IGHA2

IGHA2
Identifiers
Aliases	IGHA2 , immunoglobulin heavy constant alpha 2 (A2m marker)
External IDs	OMIM: 147000; GeneCards: IGHA2; OMA:IGHA2 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q32.33 Start 105,583,731 bp [1] End 105,588,395 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon duodenum rectum appendix tonsil olfactory zone of nasal mucosa spleen bone marrow cells epithelium of colon salivary gland n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 3494 n/a Ensembl ENSG00000211890 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 14: 105.58 – 105.59 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Ig alpha-2 chain C region is a protein that in humans is encoded by the IGHA2 gene. ^[3]

References

1. GRCh38: Ensembl release 89: ENSG00000211890 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker)".

Further reading

• Kerr MA (Oct 1990). "The structure and function of human IgA". The Biochemical Journal. 271 (2): 285–96. doi:10.1042/bj2710285. PMC   1149552 . PMID   2241915.
• Tsuzukida Y, Wang CC, Putnam FW (Mar 1979). "Structure of the A2m(1) allotype of human IgA--a recombinant molecule". Proceedings of the National Academy of Sciences of the United States of America. 76 (3): 1104–8. Bibcode:1979PNAS...76.1104T. doi: 10.1073/pnas.76.3.1104 . PMC   383197 . PMID   286295.
• Toraño A, Putnam FW (Feb 1978). "Complete amino acid sequence of the alpha 2 heavy chain of a human IgA2 immunoglobulin of the A2m (2) allotype". Proceedings of the National Academy of Sciences of the United States of America. 75 (2): 966–9. Bibcode:1978PNAS...75..966T. doi: 10.1073/pnas.75.2.966 . PMC   411380 . PMID   416441.
• Ellison J, Buxbaum J, Hood L (1983). "Nucleotide sequence of a human immunoglobulin C gamma 4 gene". DNA. 1 (1): 11–8. doi:10.1089/dna.1.1981.1.11. PMID   6299662.
• Ueda S, Nakai S, Nishida Y, Hisajima H, Honjo T (1984). "Long terminal repeat-like elements flank a human immunoglobulin epsilon pseudogene that lacks introns". The EMBO Journal. 1 (12): 1539–44. doi:10.1002/j.1460-2075.1982.tb01352.x. PMC   553248 . PMID   6327276.
• Hisajima H, Nishida Y, Nakai S, Takahashi N, Ueda S, Honjo T (May 1983). "Structure of the human immunoglobulin C epsilon 2 gene, a truncated pseudogene: implications for its evolutionary origin". Proceedings of the National Academy of Sciences of the United States of America. 80 (10): 2995–9. doi: 10.1073/pnas.80.10.2995 . PMC   393960 . PMID   6407005.
• Flanagan JG, Lefranc MP, Rabbitts TH (Mar 1984). "Mechanisms of divergence and convergence of the human immunoglobulin alpha 1 and alpha 2 constant region gene sequences". Cell. 36 (3): 681–8. doi:10.1016/0092-8674(84)90348-9. PMID   6421489. S2CID   54312675.
• Ellison J, Hood L (Mar 1982). "Linkage and sequence homology of two human immunoglobulin gamma heavy chain constant region genes" (PDF). Proceedings of the National Academy of Sciences of the United States of America. 79 (6): 1984–8. Bibcode:1982PNAS...79.1984E. doi: 10.1073/pnas.79.6.1984 . PMC   346106 . PMID   6804948.
• Flanagan JG, Rabbitts TH (Dec 1982). "Arrangement of human immunoglobulin heavy chain constant region genes implies evolutionary duplication of a segment containing gamma, epsilon and alpha genes". Nature. 300 (5894): 709–13. doi:10.1038/300709a0. PMID   6817141. S2CID   4335031.
• Bunkenborg J, Pilch BJ, Podtelejnikov AV, Wiśniewski JR (Feb 2004). "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry". Proteomics. 4 (2): 454–65. doi:10.1002/pmic.200300556. PMID   14760718. S2CID   29261009.
• Kristiansen TZ, Bunkenborg J, Gronborg M, Molina H, Thuluvath PJ, Argani P, Goggins MG, Maitra A, Pandey A (Jul 2004). "A proteomic analysis of human bile". Molecular & Cellular Proteomics. 3 (7): 715–28. doi: 10.1074/mcp.M400015-MCP200 . PMID   15084671.
• Ramachandran P, Boontheung P, Xie Y, Sondej M, Wong DT, Loo JA (Jun 2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry". Journal of Proteome Research. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID   16740002.
• Bernhard OK, Kapp EA, Simpson RJ (Mar 2007). "Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides". Journal of Proteome Research. 6 (3): 987–95. doi:10.1021/pr0604559. PMID   17330941.