Lenampicillin

Lenampicillin
Clinical data
Trade names	Takacillin, Varacillin
Other names	KBT-1585
Legal status
Legal status	Rx in Japan;
Identifiers
	IUPAC name (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;
CAS Number	86273-18-9 ;
PubChem CID	65646 ;
UNII	8M568DM08K ;
CompTox Dashboard (EPA)	DTXSID1057901 ;
Chemical and physical data
Formula	C21H23N3O7S
Molar mass	461.49 g·mol−1

Last updated July 01, 2025

Lenampicillin is an antibiotic drug of the penicillin class. It is a prodrug of ampicillin; after oral administration of lenampicillin, ampicillin is rapidly formed.^[1]

Lenampicillin inhibits bacterial penicillin binding proteins (transpeptidase) and is effective against a wide range of bacterial infections.^[2]

Lenampicillin was developed in Japan and has been marketed there.^[2]

References

↑ Saito A, Nakashima M (May 1986). "Pharmacokinetic study of lenampicillin (KBT-1585) in healthy volunteers". Antimicrobial Agents and Chemotherapy. 29 (5): 948–950. doi:10.1128/aac.29.5.948. PMC 284190 . PMID 3729355.
1 2 "Lenampicillin". InxightDrugs. National Center for Advancing Translational Sciences.

This systemic antibiotic-related article is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[1] Saito A, Nakashima M (May 1986). "Pharmacokinetic study of lenampicillin (KBT-1585) in healthy volunteers". Antimicrobial Agents and Chemotherapy. 29 (5): 948–950. doi:10.1128/aac.29.5.948. PMC 284190 . PMID 3729355.

[ncats-2] 1 2 "Lenampicillin". InxightDrugs. National Center for Advancing Translational Sciences.

[1]

[2]