MRPS2

Last updated
MRPS2
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MRPS2 , MRP-S2, S2mt, CGI-91, mitochondrial ribosomal protein S2, COXPD36
External IDs OMIM: 611971 MGI: 2153089 HomoloGene: 99837 GeneCards: MRPS2
Gene location (Human)
Ideogram human chromosome 9.svg
Chr. Chromosome 9 (human) [1]
Human chromosome 9 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 9q34.3Start135,499,984 bp [1]
End135,504,673 bp [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016034
NM_001371401

NM_001166031
NM_080452

RefSeq (protein)

NP_057118

NP_001159503
NP_536700

Location (UCSC) Chr 9: 135.5 – 135.5 Mb Chr 2: 28.47 – 28.47 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Mitochondrial ribosomal protein S2 (MRPS2), otherwise known as uS2m, is a protein that in humans is encoded by the MRPS2 gene. [5]

Contents

Function

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012].

See also

Related Research Articles

MRPS12 protein-coding gene in the species Homo sapiens

28S ribosomal protein S12, mitochondrial is a protein that in humans is encoded by the MRPS12 gene.

MRPS7 protein-coding gene in the species Homo sapiens

28S ribosomal protein S7, mitochondrial is a protein that in humans is encoded by the MRPS7 gene.

MRPS22 protein-coding gene in the species Homo sapiens

28S ribosomal protein S22, mitochondrial is a protein that in humans is encoded by the MRPS22 gene.

MRPL12 protein-coding gene in the species Homo sapiens

39S ribosomal protein L12, mitochondrial is a protein that in humans is encoded by the MRPL12 gene.

MRPL19 protein-coding gene in the species Homo sapiens

39S ribosomal protein L19, mitochondrial is a protein that in humans is encoded by the MRPL19 gene.

MRPS28 protein-coding gene in the species Homo sapiens

28S ribosomal protein S28, mitochondrial is a protein that in humans is encoded by the MRPS28 gene.

MRPS24 protein-coding gene in the species Homo sapiens

28S ribosomal protein S24, mitochondrial is a protein that in humans is encoded by the MRPS24 gene.

MRPS11 protein-coding gene in the species Homo sapiens

28S ribosomal protein S11, mitochondrial is a protein that in humans is encoded by the MRPS11 gene.

MRPS16 protein-coding gene in the species Homo sapiens

28S ribosomal protein S16, mitochondrial is a protein that in humans is encoded by the MRPS16 gene.

MRPS17 protein-coding gene in the species Homo sapiens

28S ribosomal protein S17, mitochondrial is a protein that in humans is encoded by the MRPS17 gene.

MRPS26 protein-coding gene in the species Homo sapiens

28S ribosomal protein S26, mitochondrial is a protein that in humans is encoded by the MRPS26 gene.

MRPL37 protein-coding gene in the species Homo sapiens

39S ribosomal protein L37, mitochondrial is a protein that in humans is encoded by the MRPL37 gene.

MRPS33 protein-coding gene in the species Homo sapiens

28S ribosomal protein S33, mitochondrial is a protein that in humans is encoded by the MRPS33 gene.

MRPS21 protein-coding gene in the species Homo sapiens

28S ribosomal protein S21, mitochondrial is a protein that in humans is encoded by the MRPS21 gene.

MRPL23 protein-coding gene in the species Homo sapiens

39S ribosomal protein L23, mitochondrial is a protein that in humans is encoded by the MRPL23 gene.

MRPS35 protein-coding gene in the species Homo sapiens

28S ribosomal protein S35, mitochondrial is a protein that in humans is encoded by the MRPS35 gene.

MRPS5 protein-coding gene in the species Homo sapiens

28S ribosomal protein S5, mitochondrial is a protein that in humans is encoded by the MRPS5 gene.

MRPL3 protein-coding gene in the species Homo sapiens

Mitochondrial ribosomal protein L3 is a protein that in humans is encoded by the MRPL3 gene.

Mitochondrial ribosomal protein l13 protein-coding gene in the species Homo sapiens

Mitochondrial ribosomal protein L13 is a protein that in humans is encoded by the MRPL13 gene.

MRPS9 protein-coding gene in the species Homo sapiens

Mitochondrial ribosomal protein S9 (MRPS9), otherwise known as uS9m, is a protein that in humans is encoded by the MRPS9 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000122140 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035772 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Mitochondrial ribosomal protein S2" . Retrieved 2018-02-11.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.