Fitzpatrick's early work was at the Center for Disease Control and Prevention where she specialized in the investigation of tuberculosis[2] and was a diplomat in global health in the Caribbean.[3] She also worked on education of people about HIV/AIDS while she worked in the San Francisco Department of Health and in this context she spoke with the Washington Post about getting people tested for HIV.[4] Her published work in this realm assessed people's thoughts on the medical care they received regarding tuberculosis and health disparities in communities affected by HIV.[5][6] Fitzpatrick founded Grapevine Health to improve health literacy and education for under-resourced communities[7] and, as of 2022, she is a lecturer and adjunct professor at George Washington University School of Medicine & Health Sciences[8] and the
Fitzpatrick is known for her work in increasing people's understanding of human health, particularly with respect to personal health.[9][10] During the COVID-19 pandemic, Fitzpatrick shared her experience with getting vaccinated with other people in order to encourage other people to get vaccinated.[3] She goes by "Dr. Lisa" while presenting outreach, a program where she interacts with people on the street to talk about healthcare.[3] In 2020 Fitzpatrick was named as one of five people who will serve as Joe Biden's committee for healthcare policy,[11] and she is a member of the round table on health literacy group at the National Academies of Science, Engineering, and Medicine.[12]
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