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The Institute of Biophysics, Chinese Academy of Sciences, based in Beijing, China, focuses on biophysically oriented basic research in the life sciences. It was established by Bei Shizhang in 1958, from the former Beijing Experimental Biology Institute founded in 1957. Xu Tao is the current Director.
The main research focus of the Institute is on the fields of protein science and brain & cognitive sciences. The Institute has two National Key Laboratories—"The National Laboratory of Biomacromolecules" and "The State Laboratory of Brain and Cognitive Sciences". The establishment of the National Laboratory of Protein Science was given approval by China's Ministry of Science and Technology (MOST) in December 2006. Research in the field of protein science emphasizes the following areas: 3D-structure and function of proteins, bio-membranes and membrane proteins, protein translation and folding, protein interaction networks, the molecular basis of infection and immunity, the molecular basis of sensation and cognition, protein and peptide drugs, and new techniques and methods in protein science research. Research areas in the brain and cognitive sciences include neural processes and mechanisms in complex cognition, expression of visual perception and attention, neural mechanisms of perceptional information processing, and dysfunction in brain cognition.
The Institute has received National Natural Science Foundation, '973', '863', 'Knowledge Innovation Program', and other major research grants, supporting outstanding research in a range of areas. The achievements of the Institute in terms of awards, publications, patents, and applied research maintain the Institute at the highest level nationally, and it has worldwide recognition for research in the life sciences. Among other connections, since 2008 it has hosted an intensive course in macromolecular crystallography as a resource closely modeled on the course at Cold Spring Harbor Laboratory on Long Island, USA, and involving both US and Chinese instructors.
The Biophysical Society of China is affiliated with the Institute. It takes responsibility for editing two core national natural science journals, namely Progress in Biochemistry & Biophysics and Acta Biophysica Sinica. Of these, Progress in Biochemistry & Biophysics is indexed in the SCI-E database. The institute has a library (1100 square meters) with 28,000 books, more than 33,000 journals, and 11 databases. Library users can use the internet to access about 2,500 foreign e-journals.
The Institute has a research team, with about 400 staff members, 500 graduate students, and 60 visiting scholars and post-docs. Within the scientific staff, there are 89 Principal Investigators and three technical specialists, of whom 14 are members of the Chinese Academy of Sciences. 28 have received awards from the "100 Talents Program of the Chinese Academy of Sciences" and 30 have received the "National Outstanding Young Scientists Award". [1]
Hartmut Michel is a German biochemist, who received the 1988 Nobel Prize in Chemistry for determination of the first crystal structure of an integral membrane protein, a membrane-bound complex of proteins and co-factors that is essential to photosynthesis.
Jean-Pierre Changeux is a French neuroscientist known for his research in several fields of biology, from the structure and function of proteins, to the early development of the nervous system up to cognitive functions. Although being famous in biological sciences for the MWC model, the identification and purification of the nicotinic acetylcholine receptor and the theory of epigenesis by synapse selection are also notable scientific achievements. Changeux is known by the non-scientific public for his ideas regarding the connection between mind and physical brain. As put forth in his book, Conversations on Mind, Matter and Mathematics, Changeux strongly supports the view that the nervous system functions in a projective rather than reactive style and that interaction with the environment, rather than being instructive, results in the selection amongst a diversity of preexisting internal representations.
Stephen Grossberg is a cognitive scientist, theoretical and computational psychologist, neuroscientist, mathematician, biomedical engineer, and neuromorphic technologist. He is the Wang Professor of Cognitive and Neural Systems and a Professor Emeritus of Mathematics & Statistics, Psychological & Brain Sciences, and Biomedical Engineering at Boston University.
Nancy Gail Kanwisher FBA is the Walter A Rosenblith Professor of Cognitive Neuroscience in the Department of Brain and Cognitive Sciences at the Massachusetts Institute of Technology and a researcher at the McGovern Institute for Brain Research. She studies the neural and cognitive mechanisms underlying human visual perception and cognition.
Wayne L. Hubbell is an American biochemist and member of the National Academy of Sciences. He is Professor of Biochemistry and Jules Stein Professor of Ophthalmology at the University of California, Los Angeles. His research focuses on the visual system, and is primarily supported by a grant from the National Eye Institute.
David S. Cafiso is an American biochemist and a professor of chemistry at the University of Virginia. His research focuses on membrane proteins and cell signaling, and is primarily supported by grants from the National Institute of Health.
John Kuriyan is the dean of basic sciences and a professor of biochemistry at Vanderbilt University School of Medicine. He was formerly the Chancellor's Professor at the University of California, Berkeley in the departments of molecular and cell biology (MCB) and chemistry, a faculty scientist in Berkeley Lab's physical biosciences division, and a Howard Hughes Medical Institute investigator. He is a member of the National Academy of Sciences and he has also been on the Life Sciences jury for the Infosys Prize in 2009, 2019 and 2020.
Steven G. Clarke, an American biochemist, is a director of the UCLA Molecular Biology Institute, a professor of chemistry and biochemistry at UCLA biochemistry department. Clarke heads a laboratory at UCLA's department of chemistry and biochemistry. Clarke is famous for his work on molecular damage and discoveries of novel molecular repair mechanisms.
Stephen Crain is the director of the ARC Centre of Excellence in Cognition and its Disorders (CCD), and a distinguished professor at Macquarie University in the Department of Linguistics. He is a well-known researcher specializing in language acquisition, focusing specifically on syntax and semantics. Crain views language acquisition as based on language-specific faculties, and he conducts his research in the tradition of Chomskyan generative grammar. Recently, Crain has proposed that language is based on a universal logical system, and he has begun to explore the neural correlates of language acquisition from a cross-linguistic perspective using magnetoencephalography (MEG). Crain received a BA in philosophy from the University of California, Los Angeles in 1971 and a PhD in cognitive science with an emphasis in linguistics from the University of California, Irvine in 1980. Crain was employed as a professor of linguistics at the University of Connecticut from 1986 to 1995. During that time he was also a senior scientist at Haskins Laboratories in New Haven, Connecticut. After leaving UConn, he took a position as professor of linguistics at the University of Maryland, College Park, from 1995 to 2003, before accepting a position as a professor of cognitive science at Macquarie in 2004, where he has remained since. He was deputy director of the Macquarie Centre for Cognitive Science from 2004 until 2010, and director of the Centre for Language Sciences from 2007 until 2010. He led the successful bid for an ARC Centre of Excellence in Cognition and its Disorders, which is funded from 2011 until 2017.
The Troland Research Awards are an annual prize given by the United States National Academy of Sciences to two researchers in recognition of psychological research on the relationship between consciousness and the physical world. The areas where these award funds are to be spent include but are not limited to areas of experimental psychology, the topics of sensation, perception, motivation, emotion, learning, memory, cognition, language, and action. The award preference is given to experimental work with a quantitative approach or experimental research seeking physiological explanations.
Wayne A. Hendrickson is an American biophysicist and university professor at Columbia. Dr. Hendrickson is a university professor at Columbia University in the department of biochemistry and molecular biophysics and Violin Family Professor of Physiology and Cellular Biophysics. He is also Chief Life Scientist in the Photon Sciences Directorate at Brookhaven National Laboratory and scientific director of the New York Structural Biology Center. Hendrickson has a B.A. from the University of Wisconsin at River Falls, a Ph.D. in biophysics at Johns Hopkins University with Warner Love, and postdoctoral research experience with Jerome Karle at the Naval Research Laboratory (NRL). He and his colleagues use biochemistry and x-ray crystallography to study molecular properties in atomic detail with current emphasis on membrane receptors and cellular signaling, on viral proteins and HIV infection, on molecular chaperones and protein folding, and on structural genomics of membrane proteins. Hendrickson's advances in diffraction methodology have contributed significantly to the emergence of structural biology as a major force in modern biology and molecular medicine.
Sheena Elizabeth Radford is a British biophysicist, and Astbury Professor of Biophysics and a Royal Society Research Professor in the Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology at the University of Leeds. Radford is the Associate Editor of the Journal of Molecular Biology.
John E. Dowling is an American neuroscientist and Gordon and Llura Gund Research Professor of Neurosciences at Harvard University. He is best known for his seminal work in vision science, having elucidated the biochemistry of rhodopsin and development of the vertebrate retina, as well as diseases that affect vision such as vitamin A deficiency and retinitis pigmentosa. He was elected to the American Academy of Arts and Sciences in 1972, the National Academy of Sciences in 1976, and the American Philosophical Society in 1992.
Hao Wu is a Chinese American biochemist and crystallographer and the Asa and Patricia Springer Professor of Structural Biology in the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. Her work focuses on molecular mechanisms of signal transduction in cell death and inflammation. She is the discoverer of signalosomes, which are large macromolecular complexes involved in cell death and in innate and adaptive immune pathways. She has established a new paradigm for signal transduction that involves higher-order protein assemblies. She has received the Pew Scholar Award, the Rita Allen Scholar Award, the Margaret Dayhoff Memorial Award, the NYC Mayor's Award for Excellence in Science and Technology, NIH MERIT and Pioneer Awards, and the Purdue University Distinguished Science Alumni Award. She was elected AAAS fellow in 2013 and to the National Academy of Sciences in 2015.
Jue Chen is a Chinese-born American structural biologist and biochemist. She is the William E. Ford professor of biochemistry and head of the Laboratory of Membrane Biology and Biophysics at the Rockefeller University and a Howard Hughes Medical Institute investigator. Her research focuses on elucidating the structure and function of ATP-binding cassette (ABC) transporters.
Sabine Kastner is a German-born American cognitive neuroscientist. She is professor of psychology at the Princeton Neuroscience Institute at Princeton University. She also holds a visiting scientist appointment at the University of California at Berkeley.
Wolfgang P. Baumeister is a German molecular biologist and biophysicist. His research has been pivotal in the development of Cryoelectron tomography.
Bonnie Ann Wallace, FRSC is a British and American biophysicist and biochemist. She is a professor of molecular biophysics in the department of biological sciences, formerly the department of crystallography, at Birkbeck College, University of London, U.K.
Floris de Lange is a cognitive neuroscientist known for his contributions in the fields of perception research, and predictive coding using laminar fMRI, magnetoencephalography, computational modeling, and AI models for neuroscience. Currently, de Lange holds the position of Principal Investigator at the Donders Center for Cognitive Neuroimaging, where he established the Predictive Brain Lab. Additionally, he serves as a senior editor at eLife and he is professor of Perception and Cognition at the Faculty of Social Sciences of the Radboud University Nijmegen.