Medicine.

Satyajit Mayor (born 1963) is an Indian biologist. He serves as director of the National Centre for Biological Sciences, Bangalore. Mayor is the former director of the Institute for Stem Cell Biology and Regenerative Medicine (inStem) at Bangalore, which has a focus on the study of stem cell and regenerative biology.

Gordon M. Keller is a Canadian scientist recognized for his research on applying developmental biology findings to in vitro pluripotent stem cell differentiation. He is currently a Senior Scientist at the Ontario Cancer Institute, a Professor at the University of Toronto and the director of the McEwen Centre for Regenerative Medicine.

Lorenz Studer is a Swiss biologist. He is the founder and director of the Center for Stem Cell Biology at Memorial-Sloan Kettering Cancer Center in New York City. He is a developmental biologist and neuroscientist who is pioneering the generation of midbrain dopamine neurons for transplantation and clinical applications. His expertise in cell engineering spans a wide range of cells/tissues within the nervous system geared toward disease modeling and exploring cell replacement therapy. Currently, he is a member of the Developmental Biology Program and Department of Neurosurgery at Memorial Sloan-Kettering Cancer Center and a Professor of Neuroscience at Weill Cornell Medical College in New York City, NY.

Masayo Takahashi is a Japanese medical physician, ophthalmologist and stem cell researcher.

<span class="mw-page-title-main">Melissa Little</span> Australian scientist and academic (born 1963)

Melissa Helen Little is an Australian scientist and academic, currently Theme Director of Cell Biology, heading up the Kidney Regeneration laboratory at the Murdoch Children's Research Institute. She is also a Professor in the Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, and Program Leader of Stem Cells Australia. In January 2022, she became CEO of the Novo Nordisk Foundation Center for Stem Cell Medicine reNEW, an international stem cell research center based at University of Copenhagen, and a collaboration between the University of Copenhagen, Denmark, Murdoch Children’s Research Institute, Australia, and Leiden University Medical Center, The Netherlands.

<span class="mw-page-title-main">Maneesha S. Inamdar</span> Indian academic

Professor Maneesha Inamdar is a stem cell and developmental biologist conducting research at Bangalore, India. She is presently Director of inStem, India’s first stem cell institute. She is on deputation from the Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bangalore. She is an elected fellow of the Indian Academy of Sciences and the Indian National Science Academy and a J C Bose National Fellow.

<span class="mw-page-title-main">Paul J. Tesar</span> American developmental biologist

Paul J. Tesar is an American developmental biologist. He is the Dr. Donald and Ruth Weber Goodman Professor of Innovative Therapeutics at Case Western Reserve University School of Medicine. His research is focused on regenerative medicine.

<span class="mw-page-title-main">Christine L. Mummery</span>

Christine L. Mummery (1953) is an appointed professor of Developmental Biology at Leiden University and the head of the Department of Anatomy and Embryology at Leiden University Medical Center in the Netherlands.

<span class="mw-page-title-main">Mohamadreza Baghaban Eslaminejad</span>

Mohamadreza Baghaban Eslaminejad is the director of the Adult Stem Cell Lab and histology/embryology Professor at the Royan Institute where he held a multi-departmental professorship in bioengineering, tissue engineering, regenerative medicine, and stem cell therapy. Eslaminejad studies have been cited over 4000 times. He is best known for Hard Tissue Engineering and utilizing Mesenchymal stem cells for treatment of orthopedic diseases.

Nissim Benvenisty is Professor of Genetics, the Herbert Cohn Chair in Cancer Research and the Director of “The Azrieli Center for Stem Cells and Genetic Research” at the Alexander Silberman Institute of Life Sciences, Hebrew University.

References

  1. 1 2 "Mustafa Prize". November 9, 2019.
  2. ↑ "Royan Stem Cell – Royan institute for Stem Cell Biology and Technology (RI-SCBT)" . Retrieved March 16, 2023.
  3. ↑ "Hossein Baharvand's webpage at official portal of Royan Ins". Royan Institute . Retrieved April 28, 2014.
  4. ↑ "Royan Institute official web site: institute developments".
  5. ↑ "The Washington Times: Iran at forefront of stem cell research". The Washington Times .
  6. ↑ "Hossein Baharvand's web page at Royan Institute for Stem Cell Biology and Technology website".
  7. ↑ "ISSCR Speakers-Topics".
  8. ↑ "Hossein Baharvand's CV at Royan Institute for Stem Cell Biology and Technology website" (PDF).
  9. ↑ "Hossein Baharvand's Google Scholar" . Retrieved November 5, 2020.
  10. ↑ "JBC Editorial Board".
  11. ↑ "SREP Editorial Board".
  12. ↑ "UNESCO Prize for Research in Life Sciences".
  13. ↑ "20 Stem Cell Person of The Year 2017 Award Nominees". November 26, 2017.
  14. ↑ "Winners of 2019 TWAS Prizes".
  15. ↑ http://isid.research.ac.ir/Hossein_Baharvand
  16. ↑ "Baharvand, Hossein".
  17. ↑ "Mustafa Prize Laureates as IAS Honorary Fellows – IAS".
  18. ↑ "Cell Tech Pharmed company".
  19. ↑ "Royan Stem Cell Technology for banking of cord blood stem cells".
  20. ↑ "Stem Cells for All Lab".
  21. ↑ "Royan International Summer School".
  22. ↑ "46 papers from a Royan Institute professor". Science Integrity Digest. November 12, 2020.
  23. ↑ "PubPeer - Search publications and join the conversation". pubpeer.com.
  24. ↑ Ahmadi, Amin; Moghadasali, Reza; Ezzatizadeh, Vahid; Taghizadeh, Zeinab; Nassiri, Seyed Mahdi; Asghari-Vostikolaee, Mohammad Hassan; Alikhani, Mehdi; Hadi, Fatemeh; Rahbarghazi, Reza; Yazdi, Reza Salman; Baharvand, Hossein; Aghdami, Nasser (July 5, 2021). "Retraction Note: Transplantation of Mouse Induced Pluripotent Stem Cell-Derived Podocytes in a Mouse Model of Membranous Nephropathy Attenuates Proteinuria". Scientific Reports. 11 (1): 13831. Bibcode:2021NatSR..1113831A. doi:10.1038/s41598-021-93174-z. PMC   8257699 . PMID   34226599.
  25. ↑ Ghazizadeh, Zaniar; Rassouli, Hassan; Fonoudi, Hananeh; Alikhani, Mehdi; Talkhabi, Mahmood; Darbandi-Azar, Amir; Chen, Shuibing; Baharvand, Hossein; Aghdami, Nasser; Salekdeh, Ghasem Hosseini (September 9, 2021). "Retraction Note to: Transient Activation of Reprogramming Transcription Factors Using Protein Transduction Facilitates Conversion of Human Fibroblasts Toward Cardiomyocyte-Like Cells". Molecular Biotechnology. 64 (1): 108. doi:10.1007/s12033-021-00387-8. PMID   34499327. S2CID   237454309.
  26. ↑ "Retraction of: Long-Term Maintenance of Undifferentiated Human Embryonic and Induced Pluripotent Stem Cells in Suspension (doi.org/10.1089/scd.2010.0517)". Stem Cells and Development. 30 (21): 1092. November 1, 2021. doi:10.1089/scd.2010.0517.retract. PMID   34613840. S2CID   238421629.
  27. ↑ Oryan, Ahmad; Eslaminejad, Mohamadreza Baghaban; Kamali, Amir; Hosseini, Samaneh; Moshiri, Ali; Baharvand, Hossein (October 1, 2021). "Retraction Note to: Mesenchymal stem cells seeded onto tissue-engineered osteoinductive scaffolds enhance the healing process of critical-sized radial bone defects in rat". Cell and Tissue Research. 386 (1): 211. doi:10.1007/s00441-021-03520-w. PMID   34424398. S2CID   237268542.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.