Keratin associated protein 5-6

KRTAP5-6
Identifiers
Aliases	KRTAP5-6 , KRTAP5.6, keratin associated protein 5-6
External IDs	GeneCards: KRTAP5-6
Gene location (Human)
Chr.	Chromosome 11 (human)
End	1,697,755 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; placenta; ; stromal cell of endometrium; ; ganglionic eminence; ; gallbladder; ; prefrontal cortex; ; lymph node; ; skin of abdomen; ; right lung; ; islet of Langerhans;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding ;
Cellular component	intermediate filament ; cytosol ; keratin filament ;
Biological process	keratinization ;
	Sources:Amigo / QuickGO
Orthologs
	440023
	n/a
	ENSG00000205864 ; ENSG00000277389
	n/a
	Q6L8G9
	n/a
	NM_001012416
	n/a
	NP_001012416
	n/a
	Wikidata
View/Edit Human

Last updated October 01, 2023

Keratin associated protein 5-6 is a protein that in humans is encoded by the KRTAP5-6 gene. ^[3]

Related Research Articles

Keratin 6A is one of the 27 different type II keratins expressed in humans. Keratin 6A was the first type II keratin sequence determined. Analysis of the sequence of this keratin together with that of the first type I keratin led to the discovery of the four helical domains in the central rod of keratins. In humans Keratin 6A is encoded by the KRT6A gene.

Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by the KRT4 gene.

Keratin 3 also known as cytokeratin 3 is a protein that in humans is encoded by the KRT3 gene. Keratin 3 is a type II cytokeratin. It is specifically found in the corneal epithelium together with keratin 12.

Keratin 14 is a member of the type I keratin family of intermediate filament proteins. Keratin 14 was the first type I keratin sequence determined. Keratin 14 is also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14). In humans it is encoded by the KRT14 gene.

Keratin 13 is a protein that in humans is encoded by the KRT13 gene.

Keratin 12 is a protein that in humans is encoded by the KRT12 gene.

Keratin, type I cytoskeletal 19 also known as cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. Keratin 19 is a type I keratin.

Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

Keratin 16 is a protein that in humans is encoded by the KRT16 gene.

Keratin 6C, is a type II cytokeratin, one of a number of isoforms of keratin 6 encoded by separate genes located within the type II keratin gene cluster on human chromosome 12q. This gene was uncovered recently by the Human Genome Project and its expression patterns in humans remains unknown.

Keratin, type II cuticular Hb1 is a protein that in humans is encoded by the KRT81 gene.

Keratin, type II cuticular Hb6 is a protein that in humans is encoded by the KRT86 gene.

Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.

Keratin, type I cytoskeletal 23 is a protein that in humans is encoded by the KRT23 gene.

Keratin, type I cuticular Ha2 is a protein that in humans is encoded by the KRT32 gene.

Keratin, type I cuticular Ha4 is a protein that in humans is encoded by the KRT34 gene.

Keratin, type I cuticular Ha6 is a protein that in humans is encoded by the KRT36 gene.

Keratin 83, also known as KRT83, is a protein which humans is encoded by the KRT83 gene.

Keratin 79 also known as KRT79 is a protein which humans is encoded by the KRT79 gene.

KRT71 is a keratin gene. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q13.

References

1 2 3 ENSG00000277389 GRCh38: Ensembl release 89: ENSG00000205864, ENSG00000277389 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Keratin associated protein 5-6" . Retrieved 2017-12-02.

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[refGRCh38Ensembl-1] 1 2 3 ENSG00000277389 GRCh38: Ensembl release 89: ENSG00000205864, ENSG00000277389 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: Keratin associated protein 5-6" . Retrieved 2017-12-02.

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