IGHG4

IGHG4
Identifiers
Aliases	IGHG4 , immunoglobulin heavy constant gamma 4 (G4m marker)
External IDs	OMIM: 147130; GeneCards: IGHG4; OMA:IGHG4 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q32.33 Start 105,620,506 bp [1] End 105,626,066 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in appendix duodenum spleen gallbladder bone marrow cells mucosa of transverse colon lymph node rectum right lobe of liver right coronary artery n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 3503 n/a Ensembl ENSG00000211892 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 14: 105.62 – 105.63 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Ig gamma-4 chain C region is a protein that in humans is encoded by the IGHG4 gene. ^[3]

See also

• Immunoglobulin heavy chain (IGH)
• Immunoglobulin G (IgG)
  • Subclasses of IgG, IgG4 is encoded by this gene
• IgG4-related disease

References

1. GRCh38: Ensembl release 89: ENSG00000211892 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker)".

Further reading

• McLean GR, Nakouzi A, Casadevall A, Green NS (Oct 2000). "Human and murine immunoglobulin expression vector cassettes". Molecular Immunology. 37 (14): 837–45. doi:10.1016/S0161-5890(00)00101-2. PMID   11257305.
• Ellison J, Hood L (Mar 1982). "Linkage and sequence homology of two human immunoglobulin gamma heavy chain constant region genes" (PDF). Proceedings of the National Academy of Sciences of the United States of America. 79 (6): 1984–8. Bibcode:1982PNAS...79.1984E. doi: 10.1073/pnas.79.6.1984 . PMC   346106 . PMID   6804948.
• Flanagan JG, Lefranc MP, Rabbitts TH (Mar 1984). "Mechanisms of divergence and convergence of the human immunoglobulin alpha 1 and alpha 2 constant region gene sequences". Cell. 36 (3): 681–8. doi:10.1016/0092-8674(84)90348-9. PMID   6421489. S2CID   54312675.
• Hisajima H, Nishida Y, Nakai S, Takahashi N, Ueda S, Honjo T (May 1983). "Structure of the human immunoglobulin C epsilon 2 gene, a truncated pseudogene: implications for its evolutionary origin". Proceedings of the National Academy of Sciences of the United States of America. 80 (10): 2995–9. doi: 10.1073/pnas.80.10.2995 . PMC   393960 . PMID   6407005.
• Ueda S, Nakai S, Nishida Y, Hisajima H, Honjo T (1984). "Long terminal repeat-like elements flank a human immunoglobulin epsilon pseudogene that lacks introns". The EMBO Journal. 1 (12): 1539–44. doi:10.1002/j.1460-2075.1982.tb01352.x. PMC   553248 . PMID   6327276.
• Ellison J, Buxbaum J, Hood L (1983). "Nucleotide sequence of a human immunoglobulin C gamma 4 gene". DNA. 1 (1): 11–8. doi:10.1089/dna.1.1981.1.11. PMID   6299662.
• Pink JR, Buttery SH, De Vries GM, Milstein C (Mar 1970). "Human immunoglobulin subclasses. Partial amino acid sequence of the constant region of a gamma 4 chain". The Biochemical Journal. 117 (1): 33–47. doi:10.1042/bj1170033. PMC   1178827 . PMID   4192699.