Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states and an apparent expansion of consciousness. Also referred to as classic hallucinogens or serotonergic hallucinogens, the term psychedelic is sometimes used more broadly to include various types of hallucinogens, such as those which are atypical or adjacent to psychedelia like salvia and MDMA, respectively. This article makes use of the narrower classical definition of psychedelics. Classic psychedelics generally cause specific psychological, visual, and auditory changes, and oftentimes a substantially altered state of consciousness. They have had the largest influence on science and culture, and include mescaline, LSD, psilocybin, and DMT.
Psychedelic therapy refers to the proposed use of psychedelic drugs, such as psilocybin, MDMA, LSD, and ayahuasca, to treat mental disorders. As of 2021, psychedelic drugs are controlled substances in most countries and psychedelic therapy is not legally available outside clinical trials, with some exceptions.
Psychonautics refers both to a methodology for describing and explaining the subjective effects of altered states of consciousness, including those induced by meditation or mind-altering substances, and to a research cabal in which the researcher voluntarily immerses themselves into an altered mental state in order to explore the accompanying experiences.
Set and setting, when referring to a psychedelic drug experience or the use of other psychoactive substances, means one's mindset and the physical and social environment in which the user has the experience. Set and setting are factors that can condition the effects of psychoactive substances: "Set" refers to the mental state a person brings to the experience, like thoughts, mood and expectations; "setting" to the physical and social environment. This is especially relevant for psychedelic experiences in either a therapeutic or recreational context.
A psychedelic experience is a temporary altered state of consciousness induced by the consumption of a psychedelic substance. For example, an acid trip is a psychedelic experience brought on by the use of LSD, while a mushroom trip is a psychedelic experience brought on by the use of psilocybin. Psychedelic experiences feature alterations in normal perception such as visual distortions and a subjective loss of self-identity, sometimes interpreted as mystical experiences. Psychedelic experiences lack predictability, as they can range from being highly pleasurable to frightening. The outcome of a psychedelic experience is heavily influenced by the person's mood, personality, expectations, and environment.
The Heffter Research Institute is a 501(c)(3) nonprofit organization that promotes research with classic hallucinogens and psychedelics, predominantly psilocybin, to contribute to a greater understanding of the mind and to alleviate suffering. Founded in 1993 as a virtual institute, Heffter primarily funds academic and clinical scientists and made more than $3.1 million in grants between 2011 and 2014. Heffter's recent clinical studies have focused on psilocybin-assisted treatment for end-of-life anxiety and depression in cancer patients, as well as alcohol and nicotine addiction.
Michael Kevin Pollan is an American author and journalist, who is currently Professor of the Practice of Non-Fiction and the first Lewis K. Chan Arts Lecturer at Harvard University. Concurrently, he is the Knight Professor of Science and Environmental Journalism and the director of the Knight Program in Science and Environmental Journalism at the UC Berkeley Graduate School of Journalism where in 2020 he cofounded the UC Berkeley Center for the Science of Psychedelics, in which he leads the public-education program. Pollan is best known for his books that explore the socio-cultural impacts of food, such as The Botany of Desire and The Omnivore's Dilemma.
The Marsh Chapel Experiment, also called the "Good Friday Experiment", was an experiment conducted on Good Friday, April 20, 1962 at Boston University's Marsh Chapel. Walter N. Pahnke, a graduate student in theology at Harvard Divinity School, designed the experiment under the supervision of Timothy Leary, Richard Alpert, and the Harvard Psilocybin Project. Pahnke's experiment investigated whether psilocybin would act as a reliable entheogen in religiously predisposed subjects.
Numinous means "arousing spiritual or religious emotion; mysterious or awe-inspiring"; also "supernatural" or "appealing to the aesthetic sensibility." The term was given its present sense by the German theologian and philosopher Rudolf Otto in his influential 1917 German book The Idea of the Holy. He also used the phrase mysterium tremendum as another description for the phenomenon. Otto's concept of the numinous influenced thinkers including Carl Jung, Mircea Eliade, and C. S. Lewis. It has been applied to theology, psychology, religious studies, literary analysis, and descriptions of psychedelic experiences.
The Beckley Foundation is a UK-based think tank and UN-accredited NGO, dedicated to activating global drug policy reform and initiating scientific research into psychoactive substances. The foundation is a charitable trust which collaborates with leading scientific and political institutions worldwide to design and develop research and global policy initiatives. It also investigates consciousness and its modulation from a multidisciplinary perspective, working in collaboration with scientists. The foundation is based at Beckley Park near Oxford, United Kingdom. It was founded in 1998, and is directed by Amanda Feilding, Countess of Wemyss.
Amanda Claire Marian Charteris, Countess of Wemyss and March, also known as Amanda Feilding, is an English drug policy reformer, lobbyist, and research coordinator. In 1998, she founded the Foundation to Further Consciousness, later renamed to the Beckley Foundation, a charitable trust which initiates, directs, and supports neuroscientific and clinical research into the effects of psychoactive substances on the brain and cognition. She has also co-authored over 50 papers published in peer-reviewed journals, according to the Foundation. The central aim of her research is to investigate new avenues of treatment for such mental illnesses as depression, anxiety, and addiction, as well as to explore methods of enhancing well-being and creativity.
Timothy Ferriss is an American entrepreneur, investor, author, podcaster, and lifestyle guru. He became well known through his 4-Hour self-help book series—including The 4-Hour Work Week, The 4-Hour Body, and The 4-Hour Chef—that focused on lifestyle optimizations, but he has since reconsidered this approach.
Hallucinogens are a large and diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes. Most hallucinogens can be categorized as either being psychedelics, dissociatives, or deliriants.
A psychoactive drug, psychopharmaceutical, psychoactive agent, or psychotropic drug is a chemical substance that changes the function of the nervous system and results in alterations of perception, mood, cognition, and behavior. These substances may be used medically, recreationally, for spiritual reasons, or for research. Some categories of psychoactive drugs may be prescribed by physicians and other healthcare practitioners because of their therapeutic value.
James Fadiman is an American writer known for his research on microdosing psychedelics. He co-founded the Institute of Transpersonal Psychology, which later became Sofia University.
Waking Up: A Guide to Spirituality Without Religion is a 2014 book by Sam Harris that discusses a wide range of topics including secular spirituality, the illusion of the self, psychedelics, and meditation. He attempts to show that a certain form of spirituality is integral to understanding the nature of the mind. In late September 2014, the book reached #5 on The New York Times Non-Fiction Best Sellers list.
How to Change Your Mind is a 2022 American docuseries based on the book of the same of the same name by Michael Pollan. It consists of four episodes, which were released on July 12, 2022, on Netflix and give insights into the psychedelic drugs LSD, psilocybin, MDMA and mescaline as well as their uses in psychedelic therapy. The series has been dubbed into Spanish, Hindi, Portuguese, French, Russian, German, Italian, Polish, Czech, and Hungarian.
Samin Nosrat is an Iranian-American chef, TV host, food writer and podcaster.
The Mind, Explained is a 2019 documentary streaming television series. The series is narrated by American actress Emma Stone on Season 1 and Julianne Moore on Season 2, and examines themes such as what happens inside human brains when they dream or use psychedelic drugs. The episodes explore topics including memory, dreams, anxiety, mindfulness, and psychedelics. The Mind, Explained is a spin-off of Vox's Netflix show Explained.
Trip: Psychedelics, Alienation, and Change is a 2018 nonfiction book by Tao Lin. It is his first nonfiction book, and eighth book total.
