Lichen myxedematosus

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Lichen myxedematosus
Specialty Dermatology   OOjs UI icon edit-ltr-progressive.svg

Lichen myxedematous is a group of cutaneous disorders considered mucinoses. [1] [2] Conditions included in this group are: [2]

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Lichen planus (LP) is a chronic inflammatory and autoimmune disease that affects the skin, nails, hair, and mucous membranes. It is not an actual lichen, but is named for its appearance. It is characterized by polygonal, flat-topped, violaceous papules and plaques with overlying, reticulated, fine white scale, commonly affecting dorsal hands, flexural wrists and forearms, trunk, anterior lower legs and oral mucosa. The hue may be gray-brown in people with darker skin. Although there is a broad clinical range of LP manifestations, the skin and oral cavity remain as the major sites of involvement. The cause is unknown, but it is thought to be the result of an autoimmune process with an unknown initial trigger. There is no cure, but many different medications and procedures have been used in efforts to control the symptoms.

Papular mucinosis is a rare skin disease. Localized and disseminated cases are called papular mucinosis or lichen myxedematosus while generalized, confluent papular forms with sclerosis are called scleromyxedema. Frequently, all three forms are regarded as papular mucinosis. However, some authors restrict it to only mild cases. Another form, acral persistent papular mucinosis is regarded as a separate entity.

Gianotti–Crosti syndrome, also known as infantile papular acrodermatitis, papular acrodermatitis of childhood, and papulovesicular acrolocated syndrome, is a reaction of the skin to a viral infection. Hepatitis B virus and Epstein–Barr virus are the most frequently reported pathogens. Other viruses implicated are hepatitis A virus, hepatitis C virus, cytomegalovirus, coxsackievirus, adenovirus, enterovirus, rotavirus, rubella virus, HIV, and parainfluenza virus.

Prurigo gestationis is an eruption consisting of pruritic, excoriated papules of the proximal limbs and upper trunk, most often occurring between the 20th and 34th week of gestation.

Alopecia mucinosa, also known as Follicular mucinosis, Mucinosis follicularis, Pinkus' follicular mucinosis, and Pinkus' follicular mucinosis–benign primary form, is a skin disorder that generally presents, but not exclusively, as erythematous plaques or flat patches without hair primarily on the scalp, neck and face. This can also be present on the body as a follicular mucinosis and may represent a systemic disease.

<span class="mw-page-title-main">Lichen striatus</span> Medical condition

Lichen striatus is a rare skin condition that is seen primarily in children, most frequently appearing ages 5–15. It consists of a self-limiting eruption of small, scaly papules.

Localized lichen myxedematosus is a group of skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides, a disease for which there is no treatment.

Discrete papular lichen myxedematosus is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides characterized by the occurrence of waxy, flesh-colored papules..

Acral persistent papular mucinosis (APPM) is a rare form of lichen myxedematosus. It is characterized by small papules on the backs of the hands, wrists, and extensor aspects of the distal forearms, with no further clinical or laboratory indications. Lesions tend to persist and may grow in number gradually. Because there are no symptoms, treatment is rarely required.

Self-healing papular mucinosis is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides, and may present in adult and juvenile forms. The juvenile variant is also called self-healing juvenile cutaneous mucinosis.

Self-healing juvenile cutaneous mucinosis is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides, and is characterized by the sudden onset of skin lesions and polyarthritis.

Papular mucinosis of infancy is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides, characterized by skin-colored or translucent papules.

Atypical lichen myxedematosus is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides.

<span class="mw-page-title-main">Cutaneous lymphoid hyperplasia</span> Medical condition

Cutaneous lymphoid hyperplasia refers to a groups of benign cutaneous disorders characterized by collections of lymphocytes, macrophages, and dendritic cells in the skin. Conditions included in this groups are:

Urticaria-like follicular mucinosis is a rare cutaneous disorder that occurs primarily in middle-aged men.

Atypical tuberous myxedema, also known as Jadassohn–Dosseker syndrome, is thought to represent a pure nodular variant of lichen myxedematosus.

Stiff skin syndrome is a cutaneous condition characterized by ‘rock hard’ induration, thickening of the skin and subcutaneous tissues, limited joint mobility, and mild hypertrichosis in infancy or early childhood. Immunologic abnormalities or vascular hyperactivity are not present in patients.

Nodular lichen myxedematosus is a cutaneous condition characterized by multiple nodules on the limbs and trunk, with a mild or absent papular component.

Cutaneous lupus mucinosis, also known as papular and nodular mucinosis in lupus erythematosus, papular and nodular mucinosis of Gold, and papulonodular mucinosis in lupus erythematosus, is a cutaneous condition characterized by lesions that present as asymptomatic skin-colored, at times reddish, 0.5–2 cm papules and nodules.

References

  1. Rapini RP, Bolognia JL, Jorizzo JL (2007). Dermatology: 2-Volume Set (2nd ed.). St. Louis: Mosby. ISBN   978-1-4160-2999-1.
  2. 1 2 James WD, Berger TG, Elston DM, Neuhaus IM, Micheletti RG (2016). "Chapter 9: Mucinoses: Lichen Myxedematosus". Andrews' Diseases of the Skin: Clinical Dermatology (12th ed.). Philadelphia: Saunders Elsevier. pp. 179–182. ISBN   978-0-323-31967-6.