Abbreviation | HNR |
---|---|
Formation | 1998 |
Dissolved | 2018 |
Type | Research institute |
Legal status | Government agency |
Purpose | Human nutrition research in the UK |
Headquarters | Elsie Widdowson Laboratory |
Location |
|
Coordinates | 52°10′57″N0°10′51″E / 52.18250°N 0.18083°E |
Region served | UK |
Director | Dr Ann Prentice |
Parent organization | Medical Research Council |
Affiliations | School of Clinical Medicine, University of Cambridge, Food Standards Agency |
Staff | c. 100 nutrition scientists |
Website | HNR |
MRC Human Nutrition Research was the largest research institute in the UK for human nutrition, and was based in Cambridge.
In 1998 MRC Human Nutrition Research (HNR) was formed as a result of the restructuring of the Dunn Human Nutrition Unit following the resignation of Professor Roger Whitehead. [1] The Medical Research Council (MRC), founded in 1913, had previously had a Human Nutrition Research Unit at the end of the Second World War; this was founded and directed by BS Platt, and was interested in serious nutritional deficiencies in children, that would cause significantly premature death. HNR was formed in order to continue to advance the MRC's portfolio of strategic and applied nutrition research. In 2016, following restructuring and refocusing of its research interests HNR was renamed MRC Elsie Widdowson Laboratory (MRC EWL).
In December 2018 MRC EWL closed.
The mission of HNR was to conduct nutrition research and surveillance to improve the health of the population with a focus on obesity and metabolic risk, musculoskeletal health, intestinal health and nutritional inequalities. [1]
HNR's four objectives [1] were to:
HNR was based at Peterhouse Technology Park, in south-east Cambridge, on the South Cambridgeshire-Cambridge boundary, round the corner from Fulbourn Hospital. ARM Holdings have their headquarters on the same site.
It was divided into three main research departments and a support department:
These departments housed research groups concerned with:
HNR also had a library which housed an important collection of historically significant research documents.
HNR conducted nutrition research and surveillance to improve the health of the population with a focus on obesity and metabolic risk, musculoskeletal health, intestinal health and nutritional inequalities.
In November 1999 HNR scientists discovered that children in the early 1950s, despite food rationing, had healthier diets than children today. They had a greater intake of calcium, from drinking more milk, and of iron, as they ate more red meat than poultry and iron containing dark green vegetables such as broccoli and kale. In the early 1950s, no children would have eaten pasta, but 50% of children in the 1990s did. However children in the 1950s were faced with more incurable illnesses, prevented today by vaccination.
In September 2002, HNR scientists proved a link between diabetes and being overweight. They found that people who had lost 9 lb in weight had reduced the chances of having diabetes by 58%.
In 2007, a study was conducted to research the effect of negative weight stigmas on patients. The conclusion was that in several cases, the belief in the negative weight stigmas led to overeating and bad health habits in patients who were studies. More details can be found in the official report listed under references.
HNR participated in the National Diet and Nutrition Survey and the MRC's National Survey of Health and Development, [2] which showed insights such as approximately five per cent of the UK's population are vegetarian.
Dieting is the practice of eating food in a regulated way to decrease, maintain, or increase body weight, or to prevent and treat diseases such as diabetes and obesity. As weight loss depends on calorie intake, different kinds of calorie-reduced diets, such as those emphasising particular macronutrients, have been shown to be no more effective than one another. As weight regain is common, diet success is best predicted by long-term adherence. Regardless, the outcome of a diet can vary widely depending on the individual.
Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL).
Abdominal obesity, also known as central obesity and truncal obesity, is the human condition of an excessive concentration of visceral fat around the stomach and abdomen to such an extent that it is likely to harm its bearer's health. Abdominal obesity has been strongly linked to cardiovascular disease, Alzheimer's disease, and other metabolic and vascular diseases.
Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it can potentially have negative affects on health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over 30 kg/m2; the range 25–30 kg/m2 is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis.
Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, by a mean loss of fluid, body fat, or lean mass. Weight loss can either occur unintentionally because of malnourishment or an underlying disease, or from a conscious effort to improve an actual or perceived overweight or obese state. "Unexplained" weight loss that is not caused by reduction in calorific intake or increase in exercise is called cachexia and may be a symptom of a serious medical condition.
Low-carbohydrate diets restrict carbohydrate consumption relative to the average diet. Foods high in carbohydrates are limited, and replaced with foods containing a higher percentage of fat and protein, as well as low carbohydrate foods.
Weight gain is an increase in body weight. This can involve an increase in muscle mass, fat deposits, excess fluids such as water or other factors. Weight gain can be a symptom of a serious medical condition.
A healthy diet is a diet that maintains or improves overall health. A healthy diet provides the body with essential nutrition: fluid, macronutrients such as protein, micronutrients such as vitamins, and adequate fibre and food energy.
Nutritional genomics, also known as nutrigenomics, is a science studying the relationship between human genome, human nutrition and health. People in the field work toward developing an understanding of how the whole body responds to a food via systems biology, as well as single gene/single food compound relationships. Nutritional genomics or Nutrigenomics is the relation between food and inherited genes, it was first expressed in 2001.
A diabetic diet is a diet that is used by people with diabetes mellitus or high blood sugar to minimize symptoms and dangerous complications of long-term elevations in blood sugar.
Bariatric surgery is a medical term for surgical procedures used to manage obesity and obesity-related conditions. Long term weight loss with bariatric surgery may be achieved through alteration of gut hormones, physical reduction of stomach size, reduction of nutrient absorption, or a combination of these. Standard of care procedures include Roux en-Y bypass, sleeve gastrectomy, and biliopancreatic diversion with duodenal switch, from which weight loss is largely achieved by altering gut hormone levels responsible for hunger and satiety, leading to a new hormonal weight set point.
John Yudkin FRSC was a British physiologist and nutritionist, and the founding Professor of the Department of Nutrition at Queen Elizabeth College, London.
Intermittent fasting is any of various meal timing schedules that cycle between voluntary fasting and non-fasting over a given period. Methods of intermittent fasting include alternate-day fasting, periodic fasting such as the 5:2 diet, and daily time-restricted eating (TRE).
Diet plays an important role in the genesis of obesity. Personal choices, food advertising, social customs and cultural influences, as well as food availability and pricing all play a role in determining what and how much an individual eats.
Weight management refers to behaviors, techniques, and physiological processes that contribute to a person's ability to attain and maintain a healthy weight. Most weight management techniques encompass long-term lifestyle strategies that promote healthy eating and daily physical activity. Moreover, weight management involves developing meaningful ways to track weight over time and to identify ideal body weights for different individuals.
Obesity in the Middle East and North Africa is a notable health issue. Out of the fifteen fattest nations in the world as of 2014, 5 were located in the Middle East and North Africa region.
A sweetened beverage is any beverage with added sugar. It has been described as "liquid candy". Consumption of sweetened beverages has been linked to weight gain, obesity, and associated health risks. According to the CDC, consumption of sweetened beverages is also associated with unhealthy behaviors like smoking, not getting enough sleep and exercise, and eating fast food often and not enough fruits regularly.
The Centres de Recherche en Nutrition Humaine or CRNHs is a network of human nutrition research centres in France. Their goal is to improve the knowledge on the functional properties of food, metabolism, and human physiology, ranging from basic research to the study of behaviours and their impact on health. France has four CRNHs which share common tools and complementary scientific skills that allow them to develop multi-center programs using their platforms and specific skills.
Pure, White and Deadly is a 1972 book by John Yudkin, a British nutritionist and former Chair of Nutrition at Queen Elizabeth College, London. Published in New York, it was the first publication by a scientist to anticipate the adverse health effects, especially in relation to obesity and heart disease, of the public's increased sugar consumption. At the time of publication, Yudkin sat on the advisory panel of the British Department of Health's Committee on the Medical Aspects of Food and Nutrition Policy (COMA). He stated his intention in writing the book in the last paragraph of the first chapter: "I hope that when you have read this book I shall have convinced you that sugar is really dangerous."
Lisa Anne Te Morenga is a New Zealand Maori academic, and is a full professor at the University of Otago. Her research focuses on nutrition and Māori health, especially in relation to dietary interventions to prevent metabolic disease.