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References
- ↑ Cheney, Catherine (3 December 2020). "The Gates Foundation leans into disease modeling". Devex. Retrieved 30 December 2020.
- 1 2 Sandi Doughton (March 15, 2020). "How big will the coronavirus outbreak get? This Bellevue scientist is figuring that out". The Seattle Times.
- ↑ Eaton et al. 2015.
- ↑ Ross Reynolds (March 14, 2014). "Improving The Battle Against Infectious Diseases" (audio). Seattle: KUOW-FM.
- ↑ Bershteyn et al. 2018.
- ↑ Tess Riski (March 31, 2020). "How Bad Will Oregon's Outbreak Get? It Depends on Which Experts You Ask". Willamette Week .
Two reliable studies show divergent COVID-19 outcomes in Oregon.
- ↑ Todd Bishop; Taylor Soper (April 15, 2020), "As Washington state COVID cases keep falling, here's the data driving the ongoing 'stay home' order", Geekwire
- ↑ Gillian Friedman (April 3, 2020). "Coronavirus: How the West Coast is winning, and what Utah can learn". Deseret News . Salt Lake City.
- ↑ Kerr, Cliff; Mistry, Dina; et al. (2021). "Covasim: an agent-based model of COVID-19 dynamics and interventions". medRxiv 10.1101/2020.05.10.20097469v1 .
Sources
- Jeffrey W Eaton; Nicolas Bacaër; Anna Bershteyn; Valentina Cambiano; Anne Cori; Rob E Dorrington; et al. (October 2015), "Assessment of epidemic projections using recent HIV survey data in South Africa: a validation analysis of ten mathematical models of HIV epidemiology in the antiretroviral therapy era", The Lancet, 3 (10): e598–e608, doi: 10.1016/S2214-109X(15)00080-7 , PMID 26385301
- Bershteyn, Anna; Gerardin, Jaline; Bridenbecker, Daniel; Lorton, Christopher W; Bloedow, Jonathan; Baker, Robert S; Chabot-Couture, Guillaume; Chen, Ye; Fischle, Thomas; Frey, Kurt; Gauld, Jillian S; Hu, Hao; Izzo, Amanda S; Klein, Daniel J; Lukacevic, Dejan; McCarthy, Kevin A; Miller, Joel C; Ouedraogo, Andre Lin; Perkins, T Alex; Steinkraus, Jeffrey; ten Bosch, Quirine A; Ting, Hung-Fu; Titova, Svetlana; Wagner, Bradley G; Welkhoff, Philip A; Wenger, Edward A; Wiswell, Christian N (2018), "Implementation and applications of EMOD, an individual-based multi-disease modeling platform", Pathogens and Disease , 76 (5), doi: 10.1093/femspd/fty059 , ISSN 2049-632X, PMC 6067119 , PMID 29986020
