Jeffrey Hubbell | |
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Thesis | Visualization and Analysis of Mural Thrombogenesis (Platelet Adhesion, Collagen, Polyurethane, Digital Image Processing) (1986) |
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Jeffrey Alan Hubbell is an American bioengineering working immunoengineering. His research has focused on topics from physical biology,biomaterials,regenerative medicine,and translational immunology.
He received his bachelor's degree from Kansas State University and his PhD from Rice University,both in chemical engineering. [1] His doctoral mentor was Larry V. McIntire,in a project addressing the biophysics of thrombosis. [2]
Upon completing his PhD,Hubbell joined the Chemical Engineering Department at the University of Texas. In 1995,he moved to the Division of Chemistry and Chemical Engineering at Caltech,and then in 1997 to the Institute of Biomedical Engineering at ETH Zurich and the University of Zurich.
In 2003 Hubbell joined the faculty at Switzerland's École Polytechnique Fédérale de Lausanne (EPFL) where he served as the founding director of the Institute of Bioengineering. [3] Hubbell remained in Switzerland until 2014 when he accepted a position at the University of Chicago faculty of the Pritzker School of Molecular Engineering as their Barry L. MacLean Professor for Molecular Engineering Innovation and Enterprise. [3] By 2017,Hubbell was the recipient of the Society for Biomaterials’Founders Award for his "long-term,landmark contributions to the discipline of biomaterials." He was specifically recognized for designing materials to assemble and function so they could stimulate the immune system to fight infection or malignancy and coining the term "immuno-modulatory materials." [4] In the same year,Hubbell was awarded the Acta Biomaterialia Gold Medal [5] and appointed the inaugural Bell Professor in Tissue Engineering at the University of Chicago. [6]
In 1995,Hubbell was elected a fellow of the American Institute for Medical and Biological Engineering for his "fundamental and clinically-applied contributions to biomaterials." [7] In 2010,he was elected to the National Academy of Engineering “for contributions to the science,engineering,and technology of bioactive materials for the benefit of patients.” [8] Upon joining the University of Chicago,Hubbell collaborated with Cathryn Nagler to establish the ClostraBio,a company to develop drugs. [9] In 2018,Hubbell was also elected a Member of the National Academy of Medicine for his work "pioneering the development of cell responsive (bioactive) materials and inventing biomaterials that are now widely utilized in regenerative medicine." [10] Following this,he helped develop a vaccine platform for infectious disease. [11] In 2021,Hubbell was one of eight University of Chicago faculty members elected to the American Academy of Arts and Sciences. [12] In 2023,he as elected to the third national academy,the National Academy of Sciences. [13] [14] He was also elected a fellow of the National Academy of Inventors. [15]
As to recent research,in 2019 [16] and 2023, [17] Hubbell and colleagues,including D. Scott Wilson, [18] published an approach to inverse vaccination,with implications for treatment of autoimmunity. In April 2020,Hubbell,Melody Swartz,and Jun Ishihara [19] co-published their research on an immunotherapy delivery system that finds tumors by seeking out and binding to the tumors’collagen. [20] Following this development,he helped design a new therapy to eventually assist those with autoimmune diseases by fusing a tolerogenic cytokine to a blood protein that accumulates in the lymph nodes. [21]
Effective November 15th,2024,Hubbell was appointed as professor of chemical and biomolecular engineering in the Grossman School of Medicine at NYU,leading a cross-institutional initiative with NYU Langone while also serving as Vice President for bioengineering strategy. [22] The aim of this cross-institutional initiative expects to develop a "strong immune-engineering focus,including:autoimmunity,inflammatory disease,allergy,transplantation,neurodegeneration,cardiometabolic disease,tissue repair,cancer immunotherapy,vaccination,and infectious disease." [22]
Tejal Ashwin Desai is Sorensen Family Dean of Engineering at Brown University. Prior to joining Brown,she was the Deborah Cowan Endowed Professor in the Department of Bioengineering and Therapeutic Sciences at University of California,San Francisco,Director of the Health Innovations via Engineering Initiative (HIVE),and head of the Therapeutic Micro and Nanotechnology Laboratory. She was formerly an associate professor at Boston University (2002–06) and an assistant professor at University of Illinois at Chicago (1998–2001). She is a researcher in the area of therapeutic micro and nanotechnology and has authored and edited at least one book on the subject and another on biomaterials.
Linda Gay Griffith is an American biological engineer,and Professor of Biological Engineering and Mechanical Engineering at Massachusetts Institute of Technology,where she also directs the Center for Gynepathology Research.
Kristi S. Anseth is the Tisone Distinguished Professor of Chemical and Biological Engineering,an Associate Professor of Surgery,and a Howard Hughes Medical Investigator at the University of Colorado at Boulder. Her main research interests are the design of synthetic biomaterials using hydrogels,tissue engineering,and regenerative medicine.
David James Mooney is Robert P. Pinkas Family Professor of Bioengineering at the Harvard School of Engineering and Applied Sciences. He is also a founding core faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard University.
Gordana Vunjak-NovakovicFRSC is a Serbian American biomedical engineer and university professor. She is a University Professor at Columbia University,as well as the Mikati Foundation Professor of Biomedical Engineering and Medical Sciences. She also heads the laboratory for Stem Cells and Tissue Engineering at Columbia University. She is part of the faculty at the Irving Comprehensive Cancer Center and the Center for Human Development,both found at Columbia University. She is also an honorary professor at the Faculty of Technology and Metallurgy at the University of Belgrade,an honorary professor at the University of Novi Sad,and an adjunct professor at the Department of Biomedical Engineering at Tufts University.
Samir Mitragotri is an Indian American professor at Harvard University,an inventor,an entrepreneur,and a researcher in the fields of drug delivery and biomaterials. He is currently the Hiller Professor of Bioengineering and Hansjörg Wyss Professor of Biologically Inspired Engineering at Harvard John A. Paulson School of Engineering and Applied Sciences and the Wyss Institute for Biologically Inspired Engineering. Prior to 2017,he was the Duncan and Suzanne Mellichamp Chair Professor at University of California,Santa Barbara.
Buddy Ratner is an American professor of chemical engineering and bioengineering. He is the director of the Research Center for Biomaterials at the University of Washington. He is also the faculty member for the Program for Technology Commercialization at the University of Washington.
Melody A. Swartz is a professor and vice dean for faculty affairs at the University of Chicago who pioneered research in engineering complex tissues. Her most cited work "Capturing complex 3D tissue physiology in vitro" has been cited over 1784 times. Her research is focused on understanding the role of the lymphatic system regulating immunity in homeostasis and diseases,particularly cancer. She was previously director of the Institute of Bioengineering at the École Polytechnique Fédérale de Lausanne. She was elected to the National Academy of Engineering in 2023,the Royal Academy of Medicine of Belgium in 2023,and the National Academy of Medicine in 2020.
Song Li is a Chancellor Professor and Department Chair of Bioengineering at University of California,Los Angeles. He received his Ph.D. in bioengineering from University of California,San Diego. Dr. Li was a Bioengineering faculty at University of California,Berkeley (2001-2015),and he moved to UCLA in 2016. His research is focused on cell engineering,mechanobiology,biomaterials,and regenerative medicine. He is well recognized bioengineer,and has been elected as a Fellow of the International Academy of Medical and Biological Engineering,Biomedical Engineering Society and American Institute for Medical and Biological Engineering.
The Institute for Bioengineering of Catalonia (IBEC) is an institution engaged in basic and applied research in bioengineering and nanomedicine,with experts working on tissue regeneration,biomechanics,molecular dynamics,biomimetics,drug delivery,organs ‘on-a-chip’,cell migration,stem cells,artificial olfaction and microbial biotechnology. The institute was created by the Government of Catalonia,the University of Barcelona and the Polytechnic University of Catalonia in December 2005 and is located at the Barcelona Science Park. The director of the institute is Prof. Josep Samitier,who took over from founding director Josep A. Planell i Estany in 2013. In 2014 IBEC was named a "Severo Ochoa Centre of Excellence" by the Spanish Ministry of Economy and Competitiveness.
Maryellen L. Giger, is an American physicist who has made significant contributions to the field of medical imaging.
Jennifer Hartt Elisseeff is an American biomedical engineer,ophthalmologist and academic. She is the Morton Goldberg Professor and Director of the Translational Tissue Engineering Center at Johns Hopkins Department of Biomedical Engineering and the Wilmer Eye Institute with appointments in Chemical Engineering,Biomedical Engineering,Materials Science and Orthopedic Surgery. Elisseeff's research is in the fields of regenerative medicine and immunoengineering.
Laura Elizabeth Niklason is a physician,professor and internationally recognized researcher in vascular and lung tissue engineering. She is the Nicholas M. Greene Professor of Anesthesiology and Biomedical Engineering at Yale University and co-founder,chief executive officer and president of Humacyte,a regenerative medicine company developing bioengineered human tissues.
Matthias Lutolf is a bio-engineer and a professor at EPFL where he leads the Laboratory of Stem Cell Bioengineering. He is specialised in biomaterials,and in combining stem cell biology and engineering to develop improved organoid models. In 2021,he became the scientific director for Roche's Institute for Translation Bioengineering in Basel.
Adekunle O. Odunsi is an American gynecologic oncologist. In 2021,Odunsi became the director of the University of Chicago Comprehensive Cancer Center.
Helen Haiyan Lu is a Chinese American biomedical engineer and the Percy K. and Vida L. W. Hudson professor of biomedical engineering at the Columbia University Fu Foundation School of Engineering and Applied Science. Her work focuses on understanding and developing therapies in complex tissue systems,especially the interface between soft tissue and bone.
Kiana Aran is a biomedical entrepreneur and Associate Professor at both UC San Diego's School of Medicine and UC San Diego's Jacobs School of Engineering in the Department of Bioengineering. She is also the Chief Innovation Officer at Paragraf Ltd. Paragraf,a UK-based semi-conductor company,acquired Cardea Bio Inc.,which she co-founded and ran as the Chief Science Offer. She has also helped co-found CRISPR QC Inc. that offers a CRISPR Analytics Platform that helps pharma and biotech companies optimize their gene editing research. Her overall research and inventions are focused around developing technologies and bioelectronics for multi-omics studies and applications,especially when they enable products and technologies for studying the mechanisms of healthy aging. She became known as the pioneer of fusing CRISPR and electronics,resulting in the CRISPR-chip technology that is being used to improve the quality of genotyping and gene editing. She was awarded the 2021 Nature –Estée Lauder Research Award for Inspiring Women in Science.
Tatiana Segura is an American biomedical engineer who is a professor at Duke University. Her research considers biomedical engineering solutions to promote cell growth. She was elected Fellow of the American Institute for Medical and Biological Engineering in 2017 and awarded the Acta Biomaterialia Silver Medal in 2021.
Kelly Stevens is an American bioengineer and associate professor at the University of Washington. Her research considers the study and development of human platforms to understand and treat disease. She was named a Paul G. Allen Frontiers Fellow in 2022.
Ankur Singh is an Indian-American biomedical engineer and scientist whose research focuses on engineering immune system. He is a Carl Ring Family Endowed Professor at Georgia Institute of Technology in the George W. Woodruff School of Mechanical Engineering and Wallace H. Coulter Department of Biomedical Engineering. He serves as the Director of the Center for Immunoengineering at Georgia Tech.
Jeffrey Hubbell publications indexed by Google Scholar