Vitamins are organic molecules that are essential to an organism in small quantities for proper metabolic function. Essential nutrients cannot be synthesized in the organism in sufficient quantities for survival, and therefore must be obtained through the diet. For example, vitamin C can be synthesized by some species but not by others; it is not considered a vitamin in the first instance but is in the second. Most vitamins are not single molecules, but groups of related molecules called vitamers. For example, there are eight vitamers of vitamin E: four tocopherols and four tocotrienols.
Casimir Funk was a Polish biochemist generally credited with being among the first to formulate the concept of vitamins after publishing a landmark medical writing in 1912. He highlighted these "vital amines" as critical in fighting significant diseases such as pellagra and rickets, and his analysis influenced a major shift in scientific thinking. His scientific work involved research in Poland, France and the United Kingdom. In 1920, he became a citizen of the United States where he continued his work.
Dame Harriette Chick DBE was a British microbiologist, protein scientist and nutritionist. She is best remembered for demonstrating the roles of sunlight and cod liver oil in preventing rickets.
Sir Edward Mellanby was a British biochemist and nutritionist who discovered vitamin D and its role in preventing rickets in 1919.
Genu valgum, commonly called "knock-knee", is a condition in which the knees angle in and touch each other when the legs are straightened. Individuals with severe valgus deformities are typically unable to touch their feet together while simultaneously straightening the legs. The term originates from Latin genu 'knee' and valgus 'bent outwards', but is also used to describe the distal portion of the knee joint which bends outwards and thus the proximal portion seems to be bent inwards.
Genu varum is a varus deformity marked by (outward) bowing at the knee, which means that the lower leg is angled inward (medially) in relation to the thigh's axis, giving the limb overall the appearance of an archer's bow. Usually medial angulation of both lower limb bones is involved.
Alfred Theodore MacConkey was the British bacteriologist who developed MacConkey's agar, a selective medium that is used in the diagnosis of enteric pathogens. He was born McConkey but appears to have spelled his name "MacConkey" from at least 1881 and in all his published papers
Lucy Wills, LRCP was an English haematologist and physician researcher. She conducted seminal work in India in the late 1920s and early 1930s on macrocytic anaemia of pregnancy. Her observations led to her discovery of a nutritional factor in yeast which both prevents and cures this disorder. Macrocytic anaemia is characterized by enlarged red blood cells and is life-threatening. Poor pregnant women in the tropics with inadequate diets are particularly susceptible. The nutritional factor identified by Lucy Wills was subsequently shown to be folate, the naturally occurring form of folic acid.
Elmer Verner McCollum was an American biochemist known for his work on the influence of diet on health. McCollum is also remembered for starting the first rat colony in the United States to be used for nutrition research. His reputation has suffered from posthumous controversy. Time magazine called him Dr. Vitamin. His rule was, "Eat what you want after you have eaten what you should."
The Lister Institute of Preventive Medicine, informally known as the Lister Institute, was established as a research institute in 1891, with bacteriologist Marc Armand Ruffer as its first director, using a grant of £250,000 from Edward Cecil Guinness of the Guinness family. It had premises in Chelsea in London, Sudbury in Suffolk, and Elstree in Hertfordshire, England. It was the first medical research charity in the United Kingdom. It was renamed the Jenner Institute in 1898 and then, in 1903, as the Lister Institute in honour of the great surgeon and medical pioneer, Dr Joseph Lister. In 1905, the institute became a school of the University of London.
Vitamin D deficiency or hypovitaminosis D is a vitamin D level that is below normal. It most commonly occurs in people when they have inadequate exposure to sunlight, particularly sunlight with adequate ultraviolet B rays (UVB). Vitamin D deficiency can also be caused by inadequate nutritional intake of vitamin D; disorders that limit vitamin D absorption; and disorders that impair the conversion of vitamin D to active metabolites, including certain liver, kidney, and hereditary disorders. Deficiency impairs bone mineralization, leading to bone-softening diseases, such as rickets in children. It can also worsen osteomalacia and osteoporosis in adults, increasing the risk of bone fractures. Muscle weakness is also a common symptom of vitamin D deficiency, further increasing the risk of fall and bone fractures in adults. Vitamin D deficiency is associated with the development of schizophrenia.
Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, along with numerous other biological functions. In humans, the most significant compounds within this group are vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol).
Paul György (April 7, 1893 – March 1, 1976) was a Hungarian-born American biochemist, nutritionist, and pediatrician best known for his discovery of three B vitamins: riboflavin, B6, and biotin. Gyorgy was also well known for his research into the protective factors of human breast milk, particularly for his discoveries of Lactobacillus bifidus growth factor activity in human milk and its anti-staphylococcal properties. He was a recipient of the National Medal of Science in 1975 from President Gerald Ford.
Genevieve Stearns (1892–1997) was a biochemist, most recognized for her accomplishments in research and advocacy for nutrition, especially for women and children.
Helen Marion Macpherson Mackay was a British paediatrician. She made important contributions to the understanding of childhood nutrition and preventive healthcare. Mackay was the first woman fellow of the Royal College of Physicians.
Helen Mary Sang is the head of the Division of Developmental Biology at the Roslin Institute of the University of Edinburgh. Her research considers the development of chickens that cannot spread avian influenza. She has previously served on the Biotechnology and Biological Sciences Research Council.
Douglas Chalmers Watson M.D., F.R.C.P.Ed. was a Scottish physician and writer.
Marie Coates was a British biologist who was an expert in gnotobiosis. She served as President of the Nutrition Society. She used plastic isolators to research the impact of gut microbes on food additives.
Alfred Louis Bacharach, was a British food scientist, scientific author, socialist, and editor of music history and criticism. He wrote as A. L. Bacharach.
Marjorie Giffen MacFarlane (1904–1973) was a British physiologist and biochemist known for her research into anaerobic infection.
