Related Research Articles
Peptic ulcer disease (PUD) is a break in the inner lining of the stomach,the first part of the small intestine,or sometimes the lower esophagus. An ulcer in the stomach is called a gastric ulcer,while one in the first part of the intestines is a duodenal ulcer. The most common symptoms of a duodenal ulcer are waking at night with upper abdominal pain and upper abdominal pain that improves with eating. With a gastric ulcer,the pain may worsen with eating. The pain is often described as a burning or dull ache. Other symptoms include belching,vomiting,weight loss,or poor appetite. About a third of older people have no symptoms. Complications may include bleeding,perforation,and blockage of the stomach. Bleeding occurs in as many as 15% of cases.
Millburn is a suburban township in Essex County,New Jersey,United States. As of the 2010 United States Census,the township's population is 20,149,reflecting an increase of 384 (+1.9%) from the 19,765 counted in the 2000 Census,which had in turn increased by 1,135 (+6.1%) from the 18,630 counted in the 1990 Census. Short Hills is an upscale section and unincorporated community within Millburn.
Helicobacter pylori,previously known as Campylobacter pylori,is a gram-negative,microaerophilic,spiral (helical) bacterium usually found in the stomach. Its helical shape is thought to have evolved in order to penetrate the mucoid lining of the stomach and thereby establish infection. The bacterium was first identified in 1982 by the Australian doctors Barry Marshall and Robin Warren. H. pylori has been associated with cancer of the mucosa-associated lymphoid tissue in the stomach,esophagus,colon,rectum,or tissues around the eye,and of lymphoid tissue in the stomach.
Stomach cancer,also known as gastric cancer,is a cancer that develops from the lining of the stomach. Most cases of stomach cancers are gastric carcinomas,which can be divided into a number of subtypes,including gastric adenocarcinomas. Lymphomas and mesenchymal tumors may also develop in the stomach. Early symptoms may include heartburn,upper abdominal pain,nausea,and loss of appetite. Later signs and symptoms may include weight loss,yellowing of the skin and whites of the eyes,vomiting,difficulty swallowing,and blood in the stool,among others. The cancer may spread from the stomach to other parts of the body,particularly the liver,lungs,bones,lining of the abdomen,and lymph nodes.
Barry James Marshall is an Australian physician,Nobel Prize Laureate in Physiology or Medicine,Professor of Clinical Microbiology and Co-Director of the Marshall Centre at the University of Western Australia. Marshall and Robin Warren showed that the bacterium Helicobacter pylori plays a major role in causing many peptic ulcers,challenging decades of medical doctrine holding that ulcers were caused primarily by stress,spicy foods,and too much acid. This discovery has allowed for a breakthrough in understanding a causative link between Helicobacter pylori infection and stomach cancer.
Julie Louise Gerberding is an American infectious disease expert who was the first woman to serve as the director of the U.S. Centers for Disease Control and Prevention (CDC). As of May 2022,she is the CEO of the Foundation for the National Institutes of Health (FNIH). Gerbering grew up in Estelline,South Dakota,attended Brookings High School,and earned undergraduate and graduate degrees from Case Western Reserve University. She was the chief medical resident at the University of California,San Francisco where she treated hospitalized AIDS patients in the first years of the epidemic. Gerberding became a nationally-recognized figure during the 2001 anthrax attacks in the United States during her tenure as the acting deputy director of the National Center for Infectious Diseases,where she was a prominent spokeswoman for the CDC during daily briefings regarding the attacks and aftermath. Gerberding then served as CDC director from 2002-2009,and was then hired as an administrator at Merck. She retired in May 2022 and moved on to the FNIH.
Millburn High School is a four-year public high school serving students in ninth through twelfth grades from Millburn,in Essex County,New Jersey,United States,operating as the lone secondary school of the Millburn Township Public Schools. The school was honored with National Blue Ribbon School Award of Excellence in the 2007–08 school year and was named the top-ranked high school in the state in the September 2008 and 2010 issues of New Jersey Monthly.
Martin J. Blaser is the director of the Center for Advanced Biotechnology and Medicine at Rutgers (NJ) Biomedical and Health Sciences and the Henry Rutgers Chair of the Human Microbiome and Professor of Medicine and Pathology and Laboratory Medicine at the Rutgers Robert Wood Johnson Medical School in New Jersey.
Yuan Chang is a Taiwanese-American virologist and pathologist who co-discovered together with her husband,Patrick S. Moore,the Kaposi's sarcoma-associated herpesvirus (KSHV) and Merkel cell polyomavirus,two of the seven known human oncoviruses.
Millburn is a New Jersey Transit station in Millburn,New Jersey along the Morristown and Gladstone lines.
This is a timeline of the events relating to the discovery that peptic ulcer disease and some cancers are caused by H. pylori. In 2005,Barry Marshall and Robin Warren were awarded the Nobel Prize in Physiology or Medicine for their discovery that peptic ulcer disease (PUD) was primarily caused by Helicobacter pylori,a bacterium with affinity for acidic environments,such as the stomach. As a result,PUD that is associated with H. pylori is currently treated with antibiotics used to eradicate the infection. For decades prior to their discovery,it was widely believed that PUD was caused by excess acid in the stomach. During this time,acid control was the primary method of treatment for PUD,to only partial success. Among other effects,it is now known that acid suppression alters the stomach milieu to make it less amenable to H. pylori infection.
Cancer bacteria are bacteria infectious organisms that are known or suspected to cause cancer. While cancer-associated bacteria have long been considered to be opportunistic,there is some evidence that bacteria may be directly carcinogenic. The strongest evidence to date involves the bacterium H. pylori and its role in gastric cancer.
Estimates place the worldwide risk of cancers from infectious causes at 16.1%. Viral infections are risk factors for cervical cancer,80% of liver cancers,and 15–20% of the other cancers. This proportion varies in different regions of the world from a high of 32.7% in Sub-Saharan Africa to 3.3% in Australia and New Zealand. Helicobacter pylori is associated with stomach cancer,and Mycobacterium,some other bacteria and parasites also have an effect.
Lucy S. Tompkins is a practicing internist,the Lucy Becker Professor of Medicine for infectious diseases at Stanford University,and a professor of microbiology and immunology. Since 1989,she has been the Epidemiologist and Medical Director of the Infection Control and Epidemiology Department for Stanford Hospital. She also has been the Associate Dean for Academic Affairs at the Stanford School of Medicine since 2001. She has been the recipient of multiple fellowships throughout her career,including the American Association for the Advancement of Science. Her current research centers around healthcare-related infections and bacterial pathogenesis.
Dean Winslow is an American physician,academic,and retired United States Air Force colonel. He had been nominated by President Donald Trump to become the next Assistant Secretary of Defense for Health Affairs,but he withdrew his nomination in December 2017 after it was put on indefinite hold. He is Professor and former Vice Chair of Medicine at Stanford University. He previously served as Chair of the Department of Medicine and Chief of the Division of AIDS Medicine at the Santa Clara Valley Medical Center. In the Air Force,he deployed twice to Afghanistan and four times to Iraq as a flight surgeon supporting combat operations in Operation Enduring Freedom and Operation Iraqi Freedom.
Michele Barry is a professor of medicine,and director of the Center for Innovation in Global Health and Senior Associate Dean for Global Health,both at Stanford University,where she entered after 28 years working at Yale. She specializes in tropical medicine,emerging infectious diseases,and in the globalization induced health problems of low income countries.
Helen Boucher is Dean ad interim of the Tufts University School of Medicine and Chief Academic Officer of Wellforce,the parent health system for Tufts Medical Center in Boston. Prior to this,she served as Chief of the Division of Geographic Medicine and Infectious Diseases at Tufts Medical Center,a Professor of Medicine at Tufts University School of Medicine,and Director of the Stuart B. Levy Center for Integrated Management of Antimicrobial Resistance at Tufts.
Rochelle Paula Walensky is an American physician-scientist who is the director of the Centers for Disease Control and Prevention and the administrator of the Agency for Toxic Substances and Disease Registry. Prior to her appointment at the CDC,she was the Chief of the Division of Infectious Diseases at Massachusetts General Hospital and a professor of medicine at Harvard Medical School. Walensky is an expert on HIV/AIDS.
Geeta Krishna Swamy is an American OBGYN. She is a professor of obstetrics and gynecology at Duke University and Associate Vice President for Research and Vice Dean for Scientific Integrity.
References
- 1 2 "Marriage of Parsonnet". Millburn, New Jersey: The Item of Millburn and Short Hills. February 4, 1993. Retrieved May 19, 2021– via newspapers.com.
- ↑ "JULIE PARSONNET". The Item of Millburn and Short Hills. June 14, 1979. Retrieved May 19, 2021– via newspapers.com.
- ↑ "SUMMER INTERNSHIP". The Item of Millburn and Short Hills. September 21, 1978. Retrieved May 19, 2021– via newspapers.com.
- ↑ "Julie Parsonnet heads medical school class". The Item of Millburn and Short Hills. July 28, 1983. Retrieved May 19, 2021– via newspapers.com.
- ↑ "Julie Parsonnet". profiles.stanford.edu. Retrieved May 19, 2021.
- ↑ "Society awards research grant to Dr. Parsonnet". The Item of Millburn and Short Hills. February 14, 1991. Retrieved May 19, 2021– via newspapers.com.
- ↑ "Julie Parsonnet, MD". the-asci.org. Retrieved May 19, 2021.
- ↑ "Anthony Alfrey Ph.D." legacy.com. Retrieved May 19, 2021.
- ↑ "Dean Winslow". profiles.stanford.edu. Retrieved May 19, 2021.
- ↑ Kearly, Kendyl (November 19, 2020). "Drs. Julie Parsonnet And Dean Winslow Are A Pandemic-Fighting Team". mlsiliconvalley.com. Retrieved May 19, 2021.
- ↑ "National Academy of Medicine Elects 100 New Members". nam.edu. October 1, 2019. Retrieved May 19, 2021.
