House of Numbers: Anatomy of an Epidemic is a 2009 film directed, produced, and hosted by Brent Leung and described by him as an objective examination of the idea that HIV causes AIDS. [1] The film argues that human immunodeficiency virus (HIV) is harmless and does not cause acquired immune deficiency syndrome (AIDS), a position known as AIDS denialism. [2] [1] [3] The film's claims of impartiality have been widely rejected by scientists, and the film's claims about HIV and AIDS have been dismissed as pseudoscience and conspiracy theory masquerading as even-handed examination. [4] [5] [6]
A group of scientists interviewed for the film later complained that their comments had been misrepresented and taken out of context, and that the film promotes pseudoscience. [4] [5] The film also interviews Christine Maggiore, a prominent AIDS denialist who later died following AIDS-related conditions. [7]
Leung has declined to discuss funding for the film except to state that funders came from "all over the world". [1] [8] In the film, Leung interviews a range of scientists and AIDS denialists, most notably Christine Maggiore. At the time of filming, Maggiore was HIV-positive and appeared healthy, despite her refusal to take anti-retroviral medication, which mainstream medicine uses to slow down the rate at which HIV destroys CD4+ T-cells. As she said in the film, she refused to take the medication and did not have her daughter, Eliza Jane Scovill, tested, or provide her with medication, because she believed HIV did not cause AIDS. Rather, she believed that the medication itself caused AIDS. Maggiore's relative health, despite years of infection, is used by the film to support the idea that anti-retrovirals are unnecessary to combat, and may themselves cause, AIDS. Maggiore died of complications of advanced untreated AIDS.
The film was screened at small film festivals, including the London Raindance film Festival [9] [10] A panel discussion of the film at a Boston film festival was disrupted by Leung and other AIDS denialists in the audience, who attempted to shout down members of the panel with whom they disagreed. [1]
Both Maggiore and her daughter died of AIDS-related complications before the film's release, although their deaths are mentioned only in small print during the closing credits along with a claim that Maggiore's death was "unrelated to HIV." [5] Maggiore's daughter died in September 2005 of AIDS-related opportunistic infections, although Maggiore rejected the cause of death and argued that the coroner's report was politically motivated. [11] [12] Maggiore herself died in December 2008 from AIDS-related opportunistic infections. [13]
Eighteen scientists interviewed in the film stated that their answers to Leung's questions were selectively edited to convey a false sense that the scientific community disagrees on basic facts about HIV/AIDS. [5] Two interviewees, Neil Constantine and Robin Weiss, cite examples supporting the allegation that Leung misrepresented their words in a "surely intentional" manner. [14] Brent Leung denied taking quotes out of context. [15]
The film's promotion of AIDS denialism, a pseudoscientific movement implicated in thousands of deaths, [16] drew criticism and anger. [17] The New York Times characterized the film as "a weaselly support pamphlet for AIDS denialists", "willfully ignorant", and "a globe-trotting pseudo-investigation that should raise the hackles of anyone with even a glancing knowledge of the basic rules of reasoning." [4] The Wall Street Journal cited the film as part of "this season's fashion in conspiracy theories." [6] The Portland Oregonian criticized Leung for "not being entirely honest with viewers," and decried the film's reliance on "selective editing, anomalies and anecdotes, unsupported conclusions ... and suppression of inconvenient facts." [18]
Reaction from the scientific community was similarly negative. Lancet Infectious Diseases criticized the film's arguments, calling them a "toxic combination of misrepresentation and sophistry." [5] AIDSTruth.org, a website created by HIV researchers to address AIDS denialism, [19] criticized the film for concealing its "agenda behind a false veneer of honest inquiry", and published a rebuttal to some of the film's claims. [20] Ben Goldacre, writing in The Guardian , described House of Numbers as "a dreary and pernicious piece of Aids denialist propaganda." [3]
In February 2014 several people involved with the film filed DMCA notices against a YouTube science blogger named Myles Power, who had made a video series debunking claims made in the film. Power argued that the film was fair use as criticism and education. [21] Several commentators described the notices as attempted censorship by copyright. [22] [23] [24] The videos were restored several days later. [25]
Peter Heinz Hermann Duesberg is a German-American molecular biologist and a professor of molecular and cell biology at the University of California, Berkeley. He is known for his early research into the genetic aspects of cancer. He is a proponent of AIDS denialism, the claim that HIV does not cause AIDS.
HIV/AIDS denialism is the belief, despite conclusive evidence to the contrary, that the human immunodeficiency virus (HIV) does not cause acquired immune deficiency syndrome (AIDS). Some of its proponents reject the existence of HIV, while others accept that HIV exists but argue that it is a harmless passenger virus and not the cause of AIDS. Insofar as they acknowledge AIDS as a real disease, they attribute it to some combination of sexual behavior, recreational drugs, malnutrition, poor sanitation, haemophilia, or the effects of the medications used to treat HIV infection (antiretrovirals).
The Treatment Action Campaign (TAC) is a South African HIV/AIDS activist organisation which was co-founded by the HIV-positive activist Zackie Achmat in 1998. TAC is rooted in the experiences, direct action tactics and anti-apartheid background of its founder. TAC has been credited with forcing the reluctant government of former South African President Thabo Mbeki to begin making antiretroviral drugs available to South Africans.
David William Rasnick is an American biochemist known for his association with the AIDS denialist movement, which denies the fact that HIV is the cause of AIDS, and for his involvement with clinical trials in South Africa promoting vitamins for the treatment of AIDS, which were later ruled illegal by the South African judiciary.
Matthias Rath is a doctor, businessman, and vitamin salesman. He earned his medical degree in Germany. Rath claims that a program of nutritional supplements, including formulations that he sells, can treat or cure diabetes, cardiovascular disease, cancer, and HIV/AIDS. These claims are not supported by any reliable medical research. Rath runs the Dr. Rath Health Foundation, has been closely associated with Health Now, Inc., and founded the Dr. Rath Research Institute.
Mark Arnold Wainberg, was a Canadian HIV/AIDS researcher and HIV/AIDS activist. He was the Director of the McGill University AIDS Centre at the Montreal Jewish General Hospital and Professor of Medicine and of Microbiology at McGill University. His laboratory primarily studies HIV reverse transcriptase, the molecular basis for drug resistance, and gene therapy. He received a B.Sc. from McGill University in 1966, a Ph.D. from Columbia University in 1972, and did his post-doctoral research at Hadassah Medical School of the Hebrew University.
Christine Joy Maggiore was an HIV-positive activist and promoter of HIV/AIDS denialism. She was the founder of Alive & Well AIDS Alternatives, an organization which disputes the link between HIV and AIDS and urges HIV-positive pregnant women to avoid anti-HIV medication. Maggiore authored and self-published the book What If Everything You Thought You Knew about AIDS Was Wrong?
Alive & Well AIDS Alternatives is a 501(c) non-profit organization of AIDS denialists. The organization's stated mission is to "present information that raises questions about the accuracy of HIV tests, the safety and effectiveness of AIDS drug treatments, and the validity of most common assumptions about HIV and AIDS." The organization's founder, Christine Maggiore estimated in 2005 that the organization had assisted about 50 HIV-positive mothers in developing legal strategies to avoid having their children tested or treated for HIV.
Gary Michael Null is an American talk radio host and author who advocates pseudoscientific alternative medicine and produces a line of questionable dietary supplements.
The Durban Declaration is a statement signed by over 5,000 physicians and scientists in 2000, affirming that HIV is the cause of AIDS, seventeen years after the discovery of the Human Immunodeficiency Virus. The declaration was drafted in response to HIV/AIDS denialism, and particularly to address South African president Thabo Mbeki's support for AIDS denialists. It was written several weeks before the 2000 International AIDS Conference, held in Durban, South Africa from July 9 to 14, 2000, and was published in the journal Nature to coincide with the Durban conference. The declaration called the evidence that HIV causes AIDS "clear-cut, exhaustive and unambiguous".
Celia Ingrid Farber is an American print journalist and author who has covered a range of topics for magazines including Spin, Rolling Stone, Esquire, Harper's, Interview, Salon, Gear, New York Press, Media Post, The New York Post and Sunday Herald, and is best known for her controversial beliefs about HIV and AIDS, and a 1998 report on O. J. Simpson's post-trial life. Farber is the daughter of radio talk pioneer Barry Farber and a graduate of New York University.
In the psychology of human behavior, denialism is a person's choice to deny reality as a way to avoid believing in a psychologically uncomfortable truth. Denialism is an essentially irrational action that withholds the validation of a historical experience or event when a person refuses to accept an empirically verifiable reality.
Medical Hypotheses is a not-conventionally-peer-reviewed medical journal published by Elsevier. It was originally intended as a forum for unconventional ideas without the traditional filter of scientific peer review, "as long as are coherent and clearly expressed" in order to "foster the diversity and debate upon which the scientific process thrives." The publication of papers on AIDS denialism led to calls to remove it from PubMed, the United States National Library of Medicine online journal database. Following the AIDS papers controversy, Elsevier forced a change in the journal's leadership. In June 2010, Elsevier announced that "submitted manuscripts will be reviewed by the Editor and external reviewers to ensure their scientific merit".
The Other Side of AIDS is a 2004 pseudoscience film by Robin Scovill. Through interviews with prominent AIDS denialists and HIV-positive people who have refused anti-HIV medication, the film makes the claim that HIV is not the cause of AIDS and that HIV treatments are harmful, conclusions which are rejected by medical and scientific consensus. The film was reviewed in Variety and The Hollywood Reporter in 2004, and received additional attention in 2005, when Scovill's three-year-old daughter died of untreated AIDS.
The Perth Group is a group of HIV/AIDS denialists based in Perth, Western Australia who claim, in opposition to the scientific consensus, that the existence of HIV is not proven, and that AIDS and all the "HIV" phenomena are caused by changes in cellular redox due to the oxidative nature of substances and exposures common to all the AIDS risk groups, and are caused by the cell conditions used in the "culture" and "isolation" of "HIV".
Eliza Jane Scovill was the daughter of AIDS denialist Christine Maggiore, an HIV-positive activist who publicly questioned the link between HIV and AIDS, and supported HIV-positive pregnant women who want to avoid taking anti-HIV medication. Eliza Jane's May 16, 2005 death from AIDS, at the age of three and a half, sparked a social and legal controversy over her mother's decision not to take precautions during pregnancy and breastfeeding to prevent transmission of the virus, and her parents' decision to not have her treated for HIV infection during her life.
Seth C. Kalichman is an American clinical community psychologist and professor of social psychology at the University of Connecticut, known for his research into HIV/AIDS treatment and HIV/AIDS denialism. Kalichman is also the director of the Southeast HIV/AIDS Research & Education Project in Atlanta, Georgia, and Cape Town, South Africa, and the editor of the journal AIDS and Behavior. He is the developer of the Sexual Compulsivity Scale.
Continuum was a magazine published by an activist group of the same name who denied the existence of HIV/AIDS.
In South Africa, HIV/AIDS denialism had a significant impact on public health policy from 1999 to 2008, during the presidency of Thabo Mbeki. Mbeki criticized the scientific consensus that HIV is the cause of AIDS beginning shortly after his election to the presidency. In 2000, he organized a Presidential Advisory Panel regarding HIV/AIDS including several scientists who denied that HIV caused AIDS.
Big Pharma conspiracy theories are conspiracy theories that claim that pharmaceutical companies as a whole, especially in terms of big corporations, act in dangerously secretive and sinister ways that harm patients. This includes concealing effective treatments, perhaps even to the point of intentionally causing and/or worsening a wide range of diseases, in the pursuit of higher profits and/or other nefarious goals. The general public supposedly lives in a state of ignorance, according to such claims.