The Institute of Advanced Virology (IAV) [1] has been established by the Government of Kerala [2] through Kerala Biotechnology Commission (KBC) of Kerala State Council for Science Technology and Environment (KSCSTE) on the wake of the 2018 Nipah virus outbreak in Kerala. [3]
Established | 2019 |
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Location |
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Website | Official Website |
The institute is located in the Bio 360 Life Sciences Park at Thiruvananthapuram, Kerala, India. The foundation stone of the IAV was laid on 30 May 2018 and inaugurated on 9 February 2019. [4] The institute is also affiliated to the Global Virus Network (GVN). [5]
Currently The institute comprises the following divisions:
Henipavirus is a genus of negative-strand RNA viruses in the family Paramyxoviridae, order Mononegavirales containing six established species, and numerous others still under study. Henipaviruses are naturally harboured by several species of small mammals, notably pteropid fruit bats, microbats of several species, and shrews. Henipaviruses are characterised by long genomes and a wide host range. Their recent emergence as zoonotic pathogens capable of causing illness and death in domestic animals and humans is a cause of concern.
Nipah virus is a bat-borne, zoonotic virus that causes Nipah virus infection in humans and other animals, a disease with a very high mortality rate (40-75%). Numerous disease outbreaks caused by Nipah virus have occurred in South East Africa and Southeast Asia. Nipah virus belongs to the genus Henipavirus along with the Hendra virus, which has also caused disease outbreaks.
Pinarayi Vijayan is an Indian politician who is the current Chief Minister of Kerala, serving since 25 May 2016. A member of the Politburo of the Communist Party of India (Marxist), he is the longest-serving secretary of the Kerala State Committee of the CPI(M) (1998–2015). He also served in the government of Kerala as Minister of Electric Power and Co-operatives from 1996 to 1998. Vijayan won a seat in the May 2016 Kerala Legislative Assembly election as the CPI(M) candidate for Dharmadom constituency and was selected as the leader of the Left Democratic Front (LDF) and became the 12th Chief Minister of Kerala. He is the first chief minister from Kerala to be re-elected after completing a full term in office. In 2022, he also became the longest-continuous serving chief minister of Kerala surpassing C. Achutha Menon who had been the first to remain in office for 2364 consecutive days.
The National Institute of Virology in Pune, India is an Indian virology research institute and part of the Indian Council of Medical Research (ICMR). It was previously known as 'Virus Research Centre' and was founded in collaboration with the Rockefeller Foundation. It has been designated as a WHO H5 reference laboratory for SE Asia region.
Influenza, commonly known as "the flu" or just "flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin from one to four days after exposure to the virus and last for about 2–8 days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia, which can be caused by the virus or by a subsequent bacterial infection. Other complications of infection include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease.
The Vaccine Research Center (VRC), is an intramural division of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), US Department of Health and Human Services (HHS). The mission of the VRC is to discover and develop both vaccines and antibody-based products that target infectious diseases.
Zika virus is a member of the virus family Flaviviridae. It is spread by daytime-active Aedes mosquitoes, such as A. aegypti and A. albopictus. Its name comes from the Ziika Forest of Uganda, where the virus was first isolated in 1947. Zika virus shares a genus with the dengue, yellow fever, Japanese encephalitis, and West Nile viruses. Since the 1950s, it has been known to occur within a narrow equatorial belt from Africa to Asia. From 2007 to 2016, the virus spread eastward, across the Pacific Ocean to the Americas, leading to the 2015–2016 Zika virus epidemic.
Kerala State Council for Science, Technology and Environment (KSCSTE) is an autonomous body constituted by the Government of Kerala in November 2002 to encourage and promote science and technology-related activities in Kerala State. Prior to the establishment of KSCSTE, the body responsible for carrying out similar work was the State Committee for Science, Technology and Environment (STEC) established in 1972. KSCSTE was formed by restructuring STEC in concurrence with the Science Policy of Government of India.
Favipiravir, sold under the brand name Avigan among others, is an antiviral medication used to treat influenza in Japan. It is also being studied to treat a number of other viral infections, including SARS-CoV-2. Like the experimental antiviral drugs T-1105 and T-1106, it is a pyrazinecarboxamide derivative.
The Viral Research and Diagnostic Laboratories (VRDL) scheme was introduced by the Government of India under Department of Health Research - Indian Council of Medical Research as outbreaks of viral agents is very common in India. The Central government announced the establishment of 166 research and diagnostics laboratories in 2016. By 2019, 103 new VRDLs were established across India, taking the total count to 105.
The Global Virus Network (GVN) is an international coalition of medical virologists whose goal is to help the international medical community by improving the detection and management of viral diseases. The network was founded in 2011 by Robert Gallo in collaboration with William Hall and Reinhard Kurth, and 24 countries were members of the network as of 2015. The GVN fosters research into viruses that cause human disease to promote the development of diagnostics, antiviral drugs and vaccines, and its mission includes strengthening scientific training and response mechanisms to viral outbreaks. The GVN has organized task forces for chikungunya, human T-lymphotropic virus, and Zika. The network is headquartered at the Institute of Human Virology at the University of Maryland School of Medicine, and Gallo serves as its scientific director.
First Pinarayi Vijayan ministry is the Council of Ministers headed by Pinarayi Vijayan that was formed after the Left Democratic Front (LDF) won the 2016 Kerala Legislative Assembly elections. The Council assumed office on 25 May 2016. The ministry had a total of 19 ministers in the Cabinet at the time of swearing-in compared to 21 ministers in the previous government. Pinarayi Vijayan sworn in as 22nd Chief Minister of Kerala, 12th person to hold this position. Chief Minister Pinarayi Vijayan on 3 May 2021 submitted the resignation of the Council of Ministers headed by him to Governor Arif Mohammed Khan after winning a historic victory in the 15th legislative assembly elections by winning 99 of the 140 seats in the Assembly.
K. K. Shailaja is an Indian politician and former Health Minister of Kerala who hails from Kannur district.
A Nipah virus infection is a viral infection caused by the Nipah virus. Symptoms from infection vary from none to fever, cough, headache, shortness of breath, and confusion. This may worsen into a coma over a day or two, and 50 to 75% of those infected die. Complications can include inflammation of the brain and seizures following recovery.
There have been several outbreaks of Nipah virus in Kerala, some of which have been traced to fruit bats. The National Institute of Virology in Pune confirmed the first case of Nipah virus in Kerala in May 2018.
Bio 360 Life Sciences Park is a Biotechnology and Life Sciences park in the city of Thiruvananthapuram, India. Established in 2013, by the Government of Kerala, the Phase I of the park is spread over 75 acres (30 ha). An additional 128.5 acres (52.0 ha) of land is being undertaken by the government of Kerala as the Phase 2 development of the park.
Jacob Vadakkanchery is a naturopath, Gandhian, and social worker based in Kerala, India. He is the former chairman of Nature Life International which has several nature cure hospitals across Kerala. He is known for campaigning against liquor shops, junk foods, chemical-based farming methods, preventive medicines, and vaccination. He has authored four books about naturopathy and lifestyle. He has been arrested for pseudo-treatments and for spreading false information about leptospirosis and Nipah virus.
Daniel R. Lucey is an American physician, researcher, senior scholar and adjunct professor of infectious diseases at Georgetown University, and a research associate in anthropology at the Smithsonian National Museum of Natural History, where he has co-organised an exhibition on eight viral outbreaks.
William W. Hall is the chair of medical microbiology and professor emeritus at the Centre for Research in Infectious Diseases at University College Dublin.
Pragya D. Yadav is an Indian scientist at the ICMR-National Institute of Virology (NIV), who is known for her research contributions in the field of communicable diseases and highly pathogenic viral infections, such as Crimean–Congo hemorrhagic fever (CCHF), Nipah, Ebola, leading to improvising national public health surveillance policy for interventions and management. Yadav is among the scientists who detected the first three COVID-19 pandemic cases in India. She headed the team that developed Covaxin, the first indigenous COVID-19 vaccine in India