Brito did not play in a game in 2020 due to the cancellation of the minor league season because of the COVID-19 pandemic.[2] In 2021 he split the year between the High-A Hudson Valley Renegades and Double-A Somerset Patriots, making 22 starts in total and registering a 7–7 record and 3.55 ERA with 118 strikeouts in 116+2⁄3 innings pitched. Brito spent the 2022 season with Somerset and the Triple-A Scranton/Wilkes-Barre RailRiders, pitching to a cumulative 11–4 record and 2.96 ERA with 91 strikeouts in 112+2⁄3 innings across 26 games (23 starts).
On November 10, 2022, the Yankees selected Brito to the 40-man roster to protect him from the Rule 5 draft.[3] Brito was initially optioned to the Triple-A Scranton/Wilkes-Barre to begin the 2023 season.[4] However, after Luis Severino suffered a lat injury, Brito was added to the major league rotation to begin the year.[5] He made his major league debut on April 2.[6] On May 20, Brito was optioned to Triple-A Scranton to make space on the roster for Severino's return.[citation needed]
San Diego Padres
On December 6, 2023, the Yankees traded Brito, Michael King, Drew Thorpe, Randy Vásquez, and Kyle Higashioka to the San Diego Padres in exchange for Juan Soto and Trent Grisham.[7][8] He made 26 appearances for the Padres in 2024, recording a 4.12 ERA with 29 strikeouts across 43+2⁄3 innings pitched. Brito suffered an injury while playing with the Triple–A El Paso Chihuahuas, which was later specified as a right elbow strain. He was placed on the 60–day injured list on September 22, 2024, ending his season.[9]
On April 3, 2025, Brito was placed back on the 60-day injured list with a right forearm strain.[10]
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