Abbreviation | HNR |
---|---|
Formation | 1998 |
Dissolved | 2018 |
Type | Research institute |
Legal status | Government agency |
Purpose | Human nutrition research in the UK |
Headquarters | Elsie Widdowson Laboratory |
Location |
|
Coordinates | 52°10′57″N0°10′51″E / 52.18250°N 0.18083°E |
Region served | UK |
Director | Dr Ann Prentice |
Parent organization | Medical Research Council |
Affiliations | School of Clinical Medicine, University of Cambridge, Food Standards Agency |
Staff | c. 100 nutrition scientists |
Website | HNR |
MRC Human Nutrition Research was the largest research institute in the UK for human nutrition, and was based in Cambridge.
In 1998 MRC Human Nutrition Research (HNR) was formed as a result of the restructuring of the Dunn Human Nutrition Unit following the resignation of Professor Roger Whitehead. [1] The Medical Research Council (MRC), founded in 1913, had previously had a Human Nutrition Research Unit at the end of the Second World War; this was founded and directed by BS Platt, and was interested in serious nutritional deficiencies in children, that would cause significantly premature death. HNR was formed in order to continue to advance the MRC's portfolio of strategic and applied nutrition research. In 2016, following restructuring and refocusing of its research interests HNR was renamed MRC Elsie Widdowson Laboratory (MRC EWL).
In December 2018 MRC EWL closed.
The mission of HNR was to conduct nutrition research and surveillance to improve the health of the population with a focus on obesity and metabolic risk, musculoskeletal health, intestinal health and nutritional inequalities. [1]
HNR's four objectives [1] were to:
HNR was based at Peterhouse Technology Park, in south-east Cambridge, on the South Cambridgeshire-Cambridge boundary, round the corner from Fulbourn Hospital. ARM Holdings have their headquarters on the same site.
It was divided into three main research departments and a support department:
These departments housed research groups concerned with:
HNR also had a library which housed an important collection of historically significant research documents.
HNR conducted nutrition research and surveillance to improve the health of the population with a focus on obesity and metabolic risk, musculoskeletal health, intestinal health and nutritional inequalities.
In November 1999 HNR scientists discovered that children in the early 1950s, despite food rationing, had healthier diets than children today. They had a greater intake of calcium, from drinking more milk, and of iron, as they ate more red meat than poultry and iron containing dark green vegetables such as broccoli and kale. In the early 1950s, no children would have eaten pasta, but 50% of children in the 1990s did. However children in the 1950s were faced with more incurable illnesses, prevented today by vaccination.
In September 2002, HNR scientists proved a link between diabetes and being overweight. They found that people who had lost 9 lb in weight had reduced the chances of having diabetes by 58%.
In 2007, a study was conducted to research the effect of negative weight stigmas on patients. The conclusion was that in several cases, the belief in the negative weight stigmas led to overeating and bad health habits in patients who were studies. More details can be found in the official report listed under references.
HNR participated in the National Diet and Nutrition Survey and the MRC's National Survey of Health and Development, [2] which showed insights such as approximately five per cent of the UK's population are vegetarian.
Dieting is the practice of eating food in a regulated way to decrease, maintain, or increase body weight, or to prevent and treat diseases such as diabetes and obesity. As weight loss depends on calorie intake, different kinds of calorie-reduced diets, such as those emphasising particular macronutrients, have been shown to be no more effective than one another. As weight regain is common, diet success is best predicted by long-term adherence. Regardless, the outcome of a diet can vary widely depending on the individual.
Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL).
Abdominal obesity, also known as central obesity and truncal obesity, is the human condition of an excessive concentration of visceral fat around the stomach and abdomen to such an extent that it is likely to harm its bearer's health. Abdominal obesity has been strongly linked to cardiovascular disease, Alzheimer's disease, and other metabolic and vascular diseases.
Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it can potentially have negative effects on health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over 30 kg/m2; the range 25–30 kg/m2 is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis.
Human nutrition deals with the provision of essential nutrients in food that are necessary to support human life and good health. Poor nutrition is a chronic problem often linked to poverty, food security, or a poor understanding of nutritional requirements. Malnutrition and its consequences are large contributors to deaths, physical deformities, and disabilities worldwide. Good nutrition is necessary for children to grow physically and mentally, and for normal human biological development.
Low-carbohydrate diets restrict carbohydrate consumption relative to the average diet. Foods high in carbohydrates are limited, and replaced with foods containing a higher percentage of fat and protein, as well as low carbohydrate foods.
Weight gain is an increase in body weight. This can involve an increase in muscle mass, fat deposits, excess fluids such as water or other factors. Weight gain can be a symptom of a serious medical condition.
Diseases of affluence, previously called diseases of rich people, is a term sometimes given to selected diseases and other health conditions which are commonly thought to be a result of increasing wealth in a society. Also referred to as the "Western disease" paradigm, these diseases are in contrast to "diseases of poverty", which largely result from and contribute to human impoverishment. These diseases of affluence have vastly increased in prevalence since the end of World War II.
A healthy diet is a diet that maintains or improves overall health. A healthy diet provides the body with essential nutrition: fluid, macronutrients such as protein, micronutrients such as vitamins, and adequate fibre and food energy.
Nutritional genomics, also known as nutrigenomics, is a science studying the relationship between human genome, human nutrition and health. People in the field work toward developing an understanding of how the whole body responds to a food via systems biology, as well as single gene/single food compound relationships. Nutritional genomics or Nutrigenomics is the relation between food and inherited genes, it was first expressed in 2001.
A diabetic diet is a diet that is used by people with diabetes mellitus or high blood sugar to minimize symptoms and dangerous complications of long-term elevations in blood sugar.
Bariatric surgery is a surgical procedure used to manage obesity and obesity-related conditions. Long term weight loss with bariatric surgery may be achieved through alteration of gut hormones, physical reduction of stomach size, reduction of nutrient absorption, or a combination of these. Standard of care procedures include Roux en-Y bypass, sleeve gastrectomy, and biliopancreatic diversion with duodenal switch, from which weight loss is largely achieved by altering gut hormone levels responsible for hunger and satiety, leading to a new hormonal weight set point.
John Yudkin FRSC was a British physiologist and nutritionist, and the founding Professor of the Department of Nutrition at Queen Elizabeth College, London.
Intermittent fasting is any of various meal timing schedules that cycle between voluntary fasting and non-fasting over a given period. Methods of intermittent fasting include alternate-day fasting, periodic fasting, such as the 5:2 diet, and daily time-restricted eating.
Diet plays an important role in the genesis of obesity. Personal choices, food advertising, social customs and cultural influences, as well as food availability and pricing all play a role in determining what and how much an individual eats.
Weight management refers to behaviors, techniques, and physiological processes that contribute to a person's ability to attain and maintain a healthy weight. Most weight management techniques encompass long-term lifestyle strategies that promote healthy eating and daily physical activity. Moreover, weight management involves developing meaningful ways to track weight over time and to identify the ideal body weights for different individuals.
Obesity in the Middle East and North Africa is a notable health issue. Out of the 15 fattest nations in the world as of 2014, according to the World Health Organization (WHO), five were located in the Middle East and North Africa region.
Management of obesity can include lifestyle changes, medications, or surgery. Although many studies have sought effective interventions, there is currently no evidence-based, well-defined, and efficient intervention to prevent obesity.
Sugar-sweetened beverages (SSB) are beverages with added sugar. They have been described as "liquid candy". Added sugars include brown sugar, corn sweetener, corn syrup, dextrose, fructose, high fructose corn syrup, honey, invert sugar, lactose, malt syrup, maltose, molasses, raw sugar, sucrose, trehalose, and turbinado sugar. Naturally occurring sugars, such as those in fruit or milk, are not considered to be added sugars. Free sugars include monosaccharides and disaccharides added to foods and beverages by the manufacturer, cook or consumer, and sugars naturally present in honey, syrups, fruit juices and fruit juice concentrates.
Preventive Nutrition is a branch of nutrition science with the goal of preventing, delaying, and/or reducing the impacts of disease and disease-related complications. It is concerned with a high level of personal well-being, disease prevention, and diagnosis of recurring health problems or symptoms of discomfort which are often precursors to health issues. The overweight and obese population numbers have increased over the last 40 years and numerous chronic diseases are associated with obesity. Preventive nutrition may assist in prolonging the onset of non-communicable diseases and may allow adults to experience more "healthy living years." There are various ways of educating the public about preventive nutrition. Information regarding preventive nutrition is often communicated through public health forums, government programs and policies, or nutritional education. For example, in the United States, preventive nutrition is taught to the public through the use of the food pyramid or MyPlate initiatives.