List of side effects of buspirone

Side effects of buspirone by incidence include: ^{[1] [2] [3] [4]}

Very common (>10% incidence)

• Dizziness/lightheadedness
• Headache
• Somnolence (sleepiness)

Common (1–10% incidence)

• Nervousness
• Insomnia
• Sleep disorder
• Disturbance in attention
• Depression
• Confusional state
• Anger
• Tachycardia (fast heart rate)
• Chest pain
• Sinusitis (nasal congestion)
• Pharyngolaryngeal pain
• Paraesthesia (tingling skin)
• Blurred vision
• Abnormal coordination
• Tremor
• Cold sweat
• Rash
• Nausea
• Abdominal pain
• Dry mouth
• Diarrhea
• Constipation
• Vomiting
• Fatigue
• Musculoskeletal pain

Uncommon (0.1–1%)

• Syncope
• Hypotension
• Hypertension
• Redness and itching of the eyes
• Altered taste
• Conjunctivitis
• Flatulence
• Anorexia
• Increased appetite
• Salivation
• Rectal bleeding
• Urinary frequency
• Urinary hesitancy
• Menstrual irregularity or spotting
• Dysuria
• Muscle cramps
• Muscle spasms
• Muscle rigidity/stiffness
• Involuntary movements
• Shortness of breath
• Chest congestion
• Changes in libido
• Oedema
• Pruritus
• Flushing
• Easy bruising
• Dry skin
• Facial oedema
• Mild increases in hepatic aminotransferases (AST, ALT)
• Weight gain
• Fever
• Roaring sensation in the head
• Weight loss
• Malaise
• Depersonalisation
• Noise intolerance
• Euphoria
• Akathisia
• Fearfulness
• Loss of interest
• Dissociative reaction

Rare (<0.1% incidence)

• Cerebrovascular accident (stroke)
• Myocardial infarction (heart attack)
• Cardiomyopathy
• Congestive heart failure
• Bradycardia
• Dysphoria
• Hallucinations
• Feelings of claustrophobia
• Cold intolerance
• Stupor
• Seizures
• Slurred speech
• Extrapyramidal symptoms including dyskinesias (acute & delayed)
• Dystonic reactions
• Cogwheel rigidity
• Emotional lability
• Psychosis
• Suicidal ideation
• Ataxias
• Transient difficulty with recall
• Serotonin syndrome
• Parkinsonism
• Restless leg syndrome
• Restlessness
• Eye pain
• Altered sense of smell
• Photophobia
• Pressure on eyes
• Inner ear abnormality
• Tunnel vision
• Galactorrhoea
• Irritable bowel syndrome
• Burning of the tongue
• Arthralgias
• Amenorrhoea (cessation of menstrual cycles)
• Enuresis
• Nocturia
• Pelvic inflammatory disease
• Urinary retention
• Hyperventilation
• Epistaxis
• Delayed ejaculation
• Impotence
• Acne
• Hair loss
• Blisters
• Thinning of nails
• Allergic reactions including urticaria, ecchymosis, angioedema
• Eosinophilia
• Leucopenia
• Thrombocytopaenia
• Excessive use of alcohol
• Bleeding disturbance
• Loss of voice
• Hiccups
• Thyroid abnormality

References

1. "buspirone (Rx) - BuSpar, Buspirex, more." Medscape Reference. WebMD. Retrieved 14 November 2013.
2. "BUSPIRONE HCL (buspirone hydrochloride) tablet [Watson Laboratories, Inc.]". DailyMed. Watson Laboratories, Inc. July 2013. Retrieved 14 November 2013.
3. "BUSPAR® (buspirone hydrochloride) Tablets 5 mg & 10 mg PRODUCT INFORMATION" (PDF). TGA eBusiness Services. Aspen Pharma Pty Ltd. January 2010. Retrieved 14 November 2013.
4. "Buspirone 10mg Tablets". electronic Medicines Compendium. Actavis UK Ltd. 10 September 2012. Retrieved 14 November 2013.