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The John J. Abel Award is an annual award presented by the American Society for Pharmacology and Experimental Therapeutics (ASPET). The award is given for outstanding research in the field of pharmacology and/or experimental therapeutics; which comes with a $5000 prize, An engraved plaque, and all travel expenses paid to attend the ASPET Annual Meeting at Experimental Biology. [1] The Award is named after American biochemist and pharmacologist, John Jacob Abel.
Bombesin is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad by Vittorio Erspamer et al. and named after its source. It has two known homologs in mammals called neuromedin B and gastrin-releasing peptide. It stimulates gastrin release from G cells. It activates three different G-protein-coupled receptors known as BBR1, -2, and -3. It also activates these receptors in the brain. Together with cholecystokinin, it is the second major source of negative feedback signals that stop eating behaviour.
John Jacob Abel was an American biochemist and pharmacologist. He established the pharmacology department at Johns Hopkins University School of Medicine in 1893, and then became America's first full-time professor of pharmacology. During his time at Hopkins, he made several important medical advancements, especially in the field of hormone extraction. In addition to his laboratory work, he founded several significant scientific journals such as the Journal of Biological Chemistry and the Journal of Pharmacology and Experimental Therapeutics.
Virgil Craig Jordan,, was an American and British scientist specializing in drugs for breast cancer treatment and prevention. He was Professor of Breast Medical Oncology, and Professor of Molecular and Cellular Oncology at the University of Texas MD Anderson Cancer Center, Houston, Texas. Previously, he was Scientific Director and Vice Chairman of Oncology at the Lombardi Comprehensive Cancer Center of Georgetown University. Jordan was the first to discover the breast cancer prevention properties of tamoxifen and the scientific principles for adjuvant therapy with antihormones. His later work branched out into the prevention of multiple diseases in women with the discovery of the drug group, selective estrogen receptor modulator (SERMs). He later worked on developing a new Hormone Replacement Therapy (HRT) for post-menopausal women that prevents breast cancer and does not increase the risk of breast cancer.
The NASA Exceptional Scientific Achievement Medal was established by NASA on September 15, 1961, when the original ESM was divided into three separate awards. Under its guidelines, the ESAM is awarded for unusually significant scientific contribution toward achievement of aeronautical or space exploration goals. This award may be given for individual efforts that have resulted in a contribution of fundamental importance in this field, or have significantly enhanced understanding of this field.
G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn.
Brian Kent Kobilka is an American physiologist and a recipient of the 2012 Nobel Prize in Chemistry with Robert Lefkowitz for discoveries that reveal the workings of G protein-coupled receptors. He is currently a professor in the department of Molecular and Cellular Physiology at Stanford University School of Medicine. He is also a co-founder of ConfometRx, a biotechnology company focusing on G protein-coupled receptors. He was named a member of the National Academy of Sciences in 2011.
Bernard Beryl Brodie was a founding scientist in the area of biochemical and neurochemical pharmacology whose work in the 1940s and 1950s had great impact. He was a major figure in the fields of drug metabolism and drug therapy, studying how the absorption and interactions of drugs in the body. Brodie helped to found and lead the Laboratory of Chemical Pharmacology at the National Heart Institute in Bethesda, Maryland, one of the National Institutes of Health. He was a member of the United States National Academy of Sciences.
The Journal of Pharmacology and Experimental Therapeutics is a peer-reviewed scientific journal covering pharmacology. It has been published since 1909 by the American Society for Pharmacology and Experimental Therapeutics (ASPET). The journal publishes mainly original research articles, and accepts papers covering all aspects of the interactions of chemicals with biological systems.
The American Society for Pharmacology and Experimental Therapeutics (ASPET) is a scientific society founded in late 1908 by John Jacob Abel of Johns Hopkins University, with the aim of promoting the growth of pharmacological research. Many society members are researchers in basic and clinical pharmacology who help develop disease-fighting medications and therapeutics. ASPET is one of the constituent societies of the Federation of American Societies for Experimental Biology (FASEB). The society's headquarters are in Rockville, MD. The current president is Michael F. Jarvis.
Martin J. Lohse is a German physician and pharmacologist.
Michael J. Kuhar, is an American neuroscientist, author, and Candler Professor of Neuropharmacology at The Emory National Primate Research Center of Emory University. He is a Georgia Research Alliance eminent scholar, and a senior fellow in the Center for Ethics at Emory. He was previously a professor at Johns Hopkins University School of Medicine and branchchief at the National Institute on Drug Abuse.
Arthur Christopoulos is an Australian Professor of Analytical Pharmacology at Monash University. He was a Councillor of the International Union of Basic and Clinical Pharmacology from 2018 to 2022. In 2019 he was appointed Dean of Monash University's Faculty of Pharmacy and Pharmaceutical Sciences and from 2021 to 2023 he served as the inaugural Director of Monash University's Neuromedicines Discovery Centre. He was elected a Fellow of the Australian Academy of Science in 2021.
David Siderovski is a North American pharmacologist. Since March 2020, Siderovski has been Chair of the HSC Department of Pharmacology & Neuroscience at the University of North Texas Health Science Center. From 2012 to 2019, he was the E.J. Van Liere Medicine Professor and Chair of Physiology, Pharmacology & Neuroscience for the West Virginia University School of Medicine.
Angela Hartley Brodie was a British biochemist who pioneered development of steroidal aromatase inhibitors in cancer research. Born in Lancashire, Brodie studied chemical pathology to a doctoral level in Sheffield and was awarded a fellowship sponsored by National Institutes of Health. After 17 years of working in Shrewsbury, Massachusetts on oral contraceptives with Harry Brodie, whom she married, she switched focus to the effects of the oestrogen-producing enzyme, aromatase, on breast cancer.
Salomon Zender Langer is an Argentinian pharmacologist whose family had fled from Poland to Argentina in the early 1930s and were thus saved from the Holocaust during the Second World War.
Dixon Miles Woodbury (1921–1991) was an American epilepsy researcher and distinguished professor of Physiology and Pharmacology at the University of Utah School of Medicine. His research helped clarify the causes of seizure disorders and the mechanisms of anticonvulsant drugs. He published over 300 scientific articles and edited several books on epilepsy, including the first two volumes of Antiepileptic Drugs. His awards include the John Jacob Abel Award from the American Society for Pharmacology and Experimental Therapeutics (ASPET); the Epilepsy Research Award from the International League Against Epilepsy; Research Career Award from the National Institutes of Health; and William G. Lennox Award for outstanding research in epilepsy from the American Epilepsy Society.
Namandjé N. Bumpus is an American pharmacologist who serves as the Principal Deputy Commissioner and Acting Chief Scientist of the Food and Drug Administration. She was previously director of the department of pharmacology and molecular sciences at Johns Hopkins University School of Medicine, where she holds the E.K. Marshall and Thomas H. Maren professorship in pharmacology. Bumpus is known for her research on the metabolism of antiviral drugs used to treat HIV-1 and how genetic variations in drug-processing enzymes may impact these drugs' efficacy. Bumpus received a Presidential Early Career Award for Scientists and Engineers in 2016. The Food and Drug Administration’s top scientist Namandjé Bumpus has assumed the role of principal deputy commissioner when longtime agency leader Janet Woodcock retired from that role in January 2024.
Lee Limbird is a pharmacologist, Dean of the School of Natural Science, Mathematics and Business & Professor in the Department of Life and Physical Sciences at Fisk University, Nashville, Tennessee.
Eva King Killam was a research pharmacologist who studied the activity of drugs on the brain and behavior, developing animal models for epilepsy and opiate dependence.