Jacques Cohen (embryologist)

Last updated
Jacques Cohen
Born (1951-12-26) 26 December 1951 (age 73)
The Hague, Netherlands
Nationality Flag of the Netherlands.svg Dutch
Alma mater Erasmus University
State University of Leiden
Known for reproductive medicine
in-vitro fertilization
cryopreservation
Scientific career
FieldsEmbryology
Institutions University of Cambridge
Cornell University
Reprogenetics
Althea

Jacques Cohen (born December 26, 1951) is a Dutch embryologist based in New York. He is a Director at Reprogenetics LLC, [1] [2] Laboratory Director at ART Institute of Washington at Walter Reed National Military Medical Center [3] (a joint fertility program with NIH), and Scientific Director of R & D at IVF-online.[ citation needed ]

Contents

While working with Robert G. Edwards at Bourn Hall Clinic, Cambridge, Cohen reported results in the freezing and successful thawing of a human blastocyst for in vitro fertilization. [4] At the same clinic, he developed methods to treat male factor infertility using in vitro fertilization (IVF) and co-cultured human embryos with helper cells to promote growth. [5]

Cohen has been involved in research on the application of micromanipulation techniques to operate on eggs, sperm and embryos. He has (co-)published papers on Intracytoplasmic Sperm Injection (ICSI) [6] and Assisted Hatching. [7]

As of October 2024, he is listed as an Emeritus Chief Editor at Reproductive Biomedicine Online. [8] He has also held faculty positions at Emory University, Cornell University Medical College, and the University of Connecticut.[ citation needed ]

Early career and education

Cohen was born in The Hague, Netherlands. In 1970, he went to the State University of Leiden, where he received a BSc degree in Biochemistry and subsequently an MSc degree in Reproductive physiology in 1978. [9] He attended the Erasmus University Rotterdam, where he obtained a PhD degree in Medicine in 1982, for his thesis "Interaction between human spermatozoa and hamster oocytes". [10]

Embryology

In 1982, Cohen joined Bourn Hall Clinic as an embryologist, working with Patrick Steptoe and Robert G. Edwards on techniques to improve human conception through in vitro fertilization (IVF). Robert G. Edwards was the recipient of the Nobel Prize for Medicine and Physiology in 2010. It was in Cambridge that Cohen first successfully froze and thawed a human blastocyst for use in IVF. [11] Cohen also pioneered the use of micromanipulation techniques now widespread among embryologists. He developed a precursor technique of Intracytoplasmic Sperm Injection (ICSI), now used for the treatment of nearly all male factor infertility diagnoses. Assisted Hatching (AH) is another commonly applied technique aimed at increasing implantation rates among infertile couples. Some of his work, such as cytoplasmic transfer, an attempt to boost development using the cytoplasm of donor eggs to supplement eggs from certain infertility patients, and single sperm freezing, has caused considerable ethical debate. [12]

References

  1. ↑ Reprogenetics Meet Our Team.
  2. ↑ IVF.NET "Jacques Cohen - Embryo Selection" IVF.NET , 31 May 2009.
  3. ↑ ART Institute of Washington - About Us Archived 2012-04-25 at the Wayback Machine Jacques Cohen.
  4. ↑ Cohen, Jacques; Simons, Roger F.; Edwards, Robert G.; Fehilly, Carole B.; Fishel, Simon B. (1985). "Pregnancies following the frozen storage of expanding human blastocysts". Journal of in Vitro Fertilization and Embryo Transfer. 2 (2): 59–64. doi:10.1007/BF01139337. PMID   4020239. S2CID   8187851.[ non-primary source needed ]
  5. ↑ Lai, YM; Stein, DE; Soong, YK; Tang, YX; Grifo, J; Malter, HE; Talansky, BE; Cohen, J; et al. (1992). "Evaluation of Vero cell co-culture system for mouse embryos in various media". Human Reproduction. 7 (2): 276–80. doi:10.1093/oxfordjournals.humrep.a137632. PMID   1577944.[ non-primary source needed ]
  6. ↑ Palermo, GD; Cohen, J; Alikani, M; Adler, A; Rosenwaks, Z (1995). "Intracytoplasmic sperm injection: A novel treatment for all forms of male factor infertility". Fertility and Sterility. 63 (6): 1231–40. doi: 10.1016/S0015-0282(16)57603-1 . PMID   7750593.[ non-primary source needed ]
  7. ↑ Cohen, Jacques (1991). "Assisted hatching of human embryos". Journal of in Vitro Fertilization and Embryo Transfer. 8 (4): 179–90. doi:10.1007/BF01130802. PMID   1753162. S2CID   22604458.[ non-primary source needed ]
  8. ↑ Reproductive Biomedicine Online Journal Info - Editorial Board
  9. ↑ Jacques Cohen, Ph.D - website bestivf.org
  10. ↑ Doctoral dissertation J. Cohen (Jacques): Interactie tussen menselijke zaadcellen en hamstereicellen - website of Erasmus University Rotterdam's institutional repository, RePub
  11. ↑ Cohen, Jacques; Simons, Roger F.; Edwards, Robert G.; Fehilly, Carole B.; Fishel, Simon B. (1985-06-01). "Pregnancies following the frozen storage of expanding human blastocysts". Journal of in Vitro Fertilization and Embryo Transfer. 2 (2): 59–64. doi:10.1007/BF01139337. ISSN   1573-7330. PMID   4020239. S2CID   8187851.
  12. ↑ Barritt, J. A.; Willadsen, S.; Brenner, C.; Cohen, J. (2001). "Cytoplasmic transfer in assisted reproduction". Human Reproduction Update. 7 (4): 428–35. doi: 10.1093/humupd/7.4.428 . PMID   11476356.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.