Professor Jean Golding OBE, FMedSci | |
---|---|
Born | 22 September 1939 |
Occupation | Epidemiologist |
Known for | Avon Longitudinal Study of Parents and Children (ALSPAC) |
Jean Golding OBE , FMedSci, (born Jean Bond 22 September 1939, also known as Jean Fedrick between 1962 and 1977) [1] is a British epidemiologist, and founder of the Avon Longitudinal Study of Parents and Children (ALSPAC), also known as "Children of the Nineties". She is Emeritus Professor of Paediatric and Perinatal Epidemiology at the University of Bristol.
Born in Hayle, Cornwall in 1939, Golding struggled with illness throughout her childhood. Her regular stays in hospital led to a delay in the beginning of her education, eventually starting school when she was six years old. Her family moved to Chester, after a period living in Plymouth, and within a few weeks she contracted polio, causing her to miss another year of school and causing a disability that would remain with her permanently. Despite these interruptions to her schooling, she won a place studying mathematics at St Anne's College, Oxford in 1958, [2] from where she was awarded an honours BA, and subsequently MA.
In 1966 she joined a team in London, headed by Neville Butler and Eva Alberman, [3] analysing data collected in the 1958 Perinatal Mortality Survey (later the 1958 birth cohort) British birth cohort studies. She then obtained a research fellowship in the Galton Laboratory of Human Genetics and Biometry, University College London Galton Laboratory to study the aetiology of neural tube defects. Subsequent research at the University of Oxford, involved working with large data sets including the Oxford Record Linkage Study.
In 1980 she moved to the University of Bristol, where she was involved in analysing data from the national 1970 birth cohort British birth cohort studies. During the 1980s she was responsible for assisting in designing and augmenting a major perinatal survey in Jamaica 1985-6, [4] and developed, and was the initial Director of the European Longitudinal Study of Pregnancy and Childhood (ELSPAC). [5] This led to the founding of ALSPAC (Avon Longitudinal Study of Parents and Children), also known as Children of the 90s, a birth cohort study, the overall aim of which is to determine the ways in which different aspects of the environment influence child health and development, and how these may be influenced by genetics. [6] The study has resulted in a highly detailed dataset of children born in the Avon area in 1991 and 1992, their parents and, as time has gone on, their own children. It continues to record biological, psychological, social and medical information of these groups throughout their childhoods and into their adult lives ALSPAC. The dataset is used by researchers across the world, [2] and it includes interviews, questionnaires, biological samples, hands-on testing and linkage to educational and other records. Data collection has continued since the children were born. Golding's decision on what data was useful to collect has led to it being used for genetic and Epigenetics research worldwide, [7] and, by 2019, around 2000 peer-reviewed papers based on this resource have been published.
In 1987 she was the founding editor of the international journal: Paediatric and Perinatal Epidemiology and continued as editor-in-chief until 2012. [8] Golding has continued to carry out research on the ALSPAC resource long into retirement, and has concentrated since 2016 on the following: i) Ways in which the aspect of personality known as Locus of Control of the parents and children influences behaviours, and long term outcomes (with Stephen Nowicki, at Emory University), ii) Ways in which environmental exposures to grandparents and great-grandparents are associated with outcomes in grandchildren and great-grandchildren, including of autism, and obesity (with Marcus Pembrey and Matthew Suderman). iii) Long-term outcomes of offspring relating to various exposures of the mother including medications (such as paracetamol/acetaminophen), heavy metals (especially mercury) and aspects of the diet (especially the benefits of fish consumption) iv) The question as to whether religious and/or spiritual beliefs affect behaviours and how that might impact health and development.
In 2012 she was made an Officer of the Order of the British Empire for services to medical science. [2] [9]
In 2013, she received an honorary Doctor of Laws degree from the University of Bristol, acclaimed as an "exemplar of the qualities and values the institution promotes". [10]
In 2016, the University of Bristol created the Jean Golding Institute, a multidisciplinary data science and data-intensive research hub, in honour of her work as a mathematician, epidemiologist and founder of the Children of the 90s cohort study. [11]
In 2017, she received an honorary Doctor of Science from University College London for her pioneering work on longitudinal population studies. [12]
In 2018, as a celebration of the 70 years since the start of the NHS, she was made one of seven "NHS Research Legends". [13]
In 2018, the University of Bristol honoured its pioneering women in suffrage centenary portraits, which were unveiled as part of the 'Women and equality: the next 100 years' event. Kate Robson Brown, the Director of the Jean Golding Institute, holding a portrait of Jean Golding OBE. [14]
Again in 2018, in response to a national call by English Heritage Put her Forward campaign (in response to the realisation of the paucity of statues of women in Britain), Golding was nominated, and among 25 women to have a 3-D printed statuette. [15] [16] This is currently displayed in the Royal Fort House at the University of Bristol.
In 2022, she was elected a member of the Academia Europaea. [17]
On 18 November 2022, she was the guest of an episode of Desert Island Discs . [18]
Marcus Edred Pembrey FMedSci is a British clinical geneticist with a research interest in non-Mendelian inheritance in humans. He is Emeritus Professor of Paediatric Genetics at UCL Great Ormond Street Institute of Child Health and Visiting Professor of Paediatric Genetics, University of Bristol. He featured in a 2005 'Horizon' program on BBC television called 'the Ghost in Your Genes'.
ESDS Longitudinal is a specialist service of the Economic and Social Data Service (ESDS), led by the UK Data Archive at the University of Essex and the ESRC United Kingdom Longitudinal Studies Centre (ULSC), jointly funded by the Joint Information Systems Committee (JISC) and the Economic and Social Research Council (ESRC).
The National Child Development Study (NCDS) is a continuing, multi-disciplinary longitudinal study which follows the lives of 17,415 people born in England, Scotland and Wales from 17,205 women during the week of 3–9 March 1958. The results from this study helped reduce infant mortality and were instrumental in improving maternity services in the UK.
Birth cohort studies in Britain are four long-term medical and social studies, carried out over the lives of a group of participants, from birth. The earliest two started in 1946 and 1958.
The Avon Longitudinal Study of Parents and Children (ALSPAC), also known as Children of the 90s and formerly the Avon Longitudinal Study of Pregnancy and Childhood, is a cohort study of children born in the former county of Avon, England during 1991 and 1992. It is used by researchers in health, education and other social science disciplines.
Irva Hertz-Picciotto, is an environmental epidemiologist best known for her studies of autism. She is Professor and Chief of the Division of Environmental and Occupational Health in the Department of Public Health Sciences, at the University of California, Davis (UC-Davis). In addition, she is on the Research Faculty of the MIND Institute at UC-Davis; the Deputy Director of the UC-Davis Center for Children's Environmental Health; and on the faculty of the Center for Occupational and Environmental Health of the Universities of California at Berkeley, Davis, and San Francisco. Hertz-Picciotto serves on the advisory board of the anti-toxic chemical NGO Healthy Child, Healthy World.
Catherine S. Peckham FFPHM is a British paediatrician.
Heather Evelyn Joshi, is a British academic, economist, and demographer. She is Emeritus Professor of Economic and Developmental Demography at the University of London. She was Director of the Centre for Longitudinal Studies from 2003 to 2010.
Generation R is a prospective, population based cohort study from fetal life until young adulthood in a multi-ethnic urban population in Rotterdam, the Netherlands. The study is designed to identify early environmental and genetic causes of normal and abnormal growth, development and health. Eventually, results forthcoming from the Generation R Study have to contribute to the development of strategies for optimizing health and healthcare for pregnant women and children.
George Davey Smith is a British epidemiologist. He has been professor of clinical epidemiology at the University of Bristol since 1994, honorary professor of public health at the University of Glasgow since 1996, and visiting professor at the London School of Hygiene and Tropical Medicine since 1999.
The Raine Study is one of the largest prospective cohort studies of pregnancy, childhood, adolescence and now early adulthood to be carried out anywhere in the world. Its purpose is to improve human health and well-being, through the study of a cohort of Western Australians from before birth onwards.
Emma Fransson is a child psychologist and epidemiologist at Stockholm University and the Karolinska Institute in Sweden. Her expertise is in the health and social implication of shared parenting arrangements on children after their parents are divorced. She has also studied the effects of stress during pregnancy.
Kate Tilling is a British statistician who specialises in developing and applying statistical methods to overcome problems encountered in epidemiological research. Tilling has been a professor in medical statistics. in population health sciences within Bristol Medical School, University of Bristol, since 2011. She joined the University of Bristol in 2002 as a Senior Lecturer, following nine years as a lecturer at King's College London.
The Collaborative Perinatal Project, also known as the National Collaborative Perinatal Project, was a multisite prospective cohort study designed to identify the effects of complications during either pregnancy or the perinatal period on birth and child outcomes, especially neurological disorders such as cerebral palsy. It was conducted by the National Institute of Neurological and Communicative Disorders and Stroke on over 55,000 pregnant mothers at 12 sites across the United States from 1959 to 1965. It is one of the largest and broadest epidemiological studies in American history; according to Mark Klebanoff, "No U.S.-based study of pregnancy and childhood conducted before or since has matched its size, breadth and depth".
Dieter Wolke is Professor of Developmental Psychology and Individual Differences at the University of Warwick, Department of Psychology, and at the Division of Health Sciences at Warwick Medical School since 2006. In 2020, he was named by the British Psychological Society for Distinguished Contributions to British Developmental Psychology award. He has also been named as a highly cited researcher, ranking in the top 1% of citations in Web of Science by Clarivate every year since 2018.
Alan M. Emond is a British paediatrician and professor emeritus in Child Health at Bristol Medical School at the University of Bristol. Emond is most notable for research into child and adolescent injury, epidemiology and health service evaluation as well as the Avon Longitudinal Study of Parents and Children.
Alison Ellen Field is an American epidemiologist. Field currently serves as professor and chair of epidemiology at the Brown University School of Public Health and professor of pediatrics at Brown's Alpert Medical School.
Mia Lilly Kellmer Pringle was an Austrian-British child psychologist. She was the founding director of the British National Children's Bureau, where she oversaw the influential National Child Development Study. Over the course of her career, Pringle advocated for the needs and rights of children both through her research-informed policy work and in her many books and articles about early childhood development.
Susan Mary Bennett Morton is a New Zealand epidemiologist, and is a full professor of public health at the University of Technology Sydney, specialising in longitudinal studies of public health. In 2019, Morton was appointed a Member of the New Zealand Order of Merit for services to epidemiology and public health research.
Diana Jane Lewin Kuh is a British epidemiologist who is an emeritus professor of Life Course Epidemiology at University College London. She was formerly Scientific Director of the National Survey of Health and Development. Kuh has been consistently named one of the most cited women scientists in the world.