Lulu Qian

Last updated
Lulu Qian
Born
Alma mater Nanjing Railway University
Shanghai Jiao Tong University
Scientific career
Institutions California Institute of Technology
Academic advisors Erik Winfree

Lulu Qian is a Chinese-American biochemist who is a professor at the California Institute of Technology. Her research uses DNA-like molecules to build artificial machines.

Contents

Early life and education

Qian is from China. She completed her bachelor's degree in biomedical engineering at Southeast University in Nanjing. [1] Qian moved to Shanghai for her doctoral research, where she worked at Shanghai Jiao Tong University on biochemistry. [2] She then moved to the California Institute of Technology as a postdoctoral fellow. [3] At Caltech, she worked alongside Erik Winfree on biochemical circuits. She used a reversible strand displacement process to create a simple DNA-based building block for a biochemical logic circuit. [4]

Research and career

Qian joined the faculty at Caltech in 2013. She was promoted to professor in 2019. [5] Her research considers molecular robotics and the self-assembly of nanostructures from DNA. These molecular robots can explore biologically relevant surfaces at the nanoscale, picking up molecules and transporting them to specific locations. [6] In 2011, she created the world's largest DNA circuit, which included over seventy DNA molecules. [7]

Qian has also created complex DNA origami. [8] She created two-dimensional images from DNA origami tiles. [8] She used DNA to create an artificial neural network. [9] The network consisted of a DNA gate architecture that can be scaled up into multi-layer circuits. [9] [10]

Awards and honors

Selected publications

References

  1. "Lulu Qian | Caltech Directory". directory.caltech.edu. Retrieved 2023-03-05.
  2. "Introducing ISNSCE Vice President Lulu Qian". ISNSCE. 2021-12-11. Retrieved 2023-03-05.
  3. "Programming DNA for Molecular Robots: An Interview with Lulu Qian – Pasadena Now". www.pasadenanow.com. Retrieved 2023-03-05.
  4. Qian, Lulu; Winfree, Erik (2011-06-03). "Scaling Up Digital Circuit Computation with DNA Strand Displacement Cascades" . Science. 332 (6034): 1196–1201. Bibcode:2011Sci...332.1196Q. doi:10.1126/science.1200520. ISSN   0036-8075. PMID   21636773. S2CID   10053541.
  5. "Lulu Qian's CV" (PDF).
  6. Major, Mario L. (2017-09-16). "Scientists Build DNA Robots That Could One Day Deliver Medicine Inside Your Body". interestingengineering.com. Retrieved 2023-03-04.
  7. "Caltech researchers build largest biochemical circuit out of small synthetic DNA molecules". EurekAlert!. Retrieved 2023-03-04.
  8. 1 2 Andy Extance2017-12-07T14:30:00+00:00. "DNA origami makes it big". Chemistry World. Retrieved 2023-03-04.{{cite web}}: CS1 maint: numeric names: authors list (link)
  9. 1 2 Qian, Lulu; Winfree, Erik; Bruck, Jehoshua (July 2011). "Neural network computation with DNA strand displacement cascades" . Nature. 475 (7356): 368–372. doi:10.1038/nature10262. ISSN   1476-4687. PMID   21776082. S2CID   1735584.
  10. Mehar, Pranjal (2018-07-10). "Scientists created AI from DNA". Tech Explorist. Retrieved 2023-03-04.
  11. "Foresight Institute Awards 2019 Feynman Prizes in Nanotechnology to Qian, Galli; awards presented by Nobelist, Sir Fraser Stoddart". PRWeb. Retrieved 2023-03-04.
  12. "Two Professors Receive Caltech's Highest Honors for Teaching and Mentorship". California Institute of Technology. 2023-02-21. Retrieved 2023-03-04.