Jane A. McKeating

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Professor Jane A. McKeating
NationalityBritish
Alma mater University of Warwick
University College London
Known forDeputy Head of School of Immunity and Infection (University of Birmingham)
Scientific career
Fields Molecular virology, Microbiology
Institutions University of Birmingham
Website www.birmingham.ac.uk/staff/profiles/iandi/mckeating-jane.aspx

Jane A. McKeating is a professor of molecular biology at Oxford University, and honorary professor at the University of Birmingham, England, where she worked as a professor of molecular virology until 2017. [1] She is listed as a notable scientist in Thomson Reuters' Highly Cited Researchers 2014, ranking her among the top 1% most cited scientists. [2]

Contents

Education

McKeating obtained a Bachelor of Science degree (BSc, Hons) from the University of Warwick in 1982 and a Doctorate from University College London in 1987. [3]

Career

McKeating was a fellow of the Lister Institute of Preventive Medicine from 1994 to 1999. [4]

In 2005, McKeating became professor of molecular virology and deputy head of the School of Immunity and Infection at the University of Birmingham, where she established the school's HCV group which is involved in various national and international collaborative studies.

In 2017, she was appointed as professor of molecular biology at Oxford University, and continues as an honorary professor of the University of Birmingham. [1] In 2019 she became an official fellow of Parks College. [5]

McKeating is a member of the scientific advisory boards for the University of Essen, Astex Pharmaceuticals, and Arrow Pharmaceuticals. [6]

Research areas

McKeating's research focuses on the molecular biology of hepatitis B (HBV) and hepatitis C (HCV), particularly the role of cell surface receptors in the viral life cycle [7] and the role of hypoxia in viral infection [8] [9] [10] [11] .

Selected publications

References

  1. 1 2 "University of Oxford Medical Sciences Division" . Retrieved 18 February 2018.
  2. ↑ "Highly Cited Researchers 2014". highlycited.com. Retrieved 16 April 2015.
  3. ↑ "Jane A. McKeating". Technical University of Munich . Retrieved 31 May 2023.
  4. ↑ "Former Fellows". lister-institute.org.uk. Retrieved 17 April 2015.
  5. ↑ "Parks College People". University of Oxford. Retrieved 29 November 2019.
  6. ↑ "University of Birmingham, Viral Hepatitis Research – Jane McKeating". Archived from the original on 28 December 2014. Retrieved 6 April 2015.
  7. ↑ "Stop-HCV, Stratified Medicine for HepC – Jane McKeating" . Retrieved 6 April 2015.
  8. ↑ Wing, Peter A.C.; Liu, Peter Jianrui; Harris, James M.; Magri, Andrea; Michler, Thomas; Zhuang, Xiaodong; Borrmann, Helene; Minisini, Rosalba; Frampton, Nicholas R.; Wettengel, Jochen M.; Mailly, Laurent; D’Arienzo, Valentina; Riedl, Tobias; Nobre, Luis; Weekes, Michael P. (July 2021). "Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter". Journal of Hepatology. 75 (1): 64–73. doi:10.1016/j.jhep.2020.12.034. PMC   8214165 . PMID   33516779.
  9. ↑ Wing, Peter A.C.; Keeley, Thomas P.; Zhuang, Xiaodong; Lee, Jeffrey Y.; Prange-Barczynska, Maria; Tsukuda, Senko; Morgan, Sophie B.; Harding, Adam C.; Argles, Isobel L.A.; Kurlekar, Samvid; Noerenberg, Marko; Thompson, Craig P.; Huang, Kuan-Ying A.; Balfe, Peter; Watashi, Koichi (April 2021). "Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells". Cell Reports. 35 (3): 109020. doi:10.1016/j.celrep.2021.109020. PMC   8020087 . PMID   33852916.
  10. ↑ Schilling, Mirjam; Vaughan-Jackson, Alun; James, William; McKeating, Jane A. (16 August 2023). "Hypoxia dampens innate immune signalling at early time points and increases Zika virus RNA levels in iPSC-derived macrophages". Journal of General Virology. 104 (8). doi:10.1099/jgv.0.001885. ISSN   0022-1317. PMC   10877081 . PMID   37584553.
  11. ↑ Zhuang, Xiaodong; Gallo, Giulia; Sharma, Parul; Ha, Jiyeon; Magri, Andrea; Borrmann, Helene; Harris, James M.; Tsukuda, Senko; Bentley, Eleanor; Kirby, Adam; de Neck, Simon; Yang, Hongbing; Balfe, Peter; Wing, Peter A.C.; Matthews, David (January 2024). "Hypoxia inducible factors inhibit respiratory syncytial virus infection by modulation of nucleolin expression". iScience. 27 (1): 108763. Bibcode:2024iSci...27j8763Z. doi:10.1016/j.isci.2023.108763. PMC   10797196 . PMID   38261926.
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