| Title | Series | Issues | Dates | Notes |
|---|
| Saban's Mighty Morphin Power Rangers | | #1–7 | Oct 1995 – may 1996 | |
| Ninja Rangers/VR Troopers | #1–5 | Dec 1995 – Apr 1996 | |
| Sable & Fortune | | #1–4 | Mar – Jun 2006 | limited series |
| Sabretooth | vol. 1 | #1–4 | Aug – Dec 1993 | limited series |
| vol. 2 | #1 | Jan 1998 | one-shot |
| vol. 3 | Special #1 | Jan 1995 | one-shot |
| vol. 4 | #1–4 | Dec 2004 – Feb 2005 | limited series |
| Mary Shelley Overdrive | #1–4 | Aug – Nov 2002 | limited series |
| Sabretooth Classic | | #1–15 | May 1994 – Jul 1995 | |
| The Saga of Crystar, Crystal Warrior | | #1–11 | May 1983 – Feb 1985 | |
| The Saga of the Original Human Torch | | #1–4 | Apr – Jul 1990 | limited series |
| Saga of Squadron Supreme | | #1 | Jan 2006 | one-shot |
| Saga of the Sub-Mariner | | #1–12 | Nov 1988 – Oct 1989 | limited series |
| Saint Sinner | | #1–7 | Oct 1993 – Apr 1994 | |
| Saturday Morning: The Comic | | #1 | Mar 1996 | one-shot; tie-in with the Saturday Morning: Cartoons' Greatest Hits album |
| Savage Avengers | | #1– | Jul 2019 – present | |
| The Savage Axe of Ares | | #1 | Jun 2010 | one-shot |
| The Savage Hulk | vol. 1 | | Jan 1996 | one-shot |
| vol. 2 | #1–6 | Aug 2014 – Jan 2015 | |
| The Savage Return of Dracula | | #1 | 1992 | one-shot |
| The Savage She-Hulk | | #1–25 | Feb 1980 – Feb 1982 | |
| The Savage Sword of Conan | vol. 1 | #1–235 | Aug 1974 – Jul 1995 | |
| vol. 2 | #1– | Apr 2019 – present | |
| Savage Tales | vol. 1 | #1–12 | May 1971 – Aug 1975 | |
| vol. 2 | #1–8 | Oct 1985 – Dec 1986 | |
| Savage Wolverine | | #1–23 | Mar 2013 – Nov 2014 | |
| Scarlet Spider | vol. 1 | #1–2 | Nov – Dec 1995 | between issues 63 and 64 of Spider-Man vol. 1 |
| vol. 2 | #1–25
12.1 | Mar 2012 – Feb 2014 | |
| Scarlet Spider Unlimited | | #1 | Nov 1995 | one-shot |
| Scarlet Spiders | | #1–3 | Jan – Mar 2015 | limited series |
| Scarlet Witch | vol. 1 | #1–4 | Jan – Apr 1994 | limited series |
| vol. 2 | #1–15 | Feb 2016 – Apr 2017 | |
| Scooby-Doo | | #1–9 | Oct 1977 – Feb 1979 | |
| Scorpio Rising: Wolverine / Nick Fury | | | Oct 1994 | one-shot |
| The Screwtape Letters | | | Jun 1994 | graphic novel adaptation |
| Season One | Ant-Man | | 2012 | graphic novel |
| Avengers | | 2012 | graphic novel |
| Daredevil | | 2012 | graphic novel |
| Doctor Strange | | 2012 | graphic novel |
| Fantastic Four | | 2012 | graphic novel |
| Hulk | | 2012 | graphic novel |
| Iron Man | | 2013 | graphic novel |
| Spider-Man | | 2012 | graphic novel |
| Thor | | 2013 | graphic novel |
| Wolverine | | 2013 | graphic novel |
| X-Men | | 2012 | graphic novel |
| Season's Beatings | | #1 | Feb 2019 | one-shot |
| Secret Avengers | vol. 1 | #1–37
12.1, 21.1 | Jul 2010 – Apr 2013 | |
| vol. 2 | #1–16 | Apr 2013 – Apr 2014 | |
| vol. 3 | #1–15 | May 2014 – Jun 2015 | |
| The Secret Defenders | | #1–25 | Mar 1993 – Mar 1995 | |
| Secret Empire | | #0–10 | Jun – Oct 2017 | limited series |
| Brave New World | #1–5 | Aug – Oct 2017 | |
| Omega | #1 | Nov 2017 | one-shot |
| Underground | #1 | Aug 2017 | one-shot |
| United | #1 | Aug 2017 | one-shot |
| Uprising | #1 | Jul 2017 | one-shot |
| Secret Invasion | | #1–8 | Jun 2008 – Jan 2009 | limited series |
| Dark Reign | #1 | Feb 2009 | one-shot |
| Fantastic Four | #1–3 | Jul – Sep 2008 | limited series |
| Front Line | #1–5 | Sep 2008 – Jan 2009 | limited series |
| Inhumans | #1–4 | Oct 2008 – Jan 2009 | limited series |
| Requiem | #1 | Jan 2009 | one-shot |
| Runaways / Young Avengers | #1–3 | Aug – Nov 2009 | limited series |
| Saga | #1 | 2008 | one-shot |
| The Amazing Spider-Man | #1–3 | Oct – Dec 2008 | limited series |
| Thor | #1–3 | Oct – Dec 2008 | limited series |
| War of Kings | #1 | Mar 2009 | one-shot |
| Who Do You Trust? | #1 | Aug 2008 | one-shot |
| X-Men | #1–4 | Oct 2008 – Jan 2009 | limited series |
| Secret Invasion Aftermath: Beta Ray Bill – The Green of Eden | | #1 | Jun 2009 | one-shot |
| Secret War | | #1–5 | Apr 2004 – Dec 2005 | limited series |
| From the Files of Nick Fury | #1 | Jul 2005 | one-shot |
| Secret Warps | Arachknight | Annual #1 | Sep 2019 | one-shot |
| Ghost Panther | Annual #1 | Sep 2019 | one-shot |
| Iron Hammer | Annual #1 | Sep 2019 | one-shot |
| Soldier Supreme | Annual #1 | Sep 2019 | one-shot |
| Weapon Hex | Annual #1 | Sep 2019 | one-shot |
| Secret Warriors | vol. 1 | #1–28 | Apr 2009 – Sep 2011 | |
| vol. 2 | #1–12 | Jul 2017 – Mar 2018 | |
| Secret Wars | | #1–9 | Jul 2015 – Mar 2016 | limited series |
| 2099 | #1–5 | Jul – Nov 2015 | limited series |
| Agents of Atlas | #1 | Dec 2015 | one-shot |
| Battleworld | #1–4 | Jul – Oct 2015 | limited series |
| Journal | #1–5 | Jul – Nov 2015 | limited series |
| Official Guide to the Marvel Multiverse | #1 | Dec 2015 | one-shot |
| Secret Love | #1 | Oct 2015 | one-shot |
| Too | #1 | Jan 2016 | one-shot |
| Secret Wars II | | #1–9 | Jul 1985 – Mar 1986 | limited series |
| Secrets of the House of M | | | Sep 2005 | one-shot |
| Sectaurs | | #1–8 | Jun 1985 – Sep 1986 | |
| Seeker 3000 | | #1–4 | Jun – Sep 1998 | limited series |
| Semper Fi | | #1–9 | Dec 1988 – Aug 1989 | |
| The Sensational She-Hulk | | #1–60 | May 1989 – Feb 1994 | |
| Ceremony | #1–2 | 1989 | limited series |
| The Sensational Spider-Man | vol. 1 | #0–33
-1 | Jan 1996 – Nov 1998 | |
| '96 | Nov 1996 | Annual |
| vol. 2 | #23–41 | Apr 2006 – Dec 2007 | continues from Marvel Knights Spider-Man vol. 1 |
| Annual #1 | 2007 | |
| vol. 3 | #33.1–33.2 | Oct 2012 | limited series |
| Self-Improvement | #1 | Oct 2019 | one-shot |
| Sense & Sensibility | | #1–5 | Jul – Nov 2010 | limited series |
| Sentinel | vol. 1 | #1–12 | Jun 2003 – Apr 2004 | |
| vol. 2 | #1–5 | Jan – May 2006 | limited series |
| Sentinel Squad O*N*E | | #1–5 | Mar – Jul 2006 | limited series |
| Sentry | vol. 1 | #1–5 | Sep 2000 – Jan 2001 | limited series, as "The Sentry" |
| vol. 2 | #1–8 | Nov 2005 – Jun 2006 | limited series |
| vol. 3 | #1–5 | Aug 2018 – Dec 2018 | limited series |
| Fallen Sun | #1 | Jul 2010 | one-shot |
| Reborn | #1 | 2006 | one-shot |
| The Sentry / | Fantastic Four | #1 | Feb 2001 | one-shot |
| Hulk | #1 | Feb 2001 | one-shot |
| Spider-Man | #1 | Feb 2001 | one-shot |
| The Void | #1 | Feb 2001 | one-shot |
| X-Men | #1 | Feb 2001 | one-shot |
| Sergio Aragonés Massacres Marvel | | #1 | Jun 1996 | one-shot |
| Sex, Lies and Mutual Funds of the Yuppies From Hell | | #1 | Jan 1992 | one-shot |
| Sgt. Fury | | #1–120 | May 1963 – Jun 1974 | continues with Sgt. Fury and his Howling Commandos |
| Annual #1–7 | 1965 – Nov 1971 | |
| Sgt. Fury and his Howling Commandos | vol. 1 | #121–167 | Sep 1974 – Dec 1981 | continues from Sgt. Fury |
| vol. 2 | #1 | Jul 2009 | one-shot |
| Shadowland | | #1–5 | Sep 2010 – Jan 2011 | limited series |
| After the Fall | #1 | Feb 2011 | one-shot |
| Blood on the Streets | #1–4 | Oct 2010 – Jan 2011 | limited series |
| Bullseye | #1 | Oct 2010 | one-shot |
| Daughters of the Shadow | #1–3 | 2010 – Jan 2011 | limited series |
| Elektra | #1 | Nov 2010 | one-shot |
| Ghost Rider | #1 | Nov 2010 | one-shot |
| Moon Knight | #1–3 | 2010 | limited series |
| Power Man | #1–4 | Oct 2010 – Jan 2011 | limited series |
| Spider-Man | #1 | Dec 2010 | one-shot |
| Shadowmasters | | #1–4 | Oct 1989 – Jan 1990 | limited series |
| Shadow Riders | | #1–4 | Jun – Sep 1993 | limited series |
| Shadows & Light | | #1–3 | Feb – Jul 1998 | limited series |
| Shame Itself | | #1 | Jan 2012 | one-shot |
| Shang-Chi: Master of Kung Fu | vol. 1 | #1–6 | Nov 2002 – Apr 2003 | limited series |
| vol. 2 | #1 | Nov 2009 | one-shot |
| Shanna the She-Devil | vol. 1 | #1–5 | Dec 1972 – Aug 1973 | |
| vol. 2 | #1–7 | Apr – Oct 2005 | limited series |
| Survival of the Fittest | #1–4 | Oct 2007 – Jan 2008 | limited series |
| Shatterstar | | #1–5 | Dec 2018 – Apr 2019 | limited series |
| She-Hulk | vol. 1 | #1–12 | May 2004 – Apr 2005 | |
| vol. 2 | #1–38 | Dec 2005 – Apr 2009 | |
| vol. 3 | #1–12 | Apr 2014 – Apr 2015 | |
| vol. 4 | #159–163 | Jan 2018 – May 2018 | continues (and renumbered) from Hulk vol. 5 |
| Annual | #1 | Oct 2019 | one-shot |
| Cosmic Collision | #1 | Feb 2009 | one-shot |
| Sensational | #1 | May 2010 | one-shot |
| She-Hulks | | #1–4 | Jan – Ape 2011 | limited series |
| Sheena | | #1–2 | Dec 1984 – Feb 1985 | limited series, adaptation of the 1984 film |
| Shi/Wolverine: Judgment Night | | #1 | 2000 | one-shot; co-published with Crusade Comics |
| S.H.I.E.L.D. | vol. 1 | #1–5 | Feb – Oct 1973 | labeled as SHIELD without the periods
also known as Nick Fury and His Agents of SHIELD |
| vol. 2 | #1–6 | Jun 2010 – Apr 2011 | |
| vol. 3 | #∞
1–6 | Jun 2011 – Feb 2018 | six-year delay between issues 4 & 5 |
| vol. 4 | #1–12 | Feb 2015 – Jan 2016 | |
| Shogun Warriors | | #1–20 | Feb 1979 – Sep 1989 | |
| The Shroud | | #1–4 | Mar – Jun 1994 | limited series |
| Shuri | | #1–10 | Dec 2018 – Sep 2019 | |
| Siege | vol. 1 | #1–4 | Mar – Jun 2010 | limited series |
| vol. 2 | #1–4 | Sep – Dec 2015 | limited series |
| Captain America | #1 | Jun 2010 | one-shot |
| Embedded | #1–4 | Mar – Jul 2010 | limited series |
| Loki | #1 | Jun 2010 | one-shot |
| Secret Warriors | #1 | Jun 2010 | one-shot |
| Spider-Man | #1 | Jun 2010 | one-shot |
| Storming Asgard - Heroes & Villains | #1 | Mar 2010 | one-shot |
| The Cabal | #1 | Feb 2010 | one-shot |
| Young Avengers | #1 | Jun 2010 | one-shot |
| Sif | | #1 | Jun 2010 | one-shot |
| Silent War | | #1–6 | Mar – Aug 2007 | limited series |
| Silk | vol. 1 | #1–7 | Apr – Nov 2015 | |
| vol. 2 | #1–19 | Jan 2016 – Jun 2017 | |
| Silver Sable and the Wild Pack | vol. 1 | #1–35 | Jun 1992 – Apr 1995 | |
| vol. 2 | #1 | Jan 2018 | one-shot |
| Silver Surfer | vol. 1 | #1–18 | Aug 1968 – Sep 1970 | |
| vol. 2 | #1 | 1982 | one-shot |
| vol. 3 | #1–146
-1 | Jul 1987 – Nov 1998 | |
| '97 | 1997 | Annual |
| Silver Surfer/Thor '98 | 1998 | Annual |
| Annual #1–7 | 1988 – 1994 | |
| vol. 4 | #1–14 | Sep 2003 – Dec 2004 | |
| vol. 5 | #1–5 | Apr – Aug 2011 | limited series |
| vol. 6 | #1–15 | May 2014 – Jan 2016 | |
| vol. 7 | #1–14 | Mar 2016 – Dec 2017 | |
| vol. 8 | Annual #1 | Nov 2018 | one-shot |
| Black | #1–5 | Aug 2019 – present | limited series |
| Dangerous Artifacts | #1 | Jun 1996 | one-shot |
| In Thy Name | #1–4 | Jan – Apr 2008 | limited series |
| Loftier Than Mortals | #1–2 | Oct 1999 | limited series |
| Parable | #1–2 | Dec 1988 – Jan 1989 | limited series |
| The Prodigal Sun | #1 | Oct 2019 | one-shot |
| The Ultimate Cosmic Experience! | | 1978 | graphic novel; co-published with Fireside Books |
| Requiem | #1–4 | Jul – Oct 2007 | limited series |
| Silver Surfer / | Superman | #1 | Nov 1996 | one-shot; co-published with DC |
| Warlock: Resurrection | #1–4 | Mar – Jun 1993 | limited series |
| Weapon Zero | #1 | Apr 1997 | one-shot; co-published with Top Cow Productions and Image Comics |
| Silver Surfer vs. Dracula | | #1 | Feb 1994 | one-shot |
| Six Guns | | #1–5 | Jan – Apr 2012 | limited series |
| Skaar | King of the Savage Land | #1–5 | Jun – Sep 2011 | limited series |
| Son of Hulk | #1–12 | Aug 2008 – Aug 2009 | continues as Son of Hulk |
| Son of Hulk Presents - Savage World of Sakaar | #1 | Nov 2008 | one-shot |
| Skeleton Warriors | | #1–4 | Apr 1995 – Jul 1995 | limited series |
| Skrull Kill Krew | vol. 1 | #1–5 | Sep 1995 – Jan 1996 | limited series |
| vol. 2 | #1–5 | Jun – Dec 2009 | limited series |
| Skrulls! | | #1 | Jul 2008 | one-shot; Secret Invasion tie-in |
| Skrulls vs. Power Pack | | #1–4 | Sep – Dec 2008 | limited series |
| Skull the Slayer | | #1–8 | Aug 1975 – Nov 1976 | |
| Sky Doll | | #1–3 | May 2008 – Jul 2008 | limited series |
| Doll's Factory | #1–2 | Jan 2010 – Feb 2010 | limited series |
| Lacrima Christi Collection | #1–2 | Sep 2010 – Oct 2010 | limited series |
| Space Ship | #1–2 | Jul 2010 – Aug 2010 | limited series |
| Slapstick | vol. 1 | #1–4 | Nov 1992 – Feb 1993 | limited series |
| vol. 2 | #1–6 | Feb – Jul 2017 | limited series |
| Sledge Hammer! | | #1–2 | Feb – Mar 1988 | based on the TV series |
| Sleepwalker | | #1–33 | Jun 1991 – Feb 1994 | |
| Holiday Special #1 | Jan 1993 | |
| Slingers | | #1–12 | Dec 1998 – Nov 1998 | |
| Smurfs | | #1–3 | Dec 1982 – Feb 1983 | |
| Snow White | | #1 | Jan 1995 | one-shot; also known as Walt Disney's Snow White and the Seven Dwarfs |
| Solarman | | #1–2 | Jan 1989 – May 1990 | |
| Soldier X | | #1–12 | Sep 2002 – Aug 2003 | |
| Solo | vol. 1 | #1–4 | Sep – Dec 1994 | limited series |
| vol. 2 | #1–5 | Dec 2016 – Apr 2017 | limited series |
| Solo: A Star Wars Story Adaptation | | #1–7 | Dec 2018 – Jun 2019 | limited series; film tie-in |
| Solo Avengers | | #1–20 | Dec 1987 – Jul 1999 | continues as Avengers Spotlight |
| Solomon Kane | | #1–6 | Sep 1985 – Jul 1986 | limited series |
| Son of Hulk | | #13–17 | Sep 2009 – Jan 2010 | continues from Skaar: Son of Hulk |
| Son of M | | #1–6 | Feb – Jul 2006 | limited series |
| Son of Satan | | #1–8 | Dec 1975 – Feb 1977 | |
| Son of Yuppies from Hell | | | 1990 | one-shot |
| Soviet Super-Soldiers | | #1 | Nov 1992 | one-shot |
| Space: Punisher | | #1–4 | Sep – Dec 2012 | limited series |
| Spaceknights | | #1–5 | Oct 2000 – Feb 2001 | limited series |
| Special Marvel Edition | | #1–16 | Jan 1971 – Feb 1974 | continues with Master of Kung Fu vol. 1 |
| Spectacular Scarlet Spider | | #1–2 | Nov – Dec 1995 | limited series |
| Spectacular Spider-Girl | | #1–4 | Jul – Oct 2010 | limited series |
| Spectacular Spider-Man | vol. 1 | #1–263 | Dec 1976 – Nov 1998 | also known as Peter Parker, The Spectacular Spider-Man |
| Annual #1–14 | 1979 – 1994 |
| Super Special #1 | Sep 1995 |
| vol. 2 | #1–27 | Sep 2003 – Jun 2005 | |
| vol. 3 | #1000 | Jun 2011 | one-shot |
| Speedball | | #1–10 | Sep 1988 – Jun 1989 | |
| Spellbinders | | #1–6 | May – Oct 2005 | limited series |
| Spellbound | vol. 2 | #1–6 | Jan – Apr 1988 | limited series
vol 1 was published by Atlas Comics |
| Spider-Force | | #1–3 | Dec 2018 – Feb 2019 | limited series |
| Spider-Geddon | vol. 1 | #0–5 | Nov 2018 – Jan 2019 | limited series |
| Handbook | #1 | Feb 2019 | one-shot |
| Spider-Girl | vol. 1 | #0–100 | Oct 1998 – Sep 2006 | |
| 1999 | 1999 | Annual |
| vol. 2 | #1–8 | Jan – Sep 2011 | |
| The End! | #1 | Oct 2010 | one-shot |
| Spider-Girls | | #1–3 | Dec 2018 – Feb 2019 | limited series |
| Spider-Gwen | vol. 1 | #1–5 | Apr – Aug 2015 | |
| vol. 2 | #1–34 | Dec 2015 – Sep 2018 | |
| Annual #1 | 2016 | |
| Ghost-Spider | #1–10 | Dec 2018 – Sep 2019 | |
| Spider-Ham 25th Anniversary Special | | #1 | Aug 2010 | one-shot |
| Spider-Island | | #1–5 | Sep – Dec 2015 | limited series |
| Cloak & Dagger | #1–3 | Oct – Dec 2011 | limited series |
| Deadly Foes | #1 | Oct 2011 | one-shot |
| Deadly Hands of Kung Fu | #1–3 | Oct – Dec 2011 | limited series |
| Emergence of Evil - Jackal & Hobgoblin | #1 | Oct 2011 | one-shot |
| Heroes for Hire | #1 | Dec 2011 | one-shot |
| I Love New York City | #1 | Nov 2011 | one-shot |
| Spider-Woman | #1 | Nov 2011 | one-shot |
| Spotlight | | Sep 2011 | one-shot |
| The Amazing Spider-Girl | #1–3 | Oct – Dec 2011 | limited series |
| The Avengers | #1 | Nov 2011 | one-shot |
| Spider-Man | vol. 1 | #1–98
-1 | Aug 1990 – Dec 1998 | also known as Peter Parker, Spider-Man |
| '97, '98 | 1997 – 1998 | Annuals |
| Holiday Special 1995 | 1995 | |
| Super Special #1 | Jul 1995 | |
| vol. 2 | #1–21
234–240 | April 2016 – Jul 2018 | |
| Annual | #1 | Aug 2019 | one-shot; subtitled Peter Porker, The Spectacular Spider-Ham |
| Battlebook: Streets of Fire | | 1998 | one-shot |
| Black and Blue and Read All Over | #1 | Nov 2006 | one-shot |
| Blue | #1–6 | Jul 2002 – Apr 2003 | limited series |
| Brand New Day Yearbook | #1 | 2008 | one-shot |
| Breakout | #1–5 | Jun – Oct 2005 | limited series |
| Carnage | | Jun 1993 | one-shot |
| Chapter One | #1–12
0 | Dec 1998 – Oct 1999 | limited series |
| Collectors' Preview | #1 | Dec 1994 | one-shot |
| Dead Man's Hand | #1 | Apr 1997 | one-shot |
| Death and Destiny | #1–3 | Aug – Oct 2000 | limited series |
| Enter the Spider-Verse | #1 | Jan 2019 | one-shot |
| Fear Itself | #1 | Mar 2009 | one-shot; also known as The Amazing Spider-Man: Fear Itself |
| Fever | #1–3 | Jun – Aug 2010 | limited series |
| Friends and Enemies | #1–4 | Jan – Apr 1995 | limited series |
| Funeral for an Octopus | #1–3 | Mar – May 1995 | limited series |
| Get Kraven | #1–6 | Aug 2002 – Jan 2003 | limited series |
| Giant-Size vol. 1 | #1–6 | 1974 – 1975 | |
| Giant-Size vol. 2 | #1 | Jul 2014 | one-shot |
| Grim Hunt -- The Kraven Saga | | May 2010 | one-shot |
| Hobgoblin Lives | #1–3 | Jan – Apr 1997 | limited series |
| House of M | #1–5 | Aug – Dec 2005 | limited series |
| India | #1–4 | Jan – Apr 2005 | limited series |
| Legacy of Evil | #1 | Jun 1996 | one-shot |
| Legend of the Spider-Clan | #1–5 | 2002 – 2003 | limited series |
| Life Story | #1–6 | May 2019 – Oct 2019 | limited series |
| Lifeline | #1–3 | Apr – Jun 2001 | limited series |
| Made Men | #1 | Aug 1998 | one-shot |
| Master Plan | #1 | Sep 2017 | one-shot |
| Maximum Clonage | Alpha #1 | Aug 1995 | one-shot |
| Omega #1 | Aug 1995 | one-shot |
| Origin of the Hunter | #1 | Jun 2010 | one-shot |
| Power of Terror | #1–4 | Jan – Apr 1995 | limited series |
| Quality of Life | #1–4 | Jul – Oct 2002 | limited series |
| Redemption | #1–4 | Sep – Dec 1996 | limited series |
| Reign | #1–4 | 2007 | limited series |
| Reptilian Rage | #1 | Aug 2019 | one-shot |
| Revenge of the Green Goblin | #1–3 | Oct – Dec 2000 | limited series |
| Special Edition | #1 | Nov 1992 | one-shot; mail-order exclusive |
| Spectacular | #1 | Aug 2014 | one-shot |
| Sweet Charity | #1 | Aug 2002 | one-shot |
| The Arachnis Project | #1–6 | Aug 1994 – Jan 1995 | limited series |
| The Clone Journal | #1 | Mar 1995 | one-shot |
| The Final Adventure | #1–4 | Dec 1995 – Mar 1996 | limited series |
| The Jackal Files | #1 | Aug 1995 | one-shot |
| The Lost Years | #0–3 | Aug 1995 – Jan 1996 | limited series |
| The Mutant Agenda | #0–3 | Feb 1992 – May 1994 | limited series |
| The Official Movie Adaptation | #1 | Jun 2002 | one-shot, adaptation of the 2002 film |
| The Osborn Journal | #1 | Feb 1997 | one-shot |
| The Parker Years | #1 | Nov 1995 | one-shot |
| The Short Halloween | #1 | Jul 2009 | one-shot; also known as The Amazing Spider-Man: The Short Halloween |
| The Venom Agenda | #1 | Jan 1998 | one-shot |
| Unmasked | #1 | Dec 1996 | one-shot |
| Web of Doom | #1–3 | Aug – Oct 1994 | limited series |
| With Great Power... | #1–5 | Mar – Sep 2008 | limited series |
| With Great Power Comes Great Responsibility | #1–7 | Jun – Dec 2011 | |
| Spider-Man / | Black Cat: The Evil That Men Do | #1–6 | Aug 2002 – Mar 2006 | limited series, three year gap between publication of issues 3 & 4 |
| Daredevil | #1 | Oct 2002 | one-shot |
| Deadpool | #1–50 | Mar 2016 – Jul 2019 | |
| Doctor Octopus: Out of Reach | #1–5 | Jan – May 2004 | limited series |
| Doctor Octopus: Year One | #1–5 | Aug – Dec 2004 | limited series |
| Dr. Strange: The Way to Dusty Death | | 1992 | one-shot |
| Fantastic Four | #1–4 | Sep – Dec 2010 | limited series |
| Gen13 | | Nov 1996 | one-shot; co-published with Image Comics |
| Human Torch | #1–5 | Mar – Jul 2005 | limited series |
| Punisher: Family Plot | #1–2 | Feb 1996 | limited series |
| Red Sonja | #1–5 | Oct 2007 – Feb 2008 | limited series; co-published with Dynamite Entertainment |
| Spider-Man & | Araña Special: The Hunter Revealed | #1 | May 2006 | one-shot |
| The Human Torch in... Bahia De Los Muertos! | #1 | May 2009 | one-shot |
| The Secret Wars | #1–4 | Jan – May 2010 | limited series |
| The X-Men | #1–6 | Feb – Jun 2015 | limited series |
| Wolverine | #1–4 | Aug – Nov 2003 | limited series |
| Spider-Man 2099 | vol. 1 | #1–46 | Nov 1992 – Aug 1996 | |
| Annual #1 | 1994 | |
| Special #1 | Nov 1995 | |
| vol. 2 | #1–12 | Sep 2014 – Jul 2015 | |
| vol. 3 | #1–25 | Dec 2015 – Sep 2017 | |
| Meets Spider-Man | | Nov 1995 | one-shot |
| Spider-Man 2 | | #1 | Aug 2004 | one-shot, movie adaptation |
| Spider-Man 3 Movie Prequel | | | Jun 2007 | one-shot, movie tie-in |
| Spider-Man Adventures | | #1–15 | Dec 1994 – Mar 1996 | Based on the 1994 TV Series |
| Spider-Man and | Batman | | Sep 1995 | one-shot; co-published with DC |
| Daredevil Special Edition | #1 | Mar 1984 | one-shot |
| Spider-Man and His Amazing Friends | #1 | Dec 1981 | One-shot
Based on the 1980s animated tv show |
| Mysterio | #1–3 | Jan – Mar 2001 | limited series; also known as Spider-Man: The Mysterio Manifesto |
| Power Pack | #1–4 | Jan – Apr 2007 | limited series |
| The Fantastic Four | #1–4 | June 2007 | limited series |
| X-Factor: Shadowgames | #1–3 | May – Jul 1994 | limited series |
| Spider-Man Classics | | #1–16 | Apr 1993 – Jul 1994 | |
| Spider-Man: The Clone Saga | | #1–6 | Nov 2009 – Apr 2010 | limited series |
| Spider-Man Fairy Tales | | #1–4 | Jul – Oct 2007 | limited series |
| Spider-Man Family | vol. 1 | | 2005 | one-shot |
| vol. 2 | #1–9 | Apr 2007 – Aug 2008 | |
| Featuring Spider-Clan | #1 | Jan 2007 | one-shot |
| Featuring Spider-Man's Amazing Friends | #1 | Oct 2006 | one-shot |
| Spider-Man Homecoming Prelude | | #1–2 | 2017 | limited series, movie tie-in |
| Spider-Man Loves Mary Jane | | #1–20 | Feb 2006 – Sep 2007 | |
| Season 2 | #1–5 | Oct 2008 – Feb 2009 | |
| Spider-Man Noir | | #1–4 | Feb – May 2009 | limited series |
| Eyes Without a Face | #1–4 | 2009 | limited series |
| Spider-Man, Punisher, Sabretooth: Designer Genes | | | 1993 | graphic novel |
| Spider-Man Saga | vol. 1 | #1–4 | Nov 1991 – Feb 1992 | limited series |
| vol. 2 | | Dec 2010 | one-shot |
| Spider-Man's Tangled Web | | #5–22 | Oct 2001 – Mar 2003 | continues from Tangled Web: The Thousand |
| Spider-Man Team-Up | vol.1 | #1–7 | Dec 1995 – Jun 1997 | |
| vol. 2 | Special #1 | May 2005 | one-shot |
| Spider-Man Universe | | #1–21 | Mar 2000 – Oct 2001 | |
| Spider-Man Unlimited | vol. 1 | #1–22 | May 1993 – Nov 1998 | |
| vol. 2 | #1–5 | Dec 1999 – Apr 2000 | based on the 1999 TV series |
| vol. 3 | #1–15 | Mar 2004 – Jul 2006 | |
| Spider-Man vs. | Dracula | #1 | Jul 1994 | one-shot |
| Punisher | #1 | Jul 2000 | one-shot |
| Vampires | #1 | Dec 2010 | one-shot |
| Wolverine | #1 | Feb 1987 | one-shot |
| Spider-Men | | #1–5 | Aug – Nov 2012 | limited series |
| II | #1–5 | Sep 2017 – Feb 2018 | limited series |
| Spider-Verse | | #1–5 | Jul – Nov 2015 | limited series |
| Spider-Verse Team-Up | | #1–3 | Jan – Mar 2015 | limited series |
| Spider-Woman | vol. 1 | #1–50 | Apr 1978 – Jun 1983 | |
| vol. 2 | #1–4 | Nov 1993 – Feb 1994 | limited series |
| vol. 3 | #1–18 | Jul 1999 – Dec 2000 | |
| vol. 4 | #1–7 | Nov 2009 – May 2010 | |
| vol. 5 | #1–10 | Jan – Oct 2015 | |
| vol. 6 | #1–17 | Jan 2016 – May 2017 | |
| Giant-Size | #1 | 2005 | one-shot |
| Origin | #1–5 | Feb – Jun 2006 | limited series |
| Spider-Women | Alpha | #1 | Jun 2016 | one-shot |
| Omega | #1 | Aug 2016 | one-shot |
| Spidey | | #1–12 | Feb 2016 – Jan 2017 | |
| Spidey and the Mini-Marvels | | #1 | May 2003 | one-shot |
| Spidey / Marrow | | #1 | Feb 2001 | one-shot |
| Spidey Super Stories | | #1–57 | Oct 1974 – Mar 1982 | |
| Spin Angels | | #1–4 | Aug 2009 – Dec 2009 | |
| Spirits of Vengeance | | #1–5 | Dec 2017 – Apr 2018 | limited series |
| Spitfire | | #1 | Sep 2010 | one-shot |
| Spitfire and the Troubleshooters | | #1–9 | Oct 1986 – Jun 1987 | continues with Codename: Spitfire |
| Spoof | | #1–5 | Oct 1970 – May 1973 | Two-year publishing gap between issues 1 and 2 |
| Spotlight | | #1–4 | Sep 1978 – May 1979 | |
| Squadron Sinister | | #1–4 | Aug 2015 – Jan 2016 | limited series |
| Squadron Supreme | vol. 1 | #1–12 | Sep 1985 – Aug 1986 | limited series |
| vol. 2 | #1–7 | May – Nov 2006 | |
| vol. 3 | #1–12 | Sep 2008 – Aug 2009 | |
| vol. 4 | #1–15 | Feb 2016 – Mar 2017 | |
| Hyperion vs. Nighthawk | #1–4 | Mar – Jun 2007 | limited series |
| New World Order | #1 | Sep 1998 | one-shot |
| Stan Lee Meets... | Dr. Doom | #1 | Dec 2006 | one-shot |
| Dr. Strange | #1 | Dec 2006 | one-shot |
| Silver Surfer | #1 | Jan 2007 | one-shot |
| Spider-Man | #1 | Nov 2006 | one-shot |
| The Thing | #1 | Dec 2006 | one-shot |
| The Stand | American Nightmares | #1–5 | May – Oct 2009 | limited series |
| Captain Trips | #1–5 | Dec 2008 – Mar 2009 | limited series |
| Hardcases | #1–5 | Aug 2010 – Jan 2011 | limited series |
| No Man's Land | #1–5 | Apr – Aug 2011 | limited series |
| Soul Survivors | #1–5 | Dec 2009 – May 2010 | limited series |
| The Night Has Come | #1–6 | Oct 2011 – Mar 2012 | limited series |
| Starblast | | #1–4 | Jan – Apr 1994 | limited series |
| Star Brand | | #1–19 | Oct 1986 – May 1989 | |
| Annual #1 | Oct 1987 | |
| Starbrand and Nightmask | | #1–6 | Feb – Jul 2016 | limited series |
| Starjammers | vol. 1 | #1–4 | Oct 1995 – Jan 1996 | limited series |
| vol. 2 | #1–6 | Sep 2004 – Jan 2005 | limited series |
| Star-Lord | vol. 1 | Special Edition #1 | Feb 1982 | one-shot |
| vol. 2 | #1–3 | Dec 1996 – Feb 1997 | limited series; titled Starlord |
| vol. 3 | #1–8 | Jan – Aug 2016 | |
| vol. 4 | #1–6 | Feb – Jun 2017 | |
| Annual #1 | 2017 | |
| Star-Lord & Kitty Pryde | | #1–3 | Sep – Nov 2015 | limited series |
| Starmasters | | #1–3 | Dec 1995 – Feb 1996 | limited series |
| Starriors | | #1–4 | Nov 1984 – Feb 1985 | limited series |
| Starr the Slayer | | #1–4 | Nov 2009 – Feb 2010 | limited series |
| Startling Stories | Banner | #1–4 | Jul – Oct 2001 | limited series |
| Fantastic Four – Unstable Molecules | #1–4 | Mar – Jun 2003 | limited series |
| The Megalomaniacal Spider-Man | #1 | Jun 2002 | one-shot |
| The Thing | #1 | 2003 | one-shot |
| The Thing – Night Falls on Yancy Street | #1–4 | Jun – Sep 2003 | limited series |
| Star Trek | | #1–18 | Apr 1980 – Feb 1982 | |
| Collector's Preview | #1–2 | Jul 1996 – Jul 1997 | limited series |
| Deep Space Nine | #1–15 | Nov 1996 – Mar 1998 | |
| Early Voyages | #1–17 | Feb 1997 – Jun 1998 | |
| First Contact | #1 | Nov 1996 | one-shot, adaptation of the movie |
| Mirror Mirror | #1 | Feb 1997 | one-shot |
| Operation Assimilation | #1 | Apr 1997 | one-shot |
| Starfleet Academy | #1–19 | Dec 1996 – Jun 1998 | |
| Telepathy War | #1 | Nov 1997 | one-shot |
| The Next Generation: Riker | #1 | Jul 1998 | one-shot |
| Untold Voyages | #1–5 | Mar – Jul 1998 | limited series |
| Voyager | #1–15 | Nov 1996 – Mar 1998 | |
| Voyager – Splashdown | #1–4 | Apr – Jul 1998 | limited series |
| Star Trek Unlimited | | #1–10 | Nov 1996 – Jul 1998 | |
| Star Trek / X-Men | | #1 | Dec 1996 | one-shot |
| 2nd Contact | #1 | May 1998 | one-shot |
| Star Wars | vol. 1 | #1–107 | Jul 1977 – Jul 1986 | |
| Annual #1–3 | 1979 – 1983 | |
| vol. 2 | #1– | Mar 2015 – present | |
| Annual #1–4 | 2016 – 2019 | |
| Beckett | #1 | Oct 2018 | one-shot |
| C-3PO | #1 | June 2016 | one-shot |
| Darth Maul | #1–5 | Apr – Sep 2017 | limited series |
| Doctor Aphra | #7– | Jul 2017 – present | continued from Doctor Aphra |
| Annual #1–2 | 2017 – 2018 | |
| Droids Unplugged | #1 | Aug 2017 | one-shot |
| Galaxy's Edge | #1–5 | Jun 2019 – Oct 2019 | limited series |
| Han Solo - Imperial Cadet | #1–5 | Jan – May 2019 | limited series |
| Lando - Double or Nothing | #1–5 | July – Sep 2018 | limited series |
| Mace Windu | #1–5 | Oct 2017 – Feb 2018 | limited series |
| Return of the Jedi | #1–4 | Oct 1983 – Jan 1984 | limited series, movie adaptation |
| Rogue One | #1–6 | Jun – Nov 2017 | limited series, movie adaptation |
| Rogue One - Cassian & K-2SO Special | #1 | Oct 2017 | one-shot |
| Tag & Bink Were Here | #1 | Jul 2018 | one-shot |
| Target Vader | #1–6 | Sep 2019 – present | limited series |
| The Force Awakens | #1–6 | Aug 2016 – Jan 2017 | limited series, movie adaptation |
| The Screaming Citadel | #1 | Jul 2017 | one-shot |
| Thrawn | #1–6 | Apr 2018 – Sep 2018 | limited series |
| TIE Fighter | #1–5 | Jun 2019 – Oct 2019 | limited series |
| Vader — Dark Visions | #1–5 | May 2019 – present | limited series |
| Vader Down | #1 | Jan 2016 | one-shot |
| Star Wars: Age of Rebellion | Boba Fett | #1 | Jul 2019 | one-shot |
| Darth Vader | #1 | Aug 2019 | one-shot |
| Grand Moff Tarkin | #1 | Jun 2019 | one-shot |
| Han Solo | #1 | Jul 2019 | one-shot |
| Jabba the Hutt | #1 | Jul 2019 | one-shot |
| Lando Calrissian | #1 | Jul 2019 | one-shot |
| Luke Skywalker | #1 | Aug 2019 | one-shot |
| Princess Leia | #1 | Jun 2019 | one-shot |
| Special | #1 | Jun 2019 | one-shot |
| Star Wars: Age of Republic | Anakin Skywalker | #1 | Apr 2019 | one-shot |
| Count Dooku | #1 | Apr 2019 | one-shot |
| Darth Maul | #1 | Feb 2019 | one-shot |
| General Grievous | #1 | May 2019 | one-shot |
| Jango Fett | #1 | Mar 2019 | one-shot |
| Obi-Wan Kenobi | #1 | Mar 2019 | one-shot |
| Padmé Amidala | #1 | May 2019 | one-shot |
| Qui-Gon Jinn | #1 | Feb 2019 | one-shot |
| Special | #1 | Mar 2019 | one-shot |
| Star Wars: Age of Resistance | Captain Phasma | #1 | Sep 2019 | one-shot |
| Finn | #1 | Sep 2019 | one-shot |
| General Hux | #1 | Oct 2019 | one-shot |
| Poe Dameron | #1 | Oct 2019 | one-shot |
| Special | #1 | Sep 2019 | one-shot |
| Star Wars: The Last Jedi | | #1–6 | Jul – Dec 2018 | limited series; movie adaptation |
| DJ - Most Wanted | #1 | Mar 2018 | one-shot |
| The Storms of Crait | #1 | Feb 2018 | one-shot |
| Steeltown Rockers | | #1–6 | Apr 1990 – Sep 1990 | limited series |
| Stephen King's N. | | #1–4 | May 2010 – Aug 2010 | limited series |
| Steve Rogers: Super-Soldier | | #1–4 | Sep – Dec 2010 | limited series |
| Annual #1 | Jun 2011 | |
| Stoker's Dracula | | #1–4 | Oct 2004 – May 2005 | limited series |
| Storm | vol. 1 | #1–4 | Feb – May 1996 | limited series |
| vol. 2 | #1–6 | Apr – Sep 2006 | limited series |
| vol. 3 | #1–11 | Sep 2014 – Jul 2015 | |
| Battlebook: Streets of Fire | | 1998 | one-shot |
| Stormbreaker: The Saga of Beta Ray Bill | | #1–6 | Mar – Aug 2005 | limited series |
| Strange | vol. 1 | #1–6 | Nov 2004 – Jul 2005 | limited series |
| vol. 2 | #1–4 | Jan – Apr 2010 | limited series |
| Strange Days | | #1 | Dec 1995 | one-shot, film adaptation |
| Strange Tales | vol. 1 | #86–168 | Jul 1961 – May 1968 | previous issues published by Atlas Comics
continues with Doctor Strange vol. 1 |
| Annual #1–2 | 1962 – 1963 | |
| vol. 2 | #169–188 | Sep 1973 – Nov 1976 | numbering picks up where vol. 1 left off |
| vol. 3 | #1–19 | Apr 1987 – Oct 1988 | |
| vol. 4 | #1 | Nov 1994 | one-shot |
| vol. 5 | #1–2 | Sep – Oct 1998 | limited series |
| vol. 6 | #1–3 | Nov 2009 – Jan 2010 | limited series |
| Dark Corners | #1 | May 1998 | one-shot |
| Strange Tales II | | #1–3 | Dec 2010 – Feb 2011 | limited series |
| Street Poet Ray | | #1–4 | 1990 | limited series |
| Strikeforce: Morituri | | #1–31 | Dec 1986 – Jul 1989 | |
| Electric Undertow | #1–5 | Dec 1989 – Mar 1990 | limited series |
| Strong Guy Reborn | | #1 | Sep 1997 | one-shot |
| Stryfe's Strike File | | #1 | Jan 1993 | one-shot |
| Sub-Mariner | vol. 2 | #1–72 | May 1968 – Sep 1974 | vol. 1 was published by Atlas Comics |
| Special #1–2 | Jan 1971 – Jan 1972 | |
| vol. 3 | #1–6 | Aug 2007 – Jan 2008 | limited series |
| The Depths | #1–5 | Nov 2008 – May 2009 | limited series |
| Sub-Mariner Comics 70th Anniversary Special | | #1 | Jun 2009 | one-shot based on Timely Comics series |
| Suburban Jersey Ninja She-Devils | | #1 | Jan 1992 | one-shot |
| Sunfire & Big Hero Six | | #1–3 | Sep – Nov 1998 | limited series |
| Super-Heroes | | Giant-Size #1 | Jun 1974 | one-shot |
| Superior Carnage | | #1–5 | Sep 2013 – Jan 2014 | limited series |
| Annual #1 | Apr 2014 | |
| The Superior Foes of Spider-Man | | #1–17 | Sep 2013 – Jan 2015 | |
| Superior Iron Man | | #1–9 | Jan – Aug 2015 | |
| The Superior Octopus | | #1 | Dec 2018 | one-shot |
| Superior Spider-Man | vol. 1 | #1–33 | Mar 2013 – Nov 2014 | |
| Annual #1–2 | Jan – May 2014 | |
| vol. 2 | #1– | Feb 2019 – present | |
| Superior Spider-Man Team-Up | | #1–12 | Sep 2013 – Jun 2014 | |
| Special #1 | Dec 2013 | |
| Superman/Fantastic Four | | | Apr 1999 | one-shot; co-published with DC |
| Superman vs. The Amazing Spider-Man | | | 1976 | one-shot; co-published with DC |
| The Supernaturals | | #1–4 | Dec 1998 | limited series |
| Supernatural Thrillers | | #1–15 | Dec 1972 – Oct 1975 | |
| Super Soldiers | | #1–8 | Apr – Nov 1993 | |
| Super Stars | | Giant-Size #1 | May 1974 | one-shot |
| Super-Villain Team-Up | vol. 1 | #1–17 | Aug 1975 – Jun 1980 | |
| Giant-Size #1–2 | Mar – Jun 1975 | |
| vol. 2 | #1–5 | Sep 2007 – Jan 2008 | limited series; also known as Modok's 11 |
| Supreme Power | vol. 1 | #1–18 | Oct 2003 – Oct 2005 | |
| vol. 2 | #1–4 | Aug 2011 – Nov 2011 | limited series |
| Hyperion | #1–5 | Nov 2005 – Mar 2006 | limited series |
| Nighthawk | #1–6 | Nov 2005 – Apr 2006 | limited series |
| Survive! | | #1 | May 2014 | one-shot |
| Sweet XVI | vol. 1 | #1–6 | May 1991 – Oct 1991 | |
| Back to School Special | #1 | Nov 1992 | one-shot |
| S.W.O.R.D. | | #1–5 | Jan – May 2010 | |
| Sword Master | | #1– | Sep 2019 – present | |
| Symbiote Spider-Man | | #1–5 | Jun 2019 – Oct 2019 | limited series |
