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| Content | |
| Description | genomic resources of human cell lines for identification. |
| Organisms | Homo sapiens |
| Contact | |
| Research center | Academia Sinica |
| Laboratory | Institute of Biomedical Sciences |
| Authors | Cheng-Kai Shiau |
| Primary citation | Shiau & al. (2011) [1] |
| Release date | 2010 |
| Access | |
| Website | http://igrcid.ibms.sinica.edu.tw |
IGRhCellID is a database of cell lines using some common tools to reduce cell lines misidentification. [1]
The proteome is the entire set of proteins that is, or can be, expressed by a genome, cell, tissue, or organism at a certain time. It is the set of expressed proteins in a given type of cell or organism, at a given time, under defined conditions. Proteomics is the study of the proteome.
Object–relational mapping in computer science is a programming technique for converting data between incompatible type systems using object-oriented programming languages. This creates, in effect, a "virtual object database" that can be used from within the programming language. There are both free and commercial packages available that perform object–relational mapping, although some programmers opt to construct their own ORM tools.
HeLa is an immortal cell line used in scientific research. It is the oldest and most commonly used human cell line. The line is named after and derived from cervical cancer cells taken on February 8, 1951, from Henrietta Lacks, a 31-year-old African-American mother of five, who died of cancer on October 4, 1951. The cell line was found to be remarkably durable and prolific, which allows it to be used extensively in scientific study.
Calcium ions (Ca2+) contribute to the physiology and biochemistry of organisms' cells. They play an important role in signal transduction pathways, where they act as a second messenger, in neurotransmitter release from neurons, in contraction of all muscle cell types, and in fertilization. Many enzymes require calcium ions as a cofactor, including several of the coagulation factors. Extracellular calcium is also important for maintaining the potential difference across excitable cell membranes, as well as proper bone formation.
A GIS file format is a standard of encoding geographical information into a computer file. They are created mainly by government mapping agencies or by GIS software developers.
In a relational database, a column is a set of data values of a particular type, one value for each row of the database. A column may contain text values, numbers, or even pointers to files in the operating system. Columns typically contain simple types, though some relational database systems allow columns to contain more complex data types, such as whole documents, images, or even video clips. A column can also be called an attribute.
Cell culture is the process by which cells are grown under controlled conditions, generally outside their natural environment. After the cells of interest have been isolated from living tissue, they can subsequently be maintained under carefully controlled conditions. These conditions vary for each cell type, but generally consist of a suitable vessel with a substrate or medium that supplies the essential nutrients (amino acids, carbohydrates, vitamins, minerals), growth factors, hormones, and gases (CO2, O2), and regulates the physio-chemical environment (pH buffer, osmotic pressure, temperature). Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be grown free floating in a medium as a suspension culture. The lifespan of most cells is genetically determined, but some cell culturing cells have been “transformed” into immortal cells which will reproduce indefinitely if the optimal conditions are provided.
Biological immortality is a state in which the rate of mortality from senescence is stable or decreasing, thus decoupling it from chronological age. Various unicellular and multicellular species, including some vertebrates, achieve this state either throughout their existence or after living long enough. A biologically immortal living being can still die from means other than senescence, such as through injury, poison, disease, lack of available resources, or changes to environment.
The scleraxis protein is a member of the basic helix-loop-helix (bHLH) superfamily of transcription factors. Currently two genes have been identified to code for identical scleraxis proteins.
Marc Guy Albert Marie Lacroix is a biochemist and a researcher who specializes in breast cancer biology, metastasis and therapy.
Most of the eicosanoid receptors are integral membrane protein G protein-coupled receptors (GPCRs) that bind and respond to eicosanoid signaling molecules. Eicosanoids are rapidly metabolized to inactive products and therefore are short-lived. Accordingly, the eicosanoid-receptor interaction is typically limited to a local interaction: cells, upon stimulation, metabolize arachidonic acid to an eicosanoid which then binds cognate receptors on either its parent cell or on nearby cells to trigger functional responses within a restricted tissue area, e.g. an inflammatory response to an invading pathogen. In some cases, however, the synthesized eicosanoid travels through the blood to trigger systemic or coordinated tissue responses, e.g. prostaglandin (PG) E2 released locally travels to the hypothalamus to trigger a febrile reaction. An example of a non-GPCR receptor that binds many eicosanoids is the PPAR-γ nuclear receptor.
The Microsoft Office XML formats are XML-based document formats introduced in versions of Microsoft Office prior to Office 2007. Microsoft Office XP introduced a new XML format for storing Excel spreadsheets and Office 2003 added an XML-based format for Word documents.
ID4 is a protein coding gene. In humans, it encodes for the protein known as DNA-binding protein inhibitor ID-4. This protein is known to be involved in the regulation of many cellular processes during both prenatal development and tumorigenesis. This is inclusive of embryonic cellular growth, senescence, cellular differentiation, apoptosis, and as an oncogene in angiogenesis.
The Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH was founded 1969 as the national culture collection in Germany. This independent non-profit organization is dedicated to the acquisition, characterization, identification, preservation, distribution of Bacteria, Archea, fungi, plasmids, bacteriophages, human and animal cell lines, plant cell cultures and plant viruses. The organization is member of the German Wissenschaftsgemeinschaft Gottfried Wilhelm Leibniz and of worldwide organizations like the European Culture Collections' Organisation (ECCO), the World Federation for Culture Collections (WFCC), and the Global Biodiversity Information Facility (GBIF).
GeneCards is a database of human genes that provides genomic, proteomic, transcriptomic, genetic and functional information on all known and predicted human genes. It is being developed and maintained by the Crown Human Genome Center at the Weizmann Institute of Science.
A GSM Cell ID (CID) is a generally unique number used to identify each base transceiver station (BTS) or sector of a BTS within a location area code (LAC) if not within a GSM network.
An immortalised cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cells can therefore be grown for prolonged periods in vitro. The mutations required for immortality can occur naturally or be intentionally induced for experimental purposes. Immortal cell lines are a very important tool for research into the biochemistry and cell biology of multicellular organisms. Immortalised cell lines have also found uses in biotechnology.
OpenCellID is a collaborative community project that collects GPS positions of cell towers and their corresponding location area identity.
A Discrete Global Grid (DGG) is a mosaic which covers the entire Earth's surface. Mathematically it is a space partitioning: it consists of a set of non-empty regions that form a partition of the Earth's surface. In a usual grid-modeling strategy, to simplify position calculations, each region is represented by a point, abstracting the grid as a set of region-points. Each region or region-point in the grid is called a cell.
The NCI-60 cancer cell line panel is a group of 60 human cancer cell lines used by the National Cancer Institute (NCI) for the screening of compounds to detect potential anticancer activity.
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