Maria Makrides | |
---|---|
Education | Ph.D., Flinders University |
Scientific career | |
Institutions | University of Adelaide |
Thesis | The role of dietary Omega 3 long chain polyunsaturated fatty acids in tissue composition and visual acuity development of term infants [1] |
Maria Makrides is an Australian professor at the University of Adelaide who works on improving women and babies nutritional health. In 2019 she was made a fellow of the Australian Academy of Science. [2] She is a professor of human nutrition at the Adelaide Medical School, and a theme leader for the South Australian Health and Medical Research Institute (SAHMRI) Women's and Children's Hospital. [3]
Makrides is a Greek-Australian. [4]
Makrides is a dietician, specialising in translational research on the nutrition and health of mothers and babies. [5] She works on health effects of different dietary supplements, including fatty acids and iron during the perinatal period. [2] Makrides work has led to changes in infant formulae as well as improving food laws internationally (Codex Alimentarius). Most recently Maria was part of an international expert advisory group to comment on the composition of follow-up formulas under review by Codex. [6]
Makrides gave a speech on "Standing on the Shoulders of Giants: Great Women Role Models of my Career" when awarded the first woman for a lifetime achievement award. [7] Makrides also has created a network in South Australia to support South Australian women in STEMM. [8] “We’re trying to provide forums and networking opportunities, sponsorship and mentorship for women working in the sciences to reach their full potential”. “Although individual places have their own programs, it’s sometimes helpful to discuss common issues across institutional boundaries. Being a relatively small state, the more we can do together in a collaborative way becomes helpful for women who are trying to make a career in the sciences”. [8]
Makrides is the co-editor of four books, including a textbook in paediatric nutrition, now translated into Chinese, Spanish and Russian. [9] [10] She also leads Trajan Nutrition which has multiple publications on nutritional health. [11] Her publications can be found at Google Scholar. [12] She has over 160 publications including in journals such as JAMA. [13]
Omega−3 fatty acids, also called omega−3 oils, ω−3 fatty acids or n−3 fatty acids, are polyunsaturated fatty acids (PUFAs) characterized by the presence of a double bond three atoms away from the terminal methyl group in their chemical structure. They are widely distributed in nature, being important constituents of animal lipid metabolism, and they play an important role in the human diet and in human physiology. The three types of omega−3 fatty acids involved in human physiology are α-linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). ALA can be found in plants, while DHA and EPA are found in algae and fish. Marine algae and phytoplankton are primary sources of omega−3 fatty acids. DHA and EPA accumulate in fish that eat these algae. Common sources of plant oils containing ALA include walnuts, edible seeds, and flaxseeds as well as hempseed oil, while sources of EPA and DHA include fish and fish oils, and algae oil.
Essential fatty acids, or EFAs, are fatty acids that are required by humans and other animals for normal physiological function that cannot be synthesized in the body. As they are not synthesized in the body, the essential fatty acids – alpha-linolenic acid (ALA) and linoleic acid – must be obtained from food or from a dietary supplement. Essential fatty acids are needed for various cellular metabolic processes and for the maintenance and function of tissues and organs. These fatty acids also are precursors to vitamins, cofactors, and derivatives, including prostaglandins, leukotrienes, thromboxanes, lipoxins, and others.
Fiona Juliet Stanley is an Australian epidemiologist noted for her public health work, her research into child and maternal health as well as birth disorders such as cerebral palsy. Stanley is the patron of the Telethon Kids Institute and a distinguished professorial fellow in the School of Paediatrics and Child Health at the University of Western Australia. From 1990 to December 2011 she was the founding director of Telethon Kids.
Fish oil is oil derived from the tissues of oily fish. Fish oils contain the omega−3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), precursors of certain eicosanoids that are known to reduce inflammation in the body and improve hypertriglyceridemia. There has been a great deal of controversy in the 21st century about the role of fish oil in cardiovascular disease, with recent meta-analyses reaching different conclusions about its potential impact.
Docosahexaenoic acid (DHA) is an omega−3 fatty acid that is an important component of the human brain, cerebral cortex, skin, and retina. It is given the fatty acid notation 22:6(n−3). It can be synthesized from alpha-linolenic acid or obtained directly from maternal milk (breast milk), fatty fish, fish oil, or algae oil. The consumption of DHA (e.g., from fatty fish such as salmon, herring, mackerel and sardines) contributes to numerous physiological benefits, including cognition. As a component of neuronal membranes, the function of DHA is to support neuronal conduction and to allow the optimal functioning of neuronal membrane proteins (such as receptors and enzymes).
Ralph T. Holman was a biochemist whose research focused on lipids and fatty acids, especially the Omega-3 fatty acid. He is regarded as the "Father of Omega-3 fatty acids", coining the term in 1963.
Vegan nutrition refers to the nutritional and human health aspects of vegan diets. A well-planned vegan diet is suitable to meet all recommendations for nutrients in every stage of human life. Vegan diets tend to be higher in dietary fiber, magnesium, folic acid, vitamin C, vitamin E, and phytochemicals; and lower in calories, saturated fat, iron, cholesterol, long-chain omega-3 fatty acids, vitamin D, calcium, zinc, and vitamin B12.
Sandra Eades is a Noongar physician, researcher and professor, and the first Aboriginal medical practitioner to be awarded a Doctorate of Philosophy in 2003. As of March 2020 she is Dean of Medicine at Curtin University.
Jonathan Carapetis is an Australian paediatric physician with particular expertise in infectious disease and Indigenous child health. He is a Winthrop Professor at the University of Western Australia, an infectious diseases consultant at Princess Margaret Hospital for Children, and an Honorary Distinguished Research Fellow of the Walter and Eliza Hall Institute of Medical Research. Carapetis is the Director of the Telethon Kids Institute in Perth, Western Australia.
Only two essential fatty acids are known to be essential for humans: alpha-linolenic acid and linoleic acid. The biological effects of the ω-3 and ω-6 fatty acids are mediated by their mutual interactions. Closely related, these fatty acids act as competing substrates for the same enzymes. The biological effects of the ω-3 and ω-6 fatty acids are largely mediated by essential fatty acid interactions. The proportion of omega-3 to omega-6 fatty acids in a diet may have metabolic consequences. Unlike omega-3 fatty acids and omega-6 fatty acids, omega-9 fatty acids are not classed as essential fatty acids because they can be created by the human body from monounsaturated and saturated fatty acids, and are therefore not essential in the diet.
Georgia Chenevix-Trench is an Australian cancer researcher who investigates genetic predispositions to cancer.
Ingrid Eileen Scheffer is an Australian paediatric neurologist and senior research fellow at the Florey Institute of Neuroscience and Mental Health. Scheffer has made several major advances in the field of epilepsy research. Scheffer is credited with finding the first gene implicated in epilepsy. She has also described and classified novel epileptic syndromes such as Epilepsy limited to Females with Mental Retardation.
Alice Hinda Lichtenstein is an American professor and researcher in nutrition and heart disease. She is an expert on cardiovascular health, and has been recognized for her research on dietary fat. Designated a distinguished university professor, she directs a cardiovascular nutrition laboratory at a USDA center on aging and holds the Stanley N. Gershoff chair in nutrition science and policy at the Friedman School of Nutrition, Tufts University in downtown Boston.
Grace Oladunni Taylor is a biochemist, formerly at University of Ibadan, Nigeria. She was the second woman to be inducted into the Nigerian Academy of Science and the first African awarded a L'Oréal-UNESCO Award for Women in Science.
Clare Elizabeth Collins is an Australian dietician who is Professor of Nutrition and Dietetics at the University of Newcastle. She serves as Director for Research in the School of Health Sciences and Deputy Director of the Priority Research Centre. She was awarded the 2017 Hunter Medical Research Institute Researcher of the Year and is a Fellow of Dietitians Australia.
Elizabeth Jane Elliott is an Australian clinician scientist. She is a Member of the Order of Australia (AM), for services to paediatrics and child health, as well as an Elected Fellow of the Australian Academy of Health and Medical Science (AAHMS), Fellow of the Royal Society of NSW, and Fellow of the Academy of Child and Adolescent Health. She was the first female to win the James Cook Medal, awarded by the Royal Society of NSW for contributions to human welfare. She is a Distinguished Professor of paediatrics at the University of Sydney and a Consultant Paediatrician at the Sydney Children’s Hospitals Network, Westmead, and regarded as a "pioneer in fetal alcohol spectrum disorder, advocacy and patient care".
Laura K. Mackay is an Australian immunologist and Professor of Immunology at the University of Melbourne. Mackay is the Theme Leader in Immunology and Laboratory Head at the Peter Doherty Institute for Infection and Immunity. In 2022, she was the youngest Fellow elected to the Australian Academy of Health and Medical Sciences.
Stephen J. Nicholls is an Australian cardiologist. He was appointed to the position of director of MonashHeart, Monash Health and professor of cardiology, Monash University in October 2018. He is the inaugural clinical director of the Victorian Heart Hospital. He is also the inaugural director of Monash University’s Victorian Heart Institute, an organisation dedicated to creating the cardiovascular health solutions of the future.
Karen Simmer is an Australian paediatrician and professor of Newborn Medicine at the University of Western Australia and is director of two neonatal intensive care units at hospitals in Perth. She also runs the WA Human Milk Bank and is team leader, neonatal gut health, nutrition and development at the Telethon Kids Institute.
Gita Devi Mishra is an Australian epidemiologist who is Professor of Life Course Epidemiology and National Health and Medical Research Council Leadership Fellow at the University of Queensland. She is the director of the Australian Women and Girls’ Health Research Centre. She was awarded the 2022 Royal Australian and New Zealand College of Obstetricians and Gynaecologists Award for Excellence in Women’s Health.