Jane Stewart (scientist)

Jane Stewart
Alma mater	Queen's University, University of London
Scientific career
Fields	Behavioral neuroscience
Institutions	Concordia University

Jane Stewart OC FRSC is a Canadian neuroscientist who has been active in the fields of psychology, psychiatry, and psychopharmacology. She is a professor emerita at Concordia University in Montreal, Canada.

Career

Stewart earned a Bachelor of Arts degree in psychology and biology from Queen's University in 1956, and PhD in psychology in 1959 from the University of London, England. ^{[1] [2]} She then started working for Ayerst Pharmaceuticals in Montreal and subsequently joined Concordia University in 1962, ^[3] where she served as chair of the Department of Psychology (1969–1974) and director of the Center for Studies in Behavioral Neurobiology (1990–1997). ^[1] She served on many grant review committees and on the editorial boards of 11 peer-reviewed scientific journals. ^[1]

Research

Stewart has made seminal contributions to different areas of research, such as conditioned drug effects, ^{[4] [5]} the motivational effects of drugs, ^[6] circadian rhythms, ^[7] antidepressant and antipsychotic drug action, ^{[8] [9]} and sexual behavior. ^{[10] [11]}

Honors

Stewart was awarded an honorary degree from Queen's University and is a Fellow of the American Association for the Advancement of Science, the American Psychological Association, the Canadian Psychological Association, and the Royal Society of Canada. ^[1] She also received the highest civilian honor in her country, being appointed Officer in the Order of Canada in 2007. ^[1] A special issue of the journal Biological Psychiatry was dedicated to her on the occasion of her retirement in 2008. ^[1]

Significant papers

• Kalivas PW, Stewart J (1991). "Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity". Brain Research Reviews . 16 (3): 223–44. doi:10.1016/0165-0173(91)90007-U. PMID   1665095. S2CID   10775295. (cited over 1300 times) ^[12]
• Stewart J, de Wit H, Eikelboom R (April 1984). "Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants". Psychological Review . 91 (2): 251–68. doi:10.1037/0033-295X.91.2.251. PMID   6571424. (cited over 600 times) ^[12]
• de Wit H, Stewart J (1981). "Reinstatement of cocaine-reinforced responding in the rat" (PDF). Psychopharmacology . 75 (2): 134–43. doi:10.1007/BF00432175. PMID   6798603. S2CID   2627859. (cited over 400 times) ^[12]
• Stewart J, Badiani A (1993). "Tolerance and sensitization to the behavioral effects of drugs". Behavioural Pharmacology . 4 (4): 289–312. doi:10.1097/00008877-199308000-00003. PMID   11224198. (cited over 350 times) ^[12]
• Shaham Y, Shalev U, Lu L, De Wit H, Stewart J (July 2003). "The reinstatement model of drug relapse: history, methodology and major findings". Psychopharmacology. 168 (1–2): 3–20. doi:10.1007/s00213-002-1224-x. PMID   12402102. S2CID   144348217. (cited over 300 times) ^[12]

References

1. de Wit H, Shaham Y (May 2009). "Incentive motivation, conditioning, stress, and neuropsychiatric disorders: A tribute to Jane Stewart". Biological Psychiatry. 65 (10): 827–8. doi:10.1016/j.biopsych.2008.12.012. PMC   2716031 . PMID   19398047.
2. "Jane Stewart CV" (PDF). Concordia University. 2015. Retrieved 2019-12-13.
3. "Jane Stewart". www.concordia.ca. Archived from the original on 2016-03-10. Retrieved 2016-03-09.
4. Eikelboom R, Stewart J (September 1982). "Conditioning of drug-induced physiological responses". Psychological Review . 89 (5): 507–28. doi:10.1037/0033-295X.89.5.507. PMID   7178331.
5. Stewart J (June 1992). "Neurobiology of conditioning to drugs of abuse". Annals of the New York Academy of Sciences . 654 (1): 335–46. Bibcode:1992NYASA.654..335S. doi:10.1111/j.1749-6632.1992.tb25979.x. PMID   1321575. S2CID   29924902.
6. Stewart J, de Wit H, Eikelboom R (April 1984). "Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants". Psychological Review. 91 (2): 251–68. doi:10.1037/0033-295X.91.2.251. PMID   6571424.
7. Amir S, Stewart J (February 1996). "Resetting of the circadian clock by a conditioned stimulus". Nature . 379 (6565): 542–5. Bibcode:1996Natur.379..542A. doi:10.1038/379542a0. PMID   8596633. S2CID   4325922.
8. Stewart J, Rajabi H (August 1996). "Initial increases in extracellular dopamine in the ventral tegmental area provide a mechanism for the development of desipramine-induced sensitization within the midbrain dopamine system". Synapse . 23 (4): 258–64. doi:10.1002/(SICI)1098-2396(199608)23:4<258::AID-SYN3>3.0.CO;2-6. PMID   8855510. S2CID   37789995.
9. Samaha AN, Seeman P, Stewart J, Rajabi H, Kapur S (March 2007). ""Breakthrough" dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time". Journal of Neuroscience . 27 (11): 2979–86. doi:10.1523/JNEUROSCI.5416-06.2007. PMC   6672560 . PMID   17360921.
10. Mitchell JB, Stewart J (March 1990). "Facilitation of sexual behaviors in the male rat associated with intra-VTA injections of opiates". Pharmacology Biochemistry and Behavior . 35 (3): 643–50. doi:10.1016/0091-3057(90)90302-X. PMID   1971113. S2CID   45442957.
11. Mitchell JB, Stewart J (February 1990). "Facilitation of sexual behaviors in the male rat in the presence of stimuli previously paired with systemic injections of morphine". Pharmacology Biochemistry and Behavior. 35 (2): 367–72. doi:10.1016/0091-3057(90)90171-D. PMID   2320644. S2CID   6336713.
12. Web of Science, accessed May 6, 2009